A5006507963- Electrospun Nanofibers in Biomedical Applications
- Polymer Surface Interaction Studies
- Nanoparticle-Based Drug Delivery
- Advanced Sensor and Energy Harvesting Materials
- RNA Interference and Gene Delivery
- Hydrogels: synthesis, properties, applications
- Enzyme-mediated dye degradation
- Lignin and Wood Chemistry
- Nanoplatforms for cancer theranostics
- Biochemical and biochemical processes
- Analytical chemistry methods development
- Advanced Thermoelectric Materials and Devices
- Heusler alloys: electronic and magnetic properties
- 2D Materials and Applications
- Advanced Drug Delivery Systems
- Topological Materials and Phenomena
- Ocular Surface and Contact Lens
- Medical and Biological Ozone Research
- Supramolecular Chemistry and Complexes
- Iron-based superconductors research
- Forensic Toxicology and Drug Analysis
- Corneal Surgery and Treatments
- Phase-change materials and chalcogenides
- Shape Memory Alloy Transformations
- Thermal properties of materials
Jinan University
2013-2023
Key Laboratory of Guangdong Province
2018
China Guangzhou Analysis and Testing Center
2011
Lignin nanoparticles (LNPs), as a special aggregate of renewable and biodegradable lignin available in abundant amounts, are perfect building-block material because their advantages, including good dispersibility water, great biocompatibility, eco-friendly characteristics. To exploit promising method producing LNPs, we developed simple sustainable synthesis approach using recycled γ-valerolactone (GVL)/water binary solvent (GWBS). Up to 200 g/L from several sources could be completely...
Understanding the molecular mechanism of lignin nanoparticle (LNP) formation will precisely instruct its functionalization, which is importance for biomass valorization.
Herein we have combined the molecular imprinting technique and thermally-initiated precipitation polymerization to develop novel molecularly imprinted poly(methacrylic acid) nanospheres (PMAA MIPNs) for sustained release of gatifloxacin (GFLX). In process, ethylene glycol dimethacrylate (EGDMA) GFLX were used as cross-linker template, respectively. The effects reaction medium concentration monomers such MAA, EGDMA systematically investigated. Uniform with diameter equal 136.0 ± 8.1 nm...
Exosomes are deliverers of critically functional proteins, capable transforming target cells in numerous cancers, including hepatocellular carcinoma (HCC). We hypothesize that the motility HCC can be featured by comparative proteome exosomes. Hence, we performed super-SILAC-based MS analysis on exosomes secreted three human cell lines, non-motile Hep3B cell, and motile 97H LM3 cells. More than 1400 exosomal proteins were confidently quantified each with highly biological reproducibility....
Supramolecular hydrogels derived from natural nucleoside have promising applications for on-demand drug release with controlled on/off switch and adjustable kinetics in response to various stimuli.
In this study, we present a simple yet efficient method to modify polyester electrospun fibrous scaffolds by polysaccharide–protein multilayer formation based on electrostatic interactions. Chitosan (CS) and gelatin (Gel) was selected as the polycation polyanion, respectively, build polyelectrolyte multilayers (PEMs) poly-L-lactide (PLLA) fibers via layer-by-layer (LbL) self-assembly technique. A positively charged surface first created aminolysis reaction of esters in PLLA backbone...
A soft and biocompatible hydrogel exhibiting a higher loading the sustained release of gatifloxacin (GFLX) was developed as potential matrix to fabricate therapeutic contact lens for curing bacterial keratitis. 2-hydroxyethyl methacrylate (HEMA) five other kinds vinyl monomers with different side groups were used co-monomers. Copolymerization took place in cornea shaped mould via gradient temperature-elevating method. The results drug vitro experiments showed that P(HEMA-co-MAA) achieved...
In order to effectively immobilize and control release of basic fibroblast growth factor (bFGF) from alginate microspheres, heparin-conjugated (H-Alg) was first synthesized by covalent binding. Then multilayered H-Alg microspheres (multilayered microspheres) were fabricated via an electrostatic droplet generation technique followed a layer-by-layer (LbL) self-assembly technique. Several techniques such as Fourier transform infrared spectroscopy (FTIR), 1H-NMR, zeta potential analysis...
Janus hybrid nanoparticles synthesized through seeded dispersion polymerization show excellent drug loading capacity and chemo-photothermal effects for anti-tumour treatment.
In this study, calcium-alginate microgels coated with a polyelectrolyte multilayer (PEM) were fabricated as controlled-release system. This system was constructed via an electrostatic droplet generation technique followed by layer-by-layer (LbL) self-assembly technique. The reported easy method of preparing microgels, due to their mild preparation conditions and ability preserve the biological activity encapsulated drugs. With LbL technique, PEM could be on attributed attraction between...
ABSTRACT In this study, poly( l ‐lactic acid) (PLLA) was prepared by four typical approach systems, namely, solid–liquid phase‐separation processes from PLLA–dioxane at −80°C, PLLA–dioxane–water PLLA–tetrahydrofuran (THF) and PLLA–THF 18°C. The microstructural characteristics crystallization behaviors of PLLA were investigated scanning electron microscopy, differential calorimetry, X‐ray diffraction, Fourier transform infrared spectroscopy. the binary system ternary system, solvent froze...
In this paper, we report an efficient preparation of silver telluride by rapid solid-state microwave heating. Single phase products have been obtained within as little 30 min irradiation time. The rate the synthesis is significantly increased compared to solid state reaction method in a conventional furnace. quality as-prepared samples are attested structural, compositional and magnetoresistance characterizations.