- Cancer Treatment and Pharmacology
- Colorectal Cancer Treatments and Studies
- Breast Cancer Treatment Studies
- 2D Materials and Applications
- Lung Cancer Treatments and Mutations
- Intracranial Aneurysms: Treatment and Complications
- Electronic and Structural Properties of Oxides
- Glioma Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Gastric Cancer Management and Outcomes
- Neurosurgical Procedures and Complications
- Lymphoma Diagnosis and Treatment
- Organic and Molecular Conductors Research
- Topological Materials and Phenomena
- Graphene research and applications
- Breast Lesions and Carcinomas
- Vascular Malformations Diagnosis and Treatment
- Lung Cancer Research Studies
- HER2/EGFR in Cancer Research
- Chemotherapy-induced cardiotoxicity and mitigation
- Chalcogenide Semiconductor Thin Films
- Estrogen and related hormone effects
- Cerebrospinal fluid and hydrocephalus
- Chronic Lymphocytic Leukemia Research
- Cancer therapeutics and mechanisms
University of Trento
2022-2025
Italian Institute of Technology
2021-2024
University of L'Aquila
2019-2023
Università Cattolica del Sacro Cuore
2023
Institut des NanoSciences de Paris
2022
Centre National de la Recherche Scientifique
2022
Sorbonne Université
2022
Agostino Gemelli University Polyclinic
2021
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
1996-2012
Medica (Italy)
2004-2010
Abstract BACKGROUND The aim of the current randomized Phase II study was to investigate efficacy and safety capecitabine combined with irinotecan as first‐line treatment in metastatic colorectal carcinoma (CRC). METHODS A total 140 patients received at a dose 1250 mg/m 2 twice daily on Days 2–15 either 300 Day 1 (Arm A) or 150 8 B) every 3 weeks. During course study, enrollment continued using lower doses (1000 daily) A: 240 ; Arm B: 120 ) improve profile combinations. RESULTS Efficacy...
Screening, a ubiquitous phenomenon associated with the shielding of electric fields by surrounding charges, has been widely adopted as means to modify material’s properties. While most studies have relied on static changes screening through doping or gating thus far, here we demonstrate that can also drive onset distinct quantum states ultrafast timescale. By using time- and angle-resolved photoemission spectroscopy, show intense optical excitation 1T-TiSe 2 , prototypical charge density...
A flat energy dispersion of electrons at the Fermi level a material leads to instabilities in electronic system and can drive phase transitions. Here we introduce method induce band two-dimensional (2D) materials. We show that be achieved by sandwiching 2D two cesium (Cs) layers. apply this monolayer graphene investigate combination angle-resolved photoemission spectroscopy experiment calculation. Our work highlights charge transfer, zone folding bands covalent bonding between C Cs atoms are...
Misfit layer compounds are heterostructures composed of rocksalt units stacked with few-layer transition metal dichalcogenides. They host Ising superconductivity, charge density waves, and good thermoelectricity. The design misfits' emergent properties is, however, hindered by the lack a global understanding electronic transfer among constituents. Here, performing first-principles calculations, we unveil mechanism controlling demonstrate that always donor dichalcogenides acceptors. We show...
Introdução: Com a implementação da Rede Cegonha em 2011, o objetivo do Ministério Saúde era melhorar assistência à gestação, parto e pós-parto, reduzir mortalidade materna infantil. O monitoramento programa é importante para que as mudanças sejam realizadas fim de qualificar cada vez mais ao parto. Objetivo: Avaliar boas práticas atenção após um hospital público cidade Bauru, São Paulo. Métodos: Trata-se estudo transversal, retrospectivo, documental, desenvolvido com análise prontuários...
✓ A case of benign intracranial hypertension with polyradiculopathy and spinal pain is reported. Radioactive iodinated serum albumin (RISA) cisternography demonstrated the absence cerebrospinal fluid (CSF) flow into cisterns, gave evidence CSF absorption through arachnoid villi.
The compound CuTe (vulcanite) undergoes a quasi one dimensional charge density wave (CDW) at $T< T_{\mathrm{CDW}}=335$ K with $5\times1\times2$ periodicity. mechanism its origin is debated. Several theoretical works claimed that semilocal functionals are unable to describe occurrence and ascribed formation only strong electron-electron interaction. Moreover, the possible role of quantum anharmonicity has not been addressed. Here, by performing anharmonic calculations, we show correctly CDW...
The photoluminescence spectrum of a single-layer boron nitride remains elusive, marked by enigmatic satellites that hint at significant but unidentified exciton-phonon coupling.Here, employing first principles approach based on the many-body cumulant expansion charge response, we calculate optical absorption and single layer nitride. We identify specific scattering channels unravel their impact spectra thereby providing an interpretation experimental features. Finally, show that, even in...
Photoexcited GeTe undergoes a nonthermal phase transition from rhombohedral to rocksalt crystalline phase. The microscopic mechanism and the nature of are unclear. By using constrained density functional perturbation theory by accounting for quantum anharmonicity within stochastic self-consistent harmonic approximation, we show that is strongly first order does not involve phonon softening, at odds with thermal one. driven closure single particle gap in photoexcited Finally, ultrafast x-ray...
A Phase II confirmatory multicenter trial was performed to evaluate a combination of epirubicin, cisplatin, and continuous infusion 5-fluorouracil (ECF) in treating patients with advanced gastric cancer.Fifty-three locally (n = 7) or metastatic 46) cancer received dose epirubicin (50 mg/m2) cisplatin (60 intravenously every 21 days for eight cycles (200 mg/m2/day) by intravenous consecutive weeks, administered through central line using an external pump.Eight complete responses 22 partial...
The authors report their personal experience with the administration of microdoses morphine hydrochloride by intraventricular route through a subcutaneous reservoir for treatment paraneoplastic painful syndrome cervicofacial region in 38 patients. results obtained are very encouraging.
The FAST is a 2 × factorial trial addressing two questions: (1) the role of replacing cisplatin (P) with non-platinum agent, vinorelbine (N), and (2) adding third ifosfamide (I), in doublet based on gemcitabine (G). A total 433 stage IIIB–IV non-small cell lung cancer (NSCLC) patients were randomised to one four arms: gemcitabine–cisplatin (GP), gemcitabine–vinorelbine, gemcitabine–ifosfamide-cisplatin or gemcitabine–ifosfamide–vinorelbine. Two comparisons performed: N- vs P-containing...
We report an update of our results a trial high-dose folinic acid (HDFA) and 5-fluorouracil (5-FU) in advanced breast cancer. Thirty-eight patients with mainly refractory cancer were treated the following regimen: HDFA (200 mg/m2/day) 5-FU (340, 370, 400 given immediately afterwards, for 5 consecutive days every 4 weeks. Of 36 evaluable patients, 3 achieved complete remission (8%) 13 partial (36%) overall response rate 44%, while 11 (30%) had stable disease. Thirteen out sixteen responders...