A5009899464- Climate Change and Health Impacts
- Health and Medical Studies
- Prostate Cancer Diagnosis and Treatment
- Cancer therapeutics and mechanisms
- Public Health Policies and Education
- Global Public Health Policies and Epidemiology
- Antibiotics Pharmacokinetics and Efficacy
- Drug Transport and Resistance Mechanisms
- Pluripotent Stem Cells Research
- Prostate Cancer Treatment and Research
- Global Health Care Issues
- Antibiotic Use and Resistance
- 3D Printing in Biomedical Research
- Viral Infections and Vectors
- Neutropenia and Cancer Infections
- Bacterial Identification and Susceptibility Testing
- Mitochondrial Function and Pathology
- Viral Infections and Outbreaks Research
- CRISPR and Genetic Engineering
- Climate Change Communication and Perception
- Sex and Gender in Healthcare
- MRI in cancer diagnosis
- Mosquito-borne diseases and control
- Pancreatic and Hepatic Oncology Research
- Community Health and Development
Leipzig University
2019-2025
University Hospital Leipzig
2022-2024
Klinik und Poliklinik für Neurologie
2023
BIG Direkt Gesund
2021
Planet
2021
London School of Hygiene & Tropical Medicine
2019
Inserm
2013-2018
Université de Strasbourg
1986-2018
Centre National de la Recherche Scientifique
2014-2018
Charles River Laboratories (Germany)
2018
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder caused by limited expansion of CGG repeats in the 5′ UTR FMR1. Two mechanisms are proposed to cause FXTAS: RNA gain-of-function, where sequesters specific proteins, and translation into polyglycine-containing protein, FMRpolyG. Here we developed transgenic mice expressing repeat with or without Expression FMRpolyG pathogenic, while sole expression not. interacts nuclear lamina protein LAP2β disorganizes...
### Summary box A growing chorus of voices are questioning the glaring lack women in COVID-19 decision-making bodies. Men dominating leadership positions global health has long been default mode governing. This is a symptom broken system where governance not inclusive any type diversity, be it gender, geography, sexual orientation, race, socio-economic status or disciplines within and beyond – excluding those who offer unique perspectives, expertise lived realities. only reinforces...
Introduction Effective antimicrobial stewardship programs require data on consumption (AMC) and utilization (AMU) to guide interventions. However, such is often scarce in low-resource settings. We describe the of antibiotics at a large tertiary-level hospital Uganda. Methods In this cross-sectional study Kiruddu National Referral Hospital, we analyzed medicine delivery records for period July 2021 June 2022, accessed 12/08/2022, extract AMC expressed as defined daily doses (DDDs) per 1000...
Pore-size distribution (PSD) is the most critical parameter for size-exclusion virus removal filters. Yet, different dry- and wet-state porometry methods yield pore-size values. The goal of this work to conduct comparative analysis nitrogen gas sorption (NGSP), liquid-liquid cryoporometry with differential scanning calorimetry (CP-DSC) respect characterization regular cross-linked filter paper based on cellulose nanofibers, i.e. mille-feuille filter. filters were further characterized atomic...
In light of global environmental crises and the need for sustainable development, fields public health sciences have become increasingly interrelated. Both require interdisciplinary thinking solutions, which is largely directed by scientific progress documented in peer-reviewed journals. Journal editors play a critical role coordinating shaping what accepted as knowledge. Previous research has demonstrated lack diversity gender geographic representation across disciplines. This study aimed...
Layer-by-layer (LbL) assembled multicomponent films offer the opportunity to control and fine-tune cell attachment behavior on solid surfaces [Layer-by-Layer Films for Biomedical Applications, edited by Picart et al. (Wiley, Weinheim, 2014) El-Khouri al., “Multifunctional layer-by-layer architectures biological applications,” in Functional Polymeric Ultrathin Films, Advincula Knoll 2011), Vol. 1]. At same time, these allow quite detailed physicochemical characterization of static dynamic...
In this study, we deep-sequenced the mtDNA of human embryonic and induced pluripotent stem cells (hESCs hiPSCs) their source found that majority variants pre-existed in used to establish lines. Early-passage hESCs carried few low-load heteroplasmic variants, similar those identified oocytes inner cell masses. The number loads these increased with prolonged culture. study 120 individual early- late-passage revealed a significant diversity at single-cell level increase during time culture are...
Historically, blood-shedding has often been associated with heroic acts of valour. However, menstruation is not praised and cherished in the same way. Rather, shrouded secrecy, stigma, stress, despite being a natural physiological process that occurs quarter global population. Access to availability menstrual hygiene products (MHPs) inadequate for many women, girls, transgender non-binary people, particularly low-income middle-income countries among vulnerable populations (eg, sexual or...
Against the backdrop of civic engagement, such as Fridays For Future movement, expectations were high for 2020 to be a year accelerating commitment climate, biodiversity, and women's rights; marked by plans UN Climate Summit, Convention on Biological Diversity 25th anniversary Beijing Declaration rights. Instead, political agenda was defined COVID-19, which has served an unwelcome, although timely, reminder fundamental interconnectedness environmental, social, economic systems. True recovery...
Background While an estimated 70%–75% of the health workforce are women, this is not reflected in leadership roles most organisations—including global decision-making bodies such as World Health Assembly (WHA). Methods We analysed gender representation WHA delegations Member States, Associate Members and Observers (country/territory), using data from 10 944 75 815 delegation members over 1948–2021. Delegates’ information was extracted WHO documentation. Likely inferred based on prefixes,...
We are next generation leaders coming from the climate justice, medicine and public health, planetary health movements, representing Most Affected People Areas (MAPA), which groups territories disproportionately affected by crisis -women, Indigenous Peoples, racialised people, LGBTQ+ young, those facing social deprivation, Global South.Each time Conference of Parties (COP) United Nations Framework Convention on Climate Change (UNFCCC) is held, our presence sought, faces shown television,...
Planetary health education focuses on the climate and ecological crises their adverse effects. Given acceleration of these crises, nationwide integration planetary into undergraduate graduate education, postgraduate training continuing for all professionals has repeatedly been called for. Since 2019, promoted by several national initiatives in Germany that are summarized this commentary: 1. National Working Group Health Education, 2. Manual 3. Catalog Learning Objectives Competency-Based...
The global spread of antimicrobial resistance (AMR) poses an increasing challenge for clinicians in Uganda, where microbiological diagnostics are not routinely available or accessible. aim this study was to determine pathogen prevalence and antibiotic patterns patients with wound infections following trauma at a national referral hospital Kampala, Uganda. In addition, the suitability currently used empirical treatment options setting evaluated. This prospective, observational analysed...