A5084956170- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Corrosion Behavior and Inhibition
- Multicomponent Synthesis of Heterocycles
- Chemical Synthesis and Analysis
- Concrete Corrosion and Durability
- Click Chemistry and Applications
- Synthesis and Biological Evaluation
- Chemical Synthesis and Reactions
- Hydrogen embrittlement and corrosion behaviors in metals
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Asymmetric Synthesis and Catalysis
- Catalytic Cross-Coupling Reactions
- Synthesis and biological activity
- Crystallography and molecular interactions
- Synthesis and Characterization of Heterocyclic Compounds
- Microwave-Assisted Synthesis and Applications
- Nanocluster Synthesis and Applications
- Ionic liquids properties and applications
- Synthesis and pharmacology of benzodiazepine derivatives
- Cancer therapeutics and mechanisms
- Cyclopropane Reaction Mechanisms
- Metal and Thin Film Mechanics
- Carbohydrate Chemistry and Synthesis
- Coordination Chemistry and Organometallics
Universidad Nacional Autónoma de México
2018-2021
Universidad Autónoma Metropolitana
2013-2020
Instituto Politécnico Nacional
2005-2019
Center for Research and Advanced Studies of the National Polytechnic Institute
2006-2019
The preparation and full characterization of a variety mono- ([L1-H]), di- ([L2-H2], [L2A-H2]), tri- ([L3-H3]) 1,2,3-triazolium salts constructed form "clicked" hydroxybenzene derivatives are reported. Deprotonation with potassium hexamethyldisilazide, followed by in situ metalation, allowed for the synthesis series (L1·[M]), (L2·[M]2, L2·[M]2), trinuclear (L3·[M]3) group 9–11 (M = [Rh(CO)2Cl], [Pd(allyl)Cl], [AuCl]) triazol-5-ylidene metal complexes. In solution, all complexes feature...
An efficient one-pot synthesis of 1,2,3-triazole derivatives dihydropyrimidinones has been developed using two multicomponent reactions. The aldehyde-1,2,3-triazoles were obtained in good yields from situ-generated organic azides and O-propargylbenzaldehyde. target heterocycles synthesized through the Biginelli reaction which reacted with ethyl acetoacetate urea presence Ce(OTf)3 as catalyst. corrosion inhibition steel grade API 5 L X52 1 M HCl by compounds was investigated electrochemical...
A series of new mono-1,2,3-triazole derivatives pyrimidine nucleobases were synthesized by one-pot copper(I)-catalyzed 1,3-dipolar cycloaddition reactions between N-1-propargyluracil and thymine, sodium azide several benzyl halides. The desired heterocyclic compounds obtained in good yields characterized NMR, IR, high resolution mass spectrometry. These investigated as corrosion inhibitors for steel 1 M HCl solution, using electrochemical impedance spectroscopy (EIS) technique. results...
Ten 1,4-disubstituted 1,2,3-triazoles were synthesized from one of 1-(azido-methyl)benzene, 1-(azidomethyl)-4-fluorobenzene, 1-(azidomethyl)-4-chlorobenzene, 1-(azidomethyl)-4-bromobenzene or 1-(azidomethyl)-4-iodobenzene, generated in situ sodium azide and the corresponding benzyl halide, dipropargyl uracil thymine. Optimal experimental conditions established for conventional click chemistry. The corrosion inhibiting properties some these compounds, which determined by means an...
A series of <italic>O</italic>- and <italic>S</italic>-functionalized triazolium salts display high performance in the Baylis–Hillman addition allow one-pot formation MIC-transition metal complexes.
Cu(Al)O mixed oxide promotes the formation of 1,2,3-triazoles from an alkyne–azide cycloaddition reaction with excellent yields using EtOH–H<sub>2</sub>O mixture as solvent under microwave heating.
This report describes the application of three chiral bicyclic diamines as organocatalysts in enantioselective Biginelli reaction.The product this reaction is 3,4-dihydropyrimidin-2(1H)-one (DHPM), a heterocycle great importance owing to its interesting biological activity.It was found that (1S,4S)-2,5-diazabicyclo[2.2.1]heptane•2HBr (1) and N-methylated derivative 2 effectively catalyze between ethyl acetoacetate, representative aromatic aldehydes, urea afford expected DHPMs good yields...
The phenol-derived triazoles beginning at 10 ppm show excellent inhibition against corrosion when immersed in 1 M HCl.
Abstract Thirty‐seven (most of them novel) chiral derivatives (1 S ,4 )‐2,5‐diazabicyclo[2.2.1]heptane ( 2 – 36 , 38 39 ) were prepared from )‐ trans ‐4‐hydroxyproline. A selection these ligands examined as potential in the preparation catalysts for enantioselective addition diethylzinc to aldehydes and Lewis acid activators asymmetric Diels–Alder reaction. In former system, diamine 30 induced up 92 % enantiomeric excess formation )‐phenyl ethyl carbinol, whereas case cycloaddition reaction...
A series of new mono- and bis-1,2,3-triazole derivatives 2-benzimidazolethiol were synthesized by three-component copper(I)-catalyzed 1,3-dipolar cycloaddition. The desired heterocycles obtained in good yields fully characterized. corrosion inhibition efficiency heterocyclic compounds was investigated on steel grade API 5L X52 1 M HCl using electrochemical impedance spectroscopy. results revealed that these organic show promising properties for the acidic media.
An efficient and practical methodology for the microwave-assisted synthesis of 2-benzimidazolethiol from 1,2-benzenediamine carbon disulfide using reconstructed hydrotalcite is described. The corresponding mono- dialkylated derivatives were obtained generally in good to excellent yields after short reaction times. Reconstructed proved be an reusable heterogeneous base alkylation reactions.
A simple and efficient protocol for the synthesis of β-nitrostyrenes has been achieved by use sulfated zirconia–secondary amine cooperative systems.
The use of microwave heating is a valuable tool for synthetic chemists. Being able to reduce reaction times and increase product yield, this methodology offers organic chemists the potential optimize processes. Additionally, microwave-assisted reactions provide more environmentally friendly conditions. In report, we describe results in optimization several employed synthesis various chiral molecules such as heterocycles, β-amino acids, β-peptides, among others.
The synthesis is reported of (±)-5-oxo-1-phenylpyrazolidine-3-carboxylic acid, (±)-3, via nucleophilic addition phenylhydrazine to dimethyl maleate, followed by cyclization the resulting hydrazine-diester.The resolution (±)-3 was achieved diastereomeric salts employing (R)-and (S)-α-methylbenzylamine as resolving agent.Preferential crystallization like (R,R)-and (S,S)-salts allowed isolation desired enantiomerically pure (S)-target compounds in up 87-89 % theoretical yield.An X-ray structure...