A5050986359- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Noise Effects and Management
- Health, Environment, Cognitive Aging
- Urban Heat Island Mitigation
- Urban Green Space and Health
- Advanced Chemical Sensor Technologies
- Cardiovascular Disease and Adiposity
- Carcinogens and Genotoxicity Assessment
- Antioxidant Activity and Oxidative Stress
- Angiogenesis and VEGF in Cancer
- Air Quality Monitoring and Forecasting
- Public Health Policies and Education
- Environmental Justice and Health Disparities
- Occupational and environmental lung diseases
- Alcohol Consumption and Health Effects
- Obesity and Health Practices
- Racial and Ethnic Identity Research
- Food Safety and Hygiene
- Health and Lifestyle Studies
- Child Nutrition and Water Access
- Nutritional Studies and Diet
- Birth, Development, and Health
- Environmental and Social Impact Assessments
- Land Use and Ecosystem Services
University of Louisville
2012-2023
National Environmental Health Association
2021
American Public Health Association
2017-2018
Baylor College of Medicine
2015
University of Alabama at Birmingham
2015
Johns Hopkins University
2015
Background Acrolein is a reactive aldehyde present in high amounts coal, wood, paper, and tobacco smoke. It also generated endogenously by lipid peroxidation the oxidation of amino acids myeloperoxidase. In animals, acrolein exposure associated with suppression circulating progenitor cells increases thrombosis atherogenesis. The purpose this study was to determine whether humans increased cardiovascular disease ( CVD ) risk. Methods Results assessed 211 participants Louisville Healthy Heart...
Background Exposure to green vegetation has been linked positive health, but the pathophysiological processes affected by exposure remain unclear. To study relationship between greenness and cardiovascular disease, we examined association residential biomarkers of injury disease risk in susceptible individuals. Methods Results In this cross‐sectional 408 individuals recruited from a preventive cardiology clinic, measured participant blood urine. We estimated satellite‐derived normalized...
Benzene is a ubiquitous, volatile pollutant present at high concentrations in toxins (e.g. tobacco smoke) known to increase cardiovascular disease (CVD) risk. Despite its prevalence, the effects of benzene have rarely been studied. Hence, we examined whether exposure associated with increased CVD The mice were assessed by direct inhalation, while humans was 210 individuals mild risk measuring urinary levels metabolite trans,trans-muconic acid (t,t-MA). Generalized linear models used assess...
Residential proximity to greenness is associated with a lower risk of cardiovascular disease (CVD) and all-cause mortality. However, it unclear whether the beneficial effects are linked reduction in ambient air pollutants. We measured arterial stiffness 73 participants moderate high CVD risk. Average levels PM2.5 ozone were calculated from local monitoring stations. was estimated using satellite-derived normalized difference vegetation index (NDVI) for 200-m 1-km radius around each...
Residential proximity to vegetation and plants is associated with many health benefits, including reduced risk of cardiovascular disease, diabetes mental stress. Although the mechanisms by which greenness affects remain unclear, have been shown remove particulate air pollution. However, association between residential-area exposure volatile organic chemicals (VOCs) has not investigated. We recruited a cohort 213 non-smoking individuals estimated peak, cumulative, contemporaneous greenery...
Previous studies have shown that residential proximity to a roadway is associated with increased cardiovascular disease risk. Yet, the nature of this association remains unclear, and its effect on individual risk factors has not been assessed. The objective study was determine whether roadways influences systemic inflammation levels circulating angiogenic cells.In cross-sectional study, factors, blood C-reactive protein, 15 antigenically defined cell populations were measured in participants...
Climate change is today’s greatest public health threat.1 As the nation’s leading voice in health, American Public Health Association (APHA) has demonstrated an enduring commitment to climate as a issue. far back mid-1920s, AJPH reported on impacts of change.2–4 Shaping development future organizational efforts, APHA members created organization’s first policy statement 1995 (updated 2007 and 2015). continued bring attention making it theme National Week 2008. Since then, evidence change’s...
Key Takeaways Water systems can positively influence public well‐being by teaming up with health agencies. Two case studies are presented that show how this collaborative work happen at a local level. In the United States, Lead and Copper Rule Revisions open way for stronger communications across water sectors.
Introduction: Cardiovascular disease (CVD) is the leading cause of death from environmental exposures. Although exposure to particulate matter ≤2.5μm (PM 2.5 ) an established risk factor for CVD, contribution other hazardous pollutant CVD less clear. Hypothesis: We assessed hypothesis that volatile organic compounds (VOCs) are associated with blood pressure in 778 nonsmokers Jackson Heart Study (JHS), a large, community based observational study African Americans tri-county Jackson, MS area....
Background and Hypothesis: Circulating levels of endothelial progenitor cells have been found to be predictive cardiovascular events mortality. Although the these reflect overall disease (CVD) risk, studies assessing their association with major CVD factors - hypertension, dyslipidemia diabetes yielded inconsistent results mechanisms contributing EPC depletion remain unknown. We hypothesized that occurring in is mediated part by hyperglycemia or insulin resistance. Methods: were measured...
Benzene is a ubiquitous environmental pollutant abundant in plastics, petroleum products and cigarette smoke. Although hematopoietic hepatic toxicity of benzene has been extensively studied, little known about the effect on cardiovascular health. In this study, we assessed exposure cohort 210 participants with moderate to high CVD risk by measuring urinary metabolite - trans, trans-muconic acid (t,t-MA). After adjusting for confounding variables observed 9% decrease circulating levels both...
Circulating levels of vascular progenitor cells (VPCs) have been suggested to be reflective cardiovascular disease (CVD) risk. However, VPCs are a heterogeneous population containing with different angiogenic potential, and it is not clear which specific cell types associated CVD risk factors. We evaluated the relationship between factors using antigenically-defined VPC sub-populations or without validated potential. populations were measured in 240 high adults enrolled Louisville Healthy...