A5018185008- Nutrition and Health in Aging
- Frailty in Older Adults
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- Body Composition Measurement Techniques
- Bone health and osteoporosis research
- Alzheimer's disease research and treatments
- Health and Well-being Studies
- Blood Pressure and Hypertension Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Bone Metabolism and Diseases
- Clinical Nutrition and Gastroenterology
- SARS-CoV-2 and COVID-19 Research
- Pelvic floor disorders treatments
- Antioxidant Activity and Oxidative Stress
- Cardiovascular Health and Disease Prevention
- Bone health and treatments
- Child Nutrition and Feeding Issues
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Dialysis and Renal Disease Management
- Regulation of Appetite and Obesity
- Vitamin D Research Studies
- Neurological Disorders and Treatments
- Folate and B Vitamins Research
Istinye University
2024-2025
Gaziosmanpaşa Taksim Eğitim ve Araştırma Hastanesi
2025
Istanbul University-Cerrahpaşa
2015-2024
Istanbul University
2012-2018
Turkish Society of Hematology
2016
Orient-Institut Istanbul
2015
Bridge University
2015
The aim of this study is to investigate the effect oral l-Glutamine supplementation on hospitalization time, need for intensive care unit and Coronavirus Disease-19 (Covid-19) mortality.The included 30 Covid-19 patients using who did not use with similar age, gender clinical status. Diagnostic tests, laboratory examinations, findings computed thorax tomography imaging were evaluated.Hospitalization time was 10.4 ± 1.9 days in without L-Glutamine group 8.9 1.8 (p = 0.005). In group, four...
Objectives: The aim of this study is to evaluate the relationship miR-21, nitric oxide (NOx) and endothelial synthase (eNOS) with subclinical atherosclerosis in carotid arteries by measuring intima media thickness (CIMT) patients hypertension healthy controls. Design Methods: A total 28 hypertensive controls were enrolled. MiR-21 expression was analyzed quantitative reverse transcription-PCR NOx, eNOS levels measured ELISA assay. CIMT evaluated ultrasonography ≥ 0.8 mm accepted as increased...
White coat hypertension (WCH) is a high cardiovascular risk condition, and fundamental understanding of the cause pathophysiology disorder still lacking. Recent studies demonstrated that microRNAs (miRNAs) are involved in hypertension; however, roles miRNAs WCH not known. The expressions selected 10 were investigated independently plasma samples from 30 (HT) patients, normotensive (NT) subjects. MiR-21, miR-122, miR-637, let-7e expression levels significantly upregulated HT group compared...
Background and Objectives: This study aims to evaluate neurosurgery consultations for elderly patients during following the COVID-19 pandemic. Materials Methods: included aged 65 older who were hospitalized in non-neurosurgery departments at Istinye University Gaziosmanpasa Medical Park Hospital referred between 1 April 2020 31 May 2024. Patients intensive care unit emergency department excluded. The period from 30 2022 was defined as pandemic period, 2024 post-pandemic period. Results: A...
To recognize the period of exaggerated cytokine response in patients with coronavirus disease 2019 (COVID-19) pneumonia, and to describe clinical outcomes using tocilizumab as a treatment option. The data 12 adult COVID-19 pneumonia who were followed inpatient clinics Biruni University Medical Faculty Hospital (Istanbul, Turkey) retrospectively analyzed. Diagnostic tests, laboratory examinations, findings, computed tomography thorax imaging results evaluated. A dramatic improvement was...
To investigate the relationship between handgrip strength with types of urinary incontinence (UI) and pelvic floor muscle (PFMS) in women.Ninety-two women, who presented to geriatric urology outpatient clinics complaining UI July 2019 February 2020 had indicated undergo urodynamic assessment after basic neurourological evaluation, were included this cross-sectional study. The presence identified by clinical examination studies. Demographic parameters, anthropometric data, comorbidities...
The aim of the present study was to determine systemic levels oxidative stress markers, such as ischemia-modified albumin (IMA), advanced oxidation protein products (AOPP), ferric reducing antioxidant power (FRAP) and prooxidant-antioxidant balance (PAB), clarify redox homeostasis in patients with Alzheimer's disease, compare them mentally healthy persons same age.A total 38 disease (AD) 34 sex- age-matched control subjects were included this study.The had significantly higher AOPP, IMA PAB...
