Yuanyuan Shen

ORCID: 0000-0003-2702-8073
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About
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Research Areas
  • Nanoparticle-Based Drug Delivery
  • Nanoplatforms for cancer theranostics
  • RNA Interference and Gene Delivery
  • Advanced biosensing and bioanalysis techniques
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Coronary Interventions and Diagnostics
  • Curcumin's Biomedical Applications
  • Dendrimers and Hyperbranched Polymers
  • Microencapsulation and Drying Processes
  • Polysaccharides Composition and Applications
  • Mycotoxins in Agriculture and Food
  • Polysaccharides and Plant Cell Walls
  • Nanocomposite Films for Food Packaging
  • Antimicrobial Peptides and Activities
  • Polymer Surface Interaction Studies
  • 3D Printing in Biomedical Research
  • Advanced Drug Delivery Systems
  • Monoclonal and Polyclonal Antibodies Research
  • Pesticide Residue Analysis and Safety
  • Characterization and Applications of Magnetic Nanoparticles
  • Natural Compounds in Disease Treatment
  • Esophageal Cancer Research and Treatment
  • Electrospun Nanofibers in Biomedical Applications
  • Beetle Biology and Toxicology Studies
  • Elasticity and Material Modeling

Institute of Oceanology
2025

First Affiliated Hospital of Anhui Medical University
2016-2024

Anhui Medical University
2016-2024

Wenzhou Medical University
2024

Xuzhou Central Hospital
2023

Shanghai Jiao Tong University
2014-2023

Shandong University
2023

Chinese Academy of Sciences
2023

Changchun Institute of Applied Chemistry
2023

Zhejiang A & F University
2021

A multifunctional anti-cancer nanomedicine based on a biotin-poly(ethylene glycol)-poly(curcumin-dithio dipropionic acid) (Biotin-PEG-PCDA) polymeric nanocarrier loaded with paclitaxel (PTX), magnetic nanoparticles (MNPs) and quantum dots (QDs) is developed. It combines advantageous properties of efficient targeted delivery uptake (

10.1039/c5tb02450a article EN cc-by Journal of Materials Chemistry B 2016-01-01

Tumor-specific disintegratable nanohybrids can penetrate into tumor deep tissue and be eliminated, exhibiting high efficacy for cancer diagnosis treatment.

10.1039/c7mh01071k article EN Materials Horizons 2018-01-01

Abstract Small-molecule chemosensitizers can reverse cancer multidrug resistance (MDR), thus significantly improving the in vitro effect of chemotherapy drugs for MDR cells, however, their vivo effects are not always very good, because they difficult to effectively accumulate tumor and enter same with after systemic administration due individual biopharmaceutical properties. To overcome these limitations, here we study a novel nanoparticular pre-chemosensitizer which be also used as...

10.1038/srep21459 article EN cc-by Scientific Reports 2016-02-15

Abstract Background Feedback is critical to improving practitioners’ clinical practice and professional growth. Although they are still considered junior practitioners, their feedback-seeking experiences have yet be investigated. This study aimed understand the fundamental thoughts of new graduate nurses regarding identify main factors that influence behaviors. Methods Conducting a descriptive phenomenological study, semi-structured in-depth interviews with newly graduated from four...

10.1186/s12912-023-01657-3 article EN cc-by BMC Nursing 2024-01-02

To identify factors associated with job embeddedness from the perspective of retaining new graduate nurses.

10.1111/jan.16289 article EN Journal of Advanced Nursing 2024-06-28

High transparency and durable antifouling