Laura Samples

ORCID: 0000-0003-2680-0244
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About
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Research Areas
  • Chronic Lymphocytic Leukemia Research
  • CAR-T cell therapy research
  • Lymphoma Diagnosis and Treatment
  • CNS Lymphoma Diagnosis and Treatment
  • Health Systems, Economic Evaluations, Quality of Life
  • Childhood Cancer Survivors' Quality of Life
  • Frailty in Older Adults
  • Breast Lesions and Carcinomas
  • PI3K/AKT/mTOR signaling in cancer
  • Advanced Breast Cancer Therapies
  • Viral Infectious Diseases and Gene Expression in Insects
  • Telemedicine and Telehealth Implementation
  • Mobile Health and mHealth Applications
  • Insect Resistance and Genetics
  • Methemoglobinemia and Tumor Lysis Syndrome
  • Cancer and Skin Lesions
  • Healthcare Systems and Technology
  • Medication Adherence and Compliance
  • Acute Lymphoblastic Leukemia research
  • Acute Myeloid Leukemia Research
  • Forensic Toxicology and Drug Analysis
  • Breast Cancer Treatment Studies

Fred Hutch Cancer Center
2023-2025

University of Washington
2017-2024

University of Washington Medical Center
2024

VA Puget Sound Health Care System
2020

Washington State University Vancouver
2012

Abstract Although Bruton tyrosine kinase inhibitors (BTKis) are generally well tolerated and less toxic than chemotherapy alternatives used to treat lymphoid malignancies, BTKis like ibrutinib have the potential cause new or worsening hypertension (HTN). Little is known about optimal treatment of BTKi-associated HTN. Randomly selected patients with malignancies on a BTKi antihypertensive drug(s) at least 3 months follow-up data were sorted into 2 groups: those diagnosed HTN before initiation...

10.1182/bloodadvances.2023011569 article EN cc-by-nc-nd Blood Advances 2024-02-05

7571 Background: Burkitt lymphoma (BL) is a rare, but highly aggressive B-cell associated with especially poor outcomes in patients relapsed/refractory disease. Multiple CD19 chimeric antigen receptor (CAR) T-cell products have been FDA approved to treat non-Hodgkin the second-line setting, however little known about CAR responses BL. This multicenter study aims assess real-world among BL treated therapy across United States. Methods: multicenter, retrospective chart review was conducted by...

10.1200/jco.2023.41.16_suppl.7571 article EN Journal of Clinical Oncology 2023-06-01

Background: Clinical Video Telemedicine to Home (CVTH) allows primary care clinicians conduct clinical encounters with patients in remote locations through a secure synchronous video connection, offering improved access and increased patient satisfaction. Introduction: Although implementation of CVTH continues grow, little is known about clinician perceptions applicability or utilization barriers. We assessed provider attitudes perceived barriers toward visits at the Seattle Veterans Affairs...

10.1089/tmj.2020.0045 article EN Telemedicine Journal and e-Health 2020-07-07

PURPOSE Venetoclax is the standard of care for chronic lymphocytic leukemia (CLL)/small lymphoma (SLL) but requires intensive monitoring optimal safety. Clinical relevance in practice unknown, especially patients with low or intermediate risk tumor lysis syndrome (TLS). PATIENTS AND METHODS A retrospective review was conducted to determine clinical significance TLS during ramp-up CLL/SLL. Patients receiving abbreviated ramp-up, trials, concurrent Bruton tyrosine kinase inhibitors were...

10.1200/op.24.00416 article EN JCO Oncology Practice 2024-11-18

e18301 Background: Oral targeted agents (OTAs) are rapidly changing the management of B-cell malignancies (BCM) and introducing challenges in prescribing practices communication between patients, their clinicians, pharmacists. Emerging data suggests dose interruptions impair OTA efficacy BCM. However, infrastructure to ensure best may be outstripped by increasing use some clinics. We evaluated adherence OTAs for BCMs at Veterans Affairs Puget Sound Health Care System identify opportunities...

10.1200/jco.2019.37.15_suppl.e18301 article EN Journal of Clinical Oncology 2019-05-20
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