Background Depression is one of the most common mental disorders among older adults and depressive symptoms are strongly associated with adverse health outcomes. We aim to examine whether sarcopenia malnutrition in adults. Methods reviewed hospital records 447 patients (≥65 years) who were admitted outpatient clinics, retrospectively. In addition demographic characteristics, all participants measured for usual gait speed (UGS), handgrip strength (HGS) skeletal muscle mass (SMMI) by using...
OBJECTIVE: To investigate the relationship of sarcopenia with systemic inflammation response index (SIRI), monocyte to high-density lipoprotein ratio (MHR) and platelet parameters in geriatric patients.METHODS: We designed a cross-sectional retrospective study patients presented outpatient clinic for first time.The diagnosis was made accordance EWGSOP2 criteria.SIRI, MHR, mean volume /Platelet count (MPV/Plt), distribution width (PDW/Plt), platelet/lymphocyte (PLR) were calculated from...
Alteration in energy expenditure or metabolism is the most accused risk issue for onset and course of neurodegenerative cognitive disorders. Neuropeptides are suggested to be related with learning memory. Phoenixin (PNX) recently reported neuropeptide we aimed compare plasma level people subjective memory complaints, patients mild impairment, Alzheimer's disease (AD).
Abstract In this study, we report a large family cluster consisting of 29 genetically related patients hospitalized with coronavirus disease‐2019 (COVID‐19). We sought to determine the clinical characteristics relevant course COVID‐19 by comparing unrelated SARS‐CoV‐2 infection so that presence potential determinants disease severity, other than traditional risk factors previously reported, could be investigated. Twenty‐nine patient files were investigated in group 1 and 2 was created 52...
Serum fibroblast growth factor (FGF)-19 and FGF-21 levels have been reported to be associated with muscle hemostasis. This study aims explore the relationship between of these markers sarcopenia.In our single-center, cross-sectional study, patients over 65 years old presenting geriatric outpatient clinic were included. Patients secondary sarcopenia excluded. The Strength-Assistance walking-Rising from a chair-Climbing stairs Falls (SARC-F) questionnaire was applied all patients. Sarcopenia...
Aging is characterized by appetite loss and cachexia, i.e., factors that contribute to malnutrition. An inflammation marker, neutrophil-to-lymphocyte ratio (NLR), a significant prognostic predictor of many geriatric syndromes. We aim determine the association between NLR malnutrition.We designed retrospective study on hospitalized patients in unit university hospital January 2019 2021. Demographic data, chronic diseases, history smoking, length stay, number drugs, laboratory further...
Matrix metalloproteinases (MMPs) play an important role in bone resorption and are regulated by tissue inhibitors of (TIMPs). We investigated the use MMP2/TIMP2 MMP9/TIMP1 ratios as biomarkers geriatric osteoporosis evaluated relationship between syndromes.This analytical cross-sectional study involved 87 patients (41 with osteoporosis) treated at outpatient clinic a university hospital. The demographic characteristics, comprehensive assessment scores, laboratory findings, mineral density...
Background/aim: We aimed to investigate the factors affecting mortality of patients aged 65 years or older who were hospitalized with diagnosis new coronavirus pneumonia (COVID-19). Materials and methods: This is a retrospective study old COVID-19 in İstanbul University-Cerrahpaşa, Cerrahpaşa Medical Faculty Hospital, between March 11 May 28, 2020. Demographic, clinical, treatment, laboratory data extracted from electronic medical records. used univariate multivariate logistic regression...
Because of the senescence immune system, antibody response to COVID-19 vaccines may differ from older younger adults. The study aim compares titers SARS-CoV-2 IgG patients ≥60 years who received three doses CoronaVac vaccine and those two CoronaVac+1 dose Pfizer-BioNTech after 1 month last vaccination. Patients between March 1, 2021, April 30, did not have disease before first vaccination were negative for antibodies, whose antibodies tested third vaccination, any during follow-up included....