Wael El-Sheshtawy

ORCID: 0000-0003-2630-2624
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About
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Research Areas
  • Advanced Radiotherapy Techniques
  • Advances in Oncology and Radiotherapy
  • Cancer Diagnosis and Treatment
  • Bladder and Urothelial Cancer Treatments
  • Breast Cancer Treatment Studies
  • Colorectal Cancer Screening and Detection
  • Urinary and Genital Oncology Studies
  • Breast Lesions and Carcinomas
  • Liver Disease Diagnosis and Treatment
  • Vascular Tumors and Angiosarcomas
  • Prostate Cancer Diagnosis and Treatment
  • Drug Transport and Resistance Mechanisms
  • Colorectal Cancer Surgical Treatments
  • Head and Neck Cancer Studies
  • Fungal Infections and Studies
  • Radiation Therapy and Dosimetry
  • Lung Cancer Research Studies
  • Management of metastatic bone disease
  • Acute Lymphoblastic Leukemia research
  • Sarcoma Diagnosis and Treatment
  • Glioma Diagnosis and Treatment
  • Cancer Treatment and Pharmacology
  • Cutaneous lymphoproliferative disorders research
  • Radiomics and Machine Learning in Medical Imaging
  • Lung Cancer Treatments and Mutations

Al-Azhar University
2017-2025

Al-Azhar University
2020

Background: Intensity-modulated radiotherapy (IMRT) is the standard treatment for locally advanced head and neck cancer (LAHNC). However, potential role of adaptive in preserving salivary function enhancing quality life (QoL) remains underexplored. Aim: This study aimed to assess QoL following offline IMRT patients with LAHNC undergoing concurrent chemotherapy. Methods: Salivary were evaluated during last follow-up treated a single IMRT. Unstimulated flow rate (uSFR) was measured function,...

10.21608/resoncol.2025.356590.1216 article EN cc-by Research in Oncology 2025-03-19

Background: Studying single-nucleotide polymorphisms (SNPs) in xenobiotic-transporting and metabolizing enzyme genes before administering the doxorubicin hydrochloride cyclophosphamide (AC) regimen may help optimize breast cancer (BC) treatment for individual patients. Objective: Genotyping specific SNPs on encoding transport metabolism of AC study their association with its chemotherapeutic toxicity. Method: This prospective cohort was conducted two hospitals Egypt. Before receiving...

10.3390/ph18040539 article EN cc-by Pharmaceuticals 2025-04-07

Primary pulmonary extraskeletal Ewing sarcoma (EES)/ primitive neuroectodermal tumor is an extremely rare with only few cases reported in the literature. In this study, we present two of primary EES diagnosed and treated at our institution. The median age was 20 years (range: 19–21). Cough, dyspnea, hemoptysis were predominant features presentation, associated a large lung mass on imaging. Image-guided core needle biopsies diagnostic modalities for both patients. Initial histopathology...

10.4103/ejb.ejb_48_16 article EN cc-by Egyptian Journal of Bronchology 2017-04-25

To evaluate dose differences predicted between using Anisotropic Analytical Algorithm (AAA) and Acuros XB (AXB) in patients diagnosed with locally advanced non-small cell lung cancer (NSCLC) treated intensity modulated radiation therapy (IMRT).A phantom study was done to the prediction accuracy of AXB AAA beyond low-density medium by comparing calculated measurement results. Thirty-two NSCLC were subjected IMRT. The regimen 60 Gy over 30 fractions. Effects on planning target volume (PTV)...

10.3233/xst-210942 article EN Journal of X-Ray Science and Technology 2021-09-17

Background: The control of schistosomiasis in Egypt was associated with changes the prevalence and histopathology urinary bladder cancer.Aim: To investigate histological pattern among patients treated for cancer at our institution over a 5-year period.Methods: This retrospective study conducted by reviewing medical records 632 departments Urology Clinical Oncology, Al Azhar Faculty Medicine, between January 2011 December 2015.Results: included patients. Their age ranged from 27-87 years old...

10.21608/resoncol.2017.869.1023 article EN cc-by Research in Oncology 2017-06-01

Background: High-grade gliomas (HGG) represent the commonest primary adult brain tumors.Radiotherapy plays an important role in management of this disease. Aim study:To assess patterns failure, treatment-related toxicities, progression-free survival (PFS), and overall (OS), following limited-margins.Patients Methods: In prospective phase II study, patients with HGG have been treated IMRT using ESTRO-ACROP contouring guidelines that not include peritumoral edema gross target volume (GTV)...

10.21608/aimj.2020.43502.1325 article EN cc-by-sa Al-Azhar International Medical Journal /Al-Azhar International Medical Journal 2020-12-20

Background: from clinical and pathologic aspects, locally advanced breast cancer (LABC) can be considered a relatively heterogeneous group of tumors.Objective: we aimed to evaluate local control after breast-conserving surgery in patients with who received neoadjuvant chemotherapy for down staging.Patients Methods: retrospective study was performed include underwent (anthracylcine based regimen followed by taxans).The clinical, pathologic, surgical factors that could contribute locoregional...

