- Botulinum Toxin and Related Neurological Disorders
- Neurological disorders and treatments
- Trigeminal Neuralgia and Treatments
- Migraine and Headache Studies
- Parkinson's Disease and Spinal Disorders
- Neurological and metabolic disorders
- Neurological Disorders and Treatments
- Facial Nerve Paralysis Treatment and Research
- Facial Rejuvenation and Surgery Techniques
- Stroke Rehabilitation and Recovery
- Dermatologic Treatments and Research
- Sympathectomy and Hyperhidrosis Treatments
- Hereditary Neurological Disorders
First Pavlov State Medical University of St. Petersburg
2017-2025
Objective. To evaluate effect of long-term BTA treatment on cervical dystonia (CD) symptoms control and patient satisfaction with botulinum therapy in real life setting. Material methods. A total 1050 patients took part the international observational study INTEREST IN CD2, analysis included data from 995 (overall population), which 56 were enrolled In Russia. CD clinical assessment was performed at baseline days injections using TWSTRS scale tremor component Tsui scale. Patient evaluated...
To access the efficacy and safety of first Russian botulinum toxin type A (Relatox) as a headache prophylaxis in adult with chronic migraine (CM).The randomized, one-blind, multicenter, active-controlled, parallel-group trial study involved 209 patients CM aged from 19 to 65 years. The were randomized injections - Relatox (n=101) or onabotulinumtoxinA Botox (n=108). duration was 16 weeks, which included five visits every 4 weeks. injected once into seven muscle groups head neck at dose...
Evaluation of the safety and effectiveness Relatox, botulinum toxin type A in patients with focal spasticity (FS) upper limb as a result cerebrovascular accident (CVA) or traumatic brain injury (TBI).
The study was aimed to evaluate the efficacy and safety of injections botulinum toxin typeA (BTA) in neck muscles under electromyographic control without it reduce head tremor, muscle tone dystonic postures, as well pain patients with cervical dystonia (CD). 49 CD tremor who received BTA were examined. 33 (67 %) Dysport an average dose 695 (627; 762) units, 15 (31 Xeomin 262 (227; 297) units 1 (2 patient 300 Botox. 16 (33 EMGcontrol. level symptoms before 4 weeks after treatment measured by...
Objective : to evaluate the efficacy and safety of botulinum toxin type A (BTA) injections into neck muscles reduce dystonic postures, head tremor, pain syndrome in patients with cervical dystonia (CD) within first 8 cycles treatment. Patients methods. The investigation included 76 (26 (34%) men 50 (66%) women) CD who were given BTA for time. All received at least one cycle therapy. At same type, 18 these 4 36 had cycles. Injections when symptoms recurred or increased patient needed be...
Нemimasticatory spasm (HMS) is a rare disorder of the nervous system, in which there are unilateral, violent spasms masticatory muscles innervated by motor portion trigeminal nerve. The causes HMS remain largely unexplored, but microvascular compression most likely. Anticonvulsants, surgical treatment and botulinum therapy can be applied for HMS. We presented clinical case 38-year-old woman who had been suffering from this disease 18 years. diagnosis was established only 10 years after first...
To access the effect of Relatox, first Russian botulinum toxin type A, in patients with chronic migraine (CM) and medication overuse (MO).In phase IIIb single-blind randomized multicenter active-controlled parallel-group study, CM were to once intramuscular injections Relatox (n=101) or onabotulinumtoxin A - Botox (n=108). This subgroup analysis evaluated percentage who transition from non status baseline; mean changes number headache days, acute intakes intensity, proportion had a ≥50%...