Steven Lin

ORCID: 0000-0003-2632-2086
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About
Contact & Profiles
Research Areas
  • Craniofacial Disorders and Treatments
  • Cleft Lip and Palate Research
  • Cerebrovascular and Carotid Artery Diseases
  • History of Medical Practice
  • Intracranial Aneurysms: Treatment and Complications
  • Acute Ischemic Stroke Management
  • Congenital Anomalies and Fetal Surgery
  • Parasitic infections in humans and animals
  • HIV Research and Treatment
  • Growth Hormone and Insulin-like Growth Factors
  • Neuropeptides and Animal Physiology
  • Nuclear Receptors and Signaling
  • Vascular Malformations Diagnosis and Treatment
  • Neurosurgical Procedures and Complications
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Amoebic Infections and Treatments
  • Advanced biosensing and bioanalysis techniques
  • Medical and Biological Sciences
  • Genetic and Kidney Cyst Diseases
  • Stroke Rehabilitation and Recovery
  • Hypothalamic control of reproductive hormones
  • Venous Thromboembolism Diagnosis and Management
  • Medical Imaging Techniques and Applications
  • Advanced MRI Techniques and Applications
  • Infectious Diseases and Tuberculosis

Medical University of South Carolina
2023-2024

Neurological Surgery
2023

University of South Carolina
2020-2022

University of Florida
2020

University of Kentucky
2020

Johns Hopkins Hospital
2008

INTRODUCTION: Magnetic Resonance Imaging’s (MRI) of the spine in pediatric population often require extended scan times and anesthesia to maximize compliance. Previous studies have demonstrated that fast-sequence brain MRIs are efficacious, efficient, present minimal risk patients. However, data on their use setting spinal pathology this is lacking. METHODS: All administered patients 2023 at our institution were assessed. Indications length minutes retrospectively recorded. To assess effects...

10.1227/neu.0000000000003360_301 article EN Neurosurgery 2025-03-14

Dysregulation of dopamine neurotransmission has been linked to the development human immunodeficiency virus (HIV)-associated neurocognitive disorder (HAND). To investigate mechanisms underlying this phenomenon, study used an inducible HIV-1 transactivator transcription (Tat) transgenic (iTat-tg) mouse model, which demonstrates brain-specific Tat expression induced by administration doxycycline. We found that induction in iTat-tg mice for either 7 or 14 days resulted a decrease (∼30%) Vmax...

10.1124/jpet.120.266023 article EN Journal of Pharmacology and Experimental Therapeutics 2020-05-27

Background and Purpose Outcomes following mechanical thrombectomy (MT) are strongly correlated with successful recanalization, traditionally defined as modified Thrombolysis in Cerebral Infarction (mTICI) ≥2b. This retrospective cohort study aimed to compare the outcomes of patients low Alberta Stroke Program Early Computed Tomography Score (ASPECTS; 2–5) who achieved mTICI 2b versus those 2c/3 after MT.Methods utilized data from Thrombectomy Aneurysm Registry (STAR), which combined...

10.5853/jos.2023.02292 article EN cc-by-nc Journal of Stroke 2024-01-31

Dysregulation of dopaminergic transmission induced by the HIV-1 transactivator transcription (Tat) has been implicated as a central factor in development associated neurocognitive disorders (HAND). We have demonstrated that tyrosine470 residue human dopamine transporter (hDAT) plays critical role Tat-hDAT interaction. Based on computational modeling predictions, present study sought to examine mutational effects tyrosine467 norepinephrine (hNET), corresponding hDAT tyrosine470, Tat-induced...

10.1371/journal.pone.0275182 article EN cc-by PLoS ONE 2022-09-28

CASE REPORT A 12-year-old boy with a medical history of constipation presented 6 months’ hematochezia and 3 weeks’ headaches, diarrhea, fatigue, dizziness, unsteady gait. Initial workup was significant for pancytopenia (white blood cell count: 3.4 K/cumm, hemoglobin: 5.9 gm/dL, platelet 117 K/cumm) elevated inflammatory marker (erythrocyte sedimentation rate: 51 mm/h) normal coagulation profile. Head computed tomography scan normal. Abdominal ultrasound revealed 2 cystic lesions within the...

10.14309/crj.0000000000001265 article EN cc-by-nc-nd ACG Case Reports Journal 2024-02-01

This case report presents a rare complication of hepatic cystic echinococcosis in 12-year-old Latino male, residing nonendemic region, who developed long-term sequelae portal vein thrombosis accompanied by the emergence hyper-vascular sigmoid colon mass. Portal involvement is exceedingly uncommon, with limited documented cases. The presentation patient included intermittent hematochezia, abdominal pain, and fatigue. Imaging revealed liver cysts chronic cavernous transformation, resulting...

10.1002/jpr3.12066 article EN cc-by JPGN Reports 2024-03-19

Definitive diagnosis of Craniosynostosis (CS) with computed tomography (CT) is readily available, however, exposure to ionizing radiation often a hard stop for parents and practitioners. Lowering head CT helps mitigate risks improves diagnostic utilization. The purpose the study quantify from in patients CS using ‘new’ (ultra-low dose) protocol; compare prior standard summarize published reports on cumulative doses pediatric scans utilizing other low-dose protocols. A retrospective was...

10.24294/irr.v7i1.2218 article EN Imaging and Radiation Research 2023-08-15

Definitive diagnosis of Craniosynostosis (CS) with computed tomography (CT) is readily available, however, exposure to ionizing radiation often a hard stop for parents and practitioners. Lowering head CT helps mitigate risks improves diagnostic utilization. The purpose the study quantify from in patients CS using ‘new’ (ultra-low dose) protocol; compare prior standard summarize published reports on cumulative doses pediatric scans utilizing other low-dose protocols. A retrospective was...

10.24294/irr.v6i1.2218 article EN Imaging and Radiation Research 2023-08-15

Endovascular treatment (EVT) of small anterior communicating artery (ACoA) aneurysms accompanies a high risk intraprocedural rupture (IR) because anatomic location and aneurysm orientation. In this study, we aimed to investigate the safety efficacy EVT for ACoA in contemporary cohort.ACoA treated at Medical University South Carolina between April 2012 March 2022 were retrospectively analyzed. Periprocedural baseline characteristics, size, clinical radiological outcomes collected. Aneurysms...

10.1227/neu.0000000000002771 article EN Neurosurgery 2023-12-05

Definitive diagnosis of Craniosynostosis (CS) with computed tomography (CT) is readily available, however, exposure to ionizing radiation often a hard stop for parents and practitioners. Lowering head CT helps mitigate risks improves diagnostic utilization. The purpose the study quantify from in patients CS using ‘new’ (ultra-low dose) protocol; compare prior standard summarize published reports on cumulative doses pediatric scans utilizing other low-dose protocols. A retrospective was...

10.24294/irr.v6i2.2218 article EN Imaging and Radiation Research 2023-08-15
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