A5082492932- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Neurological Disorders and Treatments
- Parkinson's Disease and Spinal Disorders
- Genetic Neurodegenerative Diseases
- Stroke Rehabilitation and Recovery
- Neurological Disease Mechanisms and Treatments
- Healthcare Systems and Public Health
- Chemical Reactions and Isotopes
- Gallbladder and Bile Duct Disorders
- Cerebral Palsy and Movement Disorders
- Sphingolipid Metabolism and Signaling
- Sympathectomy and Hyperhidrosis Treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cardiac Health and Mental Health
- Inflammatory mediators and NSAID effects
- Biliary and Gastrointestinal Fistulas
- Ginkgo biloba and Cashew Applications
- Blood Pressure and Hypertension Studies
- Obsessive-Compulsive Spectrum Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Family Support in Illness
- Psychological Treatments and Disorders
- Cardiac Imaging and Diagnostics
St.Petersburg V.M.Bekhterev Psychoneurological Research Institute
2004-2024
Integra (Russia)
2024
Research Medical Center
2017-2024
Ministry of Health of the Russian Federation
2017
Federal Almazov North-West Medical Research Centre
2010
Institute of Cardiology
2004
To enhance the efficacy and safety of nonsteroidal anti-inflammatory drugs (NSAIDs), a class essential medications used to treat acute chronic pain, is an important urgent task. For its solution, in 2015 Russian experts provided an NSAID selection algorithm based on assessment risk factors (RFs) for drug-induced complications and on prescription with least negative effect gastrointestinal tract cardiovascular system. The PRINCIPLE project was implemented test effectiveness this algorithm....
Evaluation of the safety and effectiveness Relatox, botulinum toxin type A in patients with focal spasticity (FS) upper limb as a result cerebrovascular accident (CVA) or traumatic brain injury (TBI).
COVID-19 infection is a significant and poorly understood problem of modern world medicine. As the virus spreads, data on clinical picture disease damage to nervous system are accumulating. Symptoms such as fatigue, anxiety, depression, sleep disturbances many other neurological somatic symptoms often recorded, persist for long time even after acute infectious stage has been stopped, make it difficult patient fully recover. These occur with mild months. One most common disabling post-COVID...
Spastic paresis is a complex condition associated with damage to the upper motor neurons, typically caused by cerebral palsy, multiple sclerosis, stroke or trauma. Despite substantial impact on patients’ independence and burden caregivers, there lack of consensus optimal management this patient journey remains unclear. A group physicians, experienced in spasticity management, recently convened objective analysing from care pathway perspective different geographical regions under conditions...
Objective : to evaluate the efficacy of antiparkinsonian drugs different groups considering frequency-amplitude characteristics in correction tremulous hyperkinesis Parkinson's disease (PD) using tremorography. Material and methods . 172 patients with a confirmed diagnosis PD were observed. Taking into account age contraindications, divided four receiving one monotherapy: dopamine receptor agonists (ADR; pramipexole), levodopa (Tidomet forte), anticholinergics (biperiden), amantadines...
Актуальность проблемы когнитивных нарушений и астенических состояний только увеличивается, особенно в последние годы, на фоне эпидемии COVID-19. В этой связи вызывает интерес использование действующих веществ или их комбинаций для помощи пациентам с астенией когнитивными нарушениями. Соединения холина экстракт гинкго билоба, каждый компонент отдельности, давно известны своими прокогнитивными антиастеническими эффектами. Тем более интересно рассмотреть потенциальную пользу применения...
Chronic progressive cerebrovascular pathology is a powerful disabling factor in modern society. cerebral ischemia based on microcirculation and neuroinflammation problems, which are mutually potentiating pathogenetic aspects. As search for pathogenetically oriented targeted therapy, great attention paid to capillary disease, oxidative stress brain tissue the issues of suppressing neuroinflammation. The article presents materials experimental clinical studies Ginkgo biloba extract choline, as...
Depression and sialorrhea are among the most common distressing non-motor symptoms of Parkinson's disease at all stages disease. They impair patient's quality life ability to function mutually reinforce each other in context comorbidity. To date, exact pathophysiological mechanisms underlying development these conditions contribution dopaminergic regulatory system dysfunctions their unclear. Although there established methods treat both depression sialorrhea, is still no recommended...
One of the important areas modern neurology is movement disorders, due to their negative impact on daily activity and quality life patients. Dystonia third most common extrapyramidal disease. Often, dystonia accompanied by trembling hyperkinesis, however, known data dystonic tremor are scattered not systematized, its fixation causes difficulties lack clear tremorographic characteristics. Many issues prevalence, pathophysiology, differential diagnosis with other types tremor, as well...
Background: Essential tremor is one of the most prevalent extrapyramidal disorders, while treatment efficacy in such patients remains low. Clinical polymorphism essential requires a differentiated approach, that should be implemented with consideration objective parameters. Aim: To study based on tremorography. Materials and methods: We followed up 85 (mean age, 69.05±1.2 years) who were treated anticonvulsants as monotherapy (primidone or topiramate), combination non-selective beta-blockers...
Objective: The study addresses the impact of different criteria left ventricular hypertrophy (LVH) and concentric remodelling to prevalence patterns in hypertension. ASE 2005 recommendations significantly reduced threshold for LVH detection relative wall thickness (RWT) geometry pattern. Design Methods: We examined 734 patients with essential hypertension 9EH) who had no concomitant diseases medication. Echocardiography was performed analyzed by one observer. mass index (LVMI) RWT were...