A5078544395- Monoclonal and Polyclonal Antibodies Research
- vaccines and immunoinformatics approaches
- Land Use and Ecosystem Services
- Glycosylation and Glycoproteins Research
- Microfluidic and Bio-sensing Technologies
- Advanced Biosensing Techniques and Applications
- Protein purification and stability
- Analytical Chemistry and Chromatography
- Biochemical effects in animals
- Neurogenetic and Muscular Disorders Research
- Pharmacological Effects and Assays
- Regional Development and Environment
- Advanced Chemical Sensor Technologies
- Biochemical Analysis and Sensing Techniques
- Nephrotoxicity and Medicinal Plants
- Conservation, Biodiversity, and Resource Management
- Amyotrophic Lateral Sclerosis Research
- Sustainable Industrial Ecology
- Plant Ecology and Taxonomy Studies
- Phytochemistry and Biological Activities
- Chemical Reactions and Isotopes
- Plant-based Medicinal Research
- Genetic Neurodegenerative Diseases
- Biopolymer Synthesis and Applications
- Regional resilience and development
Shaanxi University of Technology
2023-2025
Chongqing Bureau of Geology and Minerals Exploration
2024
Palo Alto University
2023
Stanford University
2023
Shaanxi Research Association for Women and Family
2023
Chongqing Technology and Business University
2022
The relationship between land use changes and regional carbon storage is closely linked. Identifying evolving trends concerning influencing factors on under future scenarios key in order to achieve the “dual carbon” goals. Using Chongqing as a case study, this study integrated advantages of PLUS model, InVEST geographic detector model. It conducted simulations type data natural development (ND) ecological protection (EP), identified regarding storage. results were follows: (1) model...
The management of regional eco-environmental risks is the key to promoting economic sustainability from macro level, and accurate evaluation evolutionary trends ecological risk in future high importance. In order clearly identify possible impact development scenario selection for Chengdu-Chongqing Economic Zone (C-C E Zone) on evolution landscape (LER), we introduced Patch-generating Land Use Simulation (PLUS) model simulate land use data C-C 2030 2050 two scenarios: natural (ND) protection...
As a famous tonic herb, Cistanches Herba is known for its broad medicinal functions, especially hormone balancing, anti-aging, anti-dementia, anti-tumor, anti-oxidative, neuroprotective, and hepatoprotective effects. This study aims to provide comprehensive bibliometric analysis of studies on Cistanche identify research hotspots frontier topics the genus. Based metrological software CiteSpace, 443 related papers were quantitatively reviewed. The results indicate that 330 institutions from 46...
Melatonin (MT), as a hormone regulating the rhythm of sleep, is widely used in health products. However, illicit and excessive use MT might cause undesirable effects. Therefore, it essential to establish highly sensitive specific rapid methods for analysis In this study, we established indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) chemiluminescent enzyme immunoassay (ic-CLEIA) selective detection Under optimal conditions, half-maximum inhibitory concentration (IC50 value)...
The 2023 Nobel Prize in Chemistry honors the groundbreaking contributions of Alexei Ekimov, Louis Brus, and Moungi Bawendi to field quantum dots (QDs). In this spirit, we developed a direct competitive QD fluorescence immunoassay (dc-QD-FLISA) detect aristolochic acid type I (AAI), potent carcinogen found herbal remedies. Unexpectedly, dc-QD-FLISA exhibited lower sensitivity than that an indirect enzyme-linked immunosorbent assay (ic-ELISA), contrary our initial expectations. This...
Background 3-caffeoylquinic acid (3-CQA), a member of the chlorogenic family, possesses diverse pharmacological properties, such as scavenging, antioxidant, and antiapoptotic activity, rendering substantial value to alimentary consumables therapeutic substances. However, pervasiveness non-standard practices, notably misuse abuse indigenous botanicals, coupled with inherent susceptibility 3-CQA degradation under light heat exposure, engenders discernible disparateness in quality profiles same...
Virus-like particles (VLPs) are nanostructures with the potential to present heterologous peptides at high density, thereby triggering heightened immunogenicity. RNA bacteriophage MS2 VLPs a compelling delivery platform among them. However, notable hurdle arises from immune response toward coat protein, swiftly eliminating subsequent vaccinations via same vector. Although larger inserts effectively mask carrier epitopes, current research predominantly focuses on displaying short conserved...
TAR DNA binding protein-43 (TDP-43) aggregation is a hallmark for many neurodegenerative diseases including amyotrophic lateral sclerosis, frontotemporal dementia and Huntington’s disease. These protein aggregates can disrupt neuronal function contribute to neurodegeneration. Previous studies have uncovered that adenosine triphosphate (ATP) promising molecule dock onto the TDP-43 RNA recognition motif (RRM) region reduce amyloid-like aggregation. This provides potential therapeutic strategy...
N-acetylneuraminic acid is an active ingredient in tonic foods and important additive biopharmaceuticals. To address the limitations of existing methods quantification, we developed immunoassay based on antibodies induced hens using artificial antigen, showing high sensitivity specificity with no cross-reactivity eight analogues. An IgY-based indirect competitive enzyme-linked immunosorbent assay showed a detection range 1.14 to 70.08 ng/mL limit 0.57 ng/mL. In spiked samples, recoveries by...
Green development is key to promoting regional sustainable development. We construct an evaluation index system for green levels based on the “sansheng” dimensions—production, living, and ecology. rely (production, ecology) dimensions, combined with analytic hierarchy process (AHP) entropy weight method analyze indicator weights, levels. This enables identification of evolution patterns analysis driving factors in Chengdu-Chongqing economic zone from perspective. The results indicate that:...
Antibody mimetics is a novel antibody engineering approach after the development of polyclonal, monoclonal antibodies, and genetically engineered fragments. Inspired by structure function natural offer many advantages over conventional antibodies can be constructed protein-directed evolution, peptide design synthesis, or fusion complementarity-determining regions through intervening framework regions. A series parent protein/peptide structures technical roadmaps have been established to...
Antibody mimetics is a novel antibody engineering approach after the development of polyclonal, monoclonal antibodies, and genetically engineered fragments. Inspired by structure function natural offer many advantages over conventional antibodies can be constructed protein-directed evolution, peptide design synthesis, or fusion complementarity-determining regions through intervening framework regions. A series parent protein/peptide structures technical roadmaps have been established to...