A5077668998- Medical Practices and Rehabilitation
- Plant Pathogens and Fungal Diseases
- Microbial Natural Products and Biosynthesis
- Meningioma and schwannoma management
- Microbial Community Ecology and Physiology
- Marine Sponges and Natural Products
- Marine and coastal ecosystems
- Protist diversity and phylogeny
- Seaweed-derived Bioactive Compounds
- Oceanographic and Atmospheric Processes
- Head and Neck Surgical Oncology
- Fungal Biology and Applications
- Polysaccharides and Plant Cell Walls
- Hearing Loss and Rehabilitation
- Business Process Modeling and Analysis
- Vestibular and auditory disorders
- Hearing Impairment and Communication
- Ear Surgery and Otitis Media
- Spinal Fractures and Fixation Techniques
- Marine and coastal plant biology
- Sinusitis and nasal conditions
- Polar Research and Ecology
- Semantic Web and Ontologies
- Surgical site infection prevention
- Infectious Diseases and Tuberculosis
Heinrich Heine University Düsseldorf
2004-2024
Düsseldorf University Hospital
2019-2024
Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde
2020-2024
Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde
2023
Klinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde
2019-2023
Johannes Gutenberg University Mainz
2004
Peking University
2004
Alfred-Wegener-Institut Helmholtz-Zentrum für Polar- und Meeresforschung
1990-2003
Fraunhofer Institute for Wind Energy Systems
1973-1986
Fractionation of the EtOAc extract a static culture Aspergillus niger isolated from Mediterranean sponge Axinella damicornis yielded eight secondary metabolites, out which seven compounds (2−8) proved to be new natural products, whereas one was identified as known fungal pigment cycloleucomelone (1). The included 3,3'-bicoumarin bicoumanigrin (2), structurally unusual 4-benzyl-1H-pyridin-6-one derivatives aspernigrins A and B (3 4), pyranonigrins A−D (5−8), latter featuring novel...
Abstract Background Skull base osteomyelitis (SBO) is a severe disease not only because of its rapid progression and high mortality: diagnosis treatment are often protracted in more than 30% cases no causative pathogen can be detected. SBO usually preceded by immunodeficiency, which why opportunistic infections caused atypical pathogens must also taken into consideration. In consideration the different possible entities, an interdisciplinary approach with surgical debridement, pathological...
Abstract Purpose For the modeling, execution, and control of complex, non-standardized intraoperative processes, a modeling language is needed that reflects variability interventions. As established Business Process Model Notation (BPMN) reaches its limits in terms flexibility, Case Management (CMMN) was considered as it addresses weakly structured processes. Methods To analyze suitability languages, BPMN CMMN models Robot-Assisted Minimally Invasive Esophagectomy Cochlea Implantation were...
A dematiaceous hyphomycete was isolated from black discoloured areas of the somatic musculature a specimen Atlantic salmon. The fungus caused an endogenous mycosis and obviously must be classified as facultative or opportunistic pathogen marine fish. optimum temperature for strain in range between 20 25 °C, tolerance growth ranged 10 to almost 37 °C. morphological physiological investigation revealed that belongs genus Ochroconis de Hoog et von Arx, which is synonymous with Scolecobasidium...
Postoperative wound infections after cochlear implantation are rare but sometimes serious and can lead to explantation. Therefore, perioperative antibiotic administration is often recommended. However, in clinical practice, the type duration of prophylaxis varies between different centers. The aim this study was investigate role preventing postoperative complications.
Abstract The documentation of surgeries is usually created from memory only after the operation, which an additional effort for surgeon and afflicted with possibility imprecisely, shortend reports.The display process steps in form checklists automatic creation surgical completed could serve as a reminder, standardize procedure save time surgeon. Based on two works Reutlingen University, implemented dynamic Business Process Modelling Notation (BPMN) models storage times at step was completed,...
Multiple synostoses syndrome (OMIM: #186500, #610017, #612961, #617898) is a genetically heterogeneous group of autosomal dominant diseases characterized by abnormal bone unions. The joint fusions frequently involve the hands, feet, elbows or vertebrae. Pathogenic variants in FGF9 have been associated with multiple type 3 (SYNS3). So far, only five different missense that cause SYNS3 reported 18 affected individuals. Unlike other syndromes, conductive hearing loss has not SYNS3. In this...
Introduction Cochlear implants (CI) are an established and proven method of auditory rehabilitation. In addition, neuromodulation systems such as peripheral nerve field stimulation (PNFS) for treating neuropathic pain gaining increasing importance. To date, there is limited information regarding the concurrent use these implanted potential electromagnetic interferences. this context, case report addresses simultaneous cochlear stimulation.
Introduction Due to rapid progression and high mortality rates - especially in immunodeficient patients osteomyelitis (OM) of the skull base is a severe disease. The different origins show similar radiological findings, therefore interdisciplinary approaches including surgical debridement, pathological sampling, structured microbiological diagnostics counselling by antibiotic stewardship teams are key successful therapy.
Einleitung Die Schädelbasisosteomyelitis (SBO) ist aufgrund des potentiell rasanten Progresses und der hohen Mortalität – insbesondere bei Immundefizienz ein schwerwiegendes Krankheitsbild. Verschiedene Ätiologien lassen sich radiologisch häufig nicht differenzieren, weshalb zur erfolgreichen Behandlung interdisziplinärer Ansatz mit chirurgischem Debridement, pathologischer Sicherung, strukturierter mikrobiologischer Diagnostik antibiotischer Therapie im Rahmen eines Antibiotic-Stewartships...
Bei vestibulären Schwannomen (VS) wird der einseitige Hörverlust häufig als gravierendes Symptom empfunden. Beim retrosigmoidalen Zugang auch unter Strahlentherapie kann Erhalt des Hörvermögens nicht garantiert werden, beim translabyrinthären ist Verlust unvermeidlich. Im klinischen Kontext es jedoch schwierig, eine ausreichend prädiktive Aussage in Bezug auf einen zu erwartenden Erfolg mittels einer Cochlea Implantation (CI) tätigen. Retrospektiv wurden 29 Patienten ausgewertet, die nach...
Introduction After every surgical procedure, the surgeon is responsible for preparing an individual report. This often done with a time delay and relies on correct memory of surgeon, which can lead to inaccurat documentation. Semiautomatic recording, systematic storage text processing all intraoperative data would be saving form foundation quality management subsequent analysis.
Einleitung Cochlea-Implantate (CI) sind ein etabliertes und bewährtes Verfahren der Hörrehabilitation. Daneben gewinnen Neuromodulationssysteme, wie die periphere Nervenfeldstimulation (PNFS) zur Behandlung neuropathischer Schmerzen, zunehmend an Bedeutung. Bislang gibt es nur begrenzte Informationen bezüglich gleichzeitigen Anwendung dieser implantierten Systeme möglicher elektromagnetischer Interferenzen.
Einleitung Nach jedem chirurgischen Eingriff ist die Erstellung eines individuellen OP-Berichtes Aufgabe des Operateurs. Dies geschieht häufig mit zeitlicher Verzögerung und aus der Erinnerung heraus, was zu einer fehlerhaften Dokumentation führen kann. Die semiautomatische Erfassung, systematische Speicherung Textverarbeitung aller intraoperativen Daten würde nicht nur eine Zeitersparnis für den Operateur ermöglichen, sondern auch Grundlage Qualitätssicherung zukünftige Datenanalysen schaffen.