10.21608/ejhm.2019.26599 article EN The Egyptian Journal of Hospital Medicine 2019-01-01

Background: bladder cancer (BC) is a life menacing disease that harvested considerable number of deaths anniversary. Noteworthy, BC the most predominant among Egyptian men with prevalence rate more than 15% resulting in 8,000 yearly. Aim work: this study was implemented to retrieve which modality (Radical cystectomy (RC) vs bladder-sparing therapy (BST)) had superiority management patients muscle-invasive (MIBC). Methods: we performed retrospective, case-control from archived files at...

10.12816/ejhm.2019.26605 article EN The Egyptian Journal of Hospital Medicine 2019-01-01

Background: from clinical and pathologic aspects, locally advanced breast cancer (LABC) can be considered a relatively heterogeneous group of tumors. Objective: we aimed to evaluate local control after breast-conserving surgery in patients with who received neoadjuvant chemotherapy for down staging. Patients Methods: retrospective study was performed include underwent (anthracylcine based regimen followed by taxans). The clinical, pathologic, surgical factors that could contribute...

10.12816/ejhm.2019.26599 article EN The Egyptian Journal of Hospital Medicine 2019-01-01

Background: bladder cancer (BC) is a life menacing disease that harvested considerable number of deaths anniversary.Noteworthy, BC the most predominant among Egyptian men with prevalence rate more than 15% resulting in 8,000 yearly.Aim work: this study was implemented to retrieve which modality (Radical cystectomy (RC) vs bladder-sparing therapy (BST)) had superiority management patients muscle-invasive (MIBC).Methods: we performed retrospective, case-control from archived files at Urology...

10.21608/ejhm.2019.26605 article EN The Egyptian Journal of Hospital Medicine 2019-01-01

Background: worldwide, prostate cancer is the second most common and fifth leading cause of death from in men.Objective: to study impact hormonal treatment patients with metastatic prostatic carcinoma.………………………………………….Subject Methods: This retrospective included all diagnosed cancer, treated at our center between year 2007 2016, data was reviewed charts analyzed for outcome.………………………………………... Results: 39 patients, 21 (52.6 %) had subjected primary bilateral orchiectomy as first line...

10.21608/aimj.2020.22125.1060 article EN cc-by-sa Al-Azhar International Medical Journal /Al-Azhar International Medical Journal 2020-01-26

Background: breast cancer is the most prevalent diagnosed in females worldwide.Radiotherapy improves survival patients.Consistent evidence emerges as regard benefit of inclusion IMN (internal mammary lymph nodes).Novel radiation techniques decreased incidence toxicity from radiotherapy.Aim work: Assessment acute and moderately late toxicity, assessing doses to normal structures, overall progression-free survival.Patients Methods: this study included 41 patient received postoperative...

10.21608/aimj.2020.27527.1194 article EN cc-by-sa Al-Azhar International Medical Journal /Al-Azhar International Medical Journal 2020-06-10

Background: major progress in the management of non-small cell lung cancer emerged last years.Survival rate markedly improved locally advanced with use concurrent chemo-radiotherapy treatment.Novel radiation techniques decreased incidence toxicity from radiotherapy.Aim work: Assess toxicity, local control, progression-free and overall survival resulting usage treatment using intensitymodulated radiotherapy technique.Patient methods: this study included patients stage III nonsmall cancer,...

10.21608/aimj.2020.30559.1230 article EN cc-by-sa Al-Azhar International Medical Journal /Al-Azhar International Medical Journal 2020-07-13

Background:The most important event of RT (Radiation Therapy)is to dependably expand the positions target volume while limiting side effects normal tissues.Thusly, day by treatment arrangement is considered as a basic necessity in Therapy) for an exact and setup accuracy treatmentbut still Set-up errors are inevitable features radiation therapy process.Aim work:To evaluate three dimensional set-up propose optimum margins coverage inthe pelvic therapy.Patient Methods: This study aiming...

10.21608/aimj.2020.28802.1209 article EN cc-by-sa Al-Azhar International Medical Journal /Al-Azhar International Medical Journal 2020-08-26

Background: Laparoscopic surgery for rectal cancer is widely performed all over the world and several randomized controlled trials have been reported. However, safety efficacy of laparoscopic compared with open has not demonstrated sufficiently, especially after preoperative chemoradiotherapy low cancer. Objective: The aim this study was to investigate hypothesis that anterior resection safe effective when approach locally advanced mid or neoadjuvant chemoradiotherapy. Patients methods: A...

10.21608/amj.2020.91611 article EN Al-Azhar Medical Journal 2020-07-01
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