A5078201248- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- biodegradable polymer synthesis and properties
- Polymer Surface Interaction Studies
- Hydrogels: synthesis, properties, applications
- Clay minerals and soil interactions
- Graphene and Nanomaterials Applications
- Therapeutic Uses of Natural Elements
- Nanocomposite Films for Food Packaging
- 3D Printing in Biomedical Research
- Periodontal Regeneration and Treatments
- Silk-based biomaterials and applications
- Nanoparticle-Based Drug Delivery
- Wound Healing and Treatments
- Iron oxide chemistry and applications
- Orthopaedic implants and arthroplasty
- Dental Implant Techniques and Outcomes
- Cellular Mechanics and Interactions
- Tissue Engineering and Regenerative Medicine
- Advanced Drug Delivery Systems
- Collagen: Extraction and Characterization
- Advanced Polymer Synthesis and Characterization
- Neonatal Health and Biochemistry
- Dental materials and restorations
- Calcium Carbonate Crystallization and Inhibition
Jinan University
2016-2025
V.I.Shumakov Federal Research Center of Transplantology and Artificial Organs
2011-2025
Zhuhai Institute of Advanced Technology
2022-2025
Materials Science & Engineering
2006-2025
Ministry of Education of the People's Republic of China
2015-2024
Hohai University
2018-2023
Shandong Agricultural University
2018
University of Jinan
2017
Guangzhou Experimental Station
2014
First Affiliated Hospital of Jinan University
2008
This work developed novel chitosan-halloysite nanotubes (HNTs) nanocomposite (NC) scaffolds by combining solution-mixing and freeze-drying techniques, aimed to show the potential application of in tissue-engineering. The hydrogen bonding electrostatic attraction between chitosan HNTs were confirmed spectroscopy morphology analysis. interfacial interactions resulted a layer absorbed on surfaces HNTs. determination mechanical thermal properties demonstrated that NC exhibited significant...
Halloysite nanotubes (HNTs) have a unique tubular structure in nanoscale, and shown potential as novel carriers for various drugs. Coating the with hydrophilic polymer shell can significantly decrease toxicity provide colloidal stability during blood circulation. Here, we synthesized chitosan grafted HNTs (HNTs-g-CS) investigated their nano-formulation anticancer drug curcumin. The properties of HNTs-g-CS were characterized using water contact angle, zeta-potential, Fourier transform...
Halloysite nanotubes (HNTs) are natural aluminosilicates with unique hollow lumen structure, also having high specific area, good biocompatibility, nontoxicity, and low price. Here, we designed a chitosan oligosaccharide-grafted HNTs (HNTs-g-COS) as doxorubicin (DOX) carrier for treating breast cancer both in vitro vivo. The structure of HNTs-g-COS was first characterized by various methods. showed positively charged surface improved hemocompatibility. DOX-loaded (DOX@HNTs-g-COS) released...
The addition of halloysite nanotubes into chitosan sponges can simultaneously improve the mechanical, hemostatic and wound healing property chitosan.
3D bioprinting, a promising technology by precisely positioning cell-laden biomaterials to fabricate complex functional artificial tissues and organs, has potential applications in regenerative medicine drug discovery. However, the printing of large-scale constructs with high structural fidelity is still major challenge. One main bottlenecks development bioink materials. Herein, double network hydrogel that combines superior shear-thinning recovery properties gellan gum (GG) rapid UV...
To improve water solubility and bioavailability, curcumin (Cur) was encapsulated by liposomes (Cur-Lip), which further coated with thiolated chitosan (CSSH) to form liposomal hydrogels (CSSH/Cur-Lip gel). The were thermosensitive in situ injectable performance, fluidic at room temperature gelled quickly 37 °C. cumulative release ratio of the 200 μM CSSH/Cur-Lip gel 31.57 ± 1.34% 12 h, could effectively delay curcumin. Worthily, resilient compressive even after five cycles compression....
To carry doxorubicin (DOX) on breast cancer site effectively, halloysite nanotubes conjugated with poly(ethylene glycol) and folate (HNTs-PEG-FA) is designed as a targeted drug delivery system. Halloysite (HNTs) are shortened to ∼200 nm by ultrasonic scission functionalized amide groups conjugate N-hydroxylsuccinimide-polyethylene glycol carboxylic acid (NHS-PEG-COOH) (FA). DOX@HNTs-PEG-FA prepared loading DOX HNTs-PEG-FA via physical adsorption. The sustained controlled release of from up...
Chitin nanocrystals (CNCs), rod-like crystalline nanoparticles from natural sources, show high aspect ratio, modulus, and excellent reinforcing ability toward polymers. In this study, CNCs aqueous dispersions were first prepared by acid hydrolysis of raw chitin. The resulting dispersion was investigated polarized optical microscopy rheometry at different concentrations. A nematic liquid crystals phenomenon with increasing solid concentration is found in the dispersion. When beyond 5 wt %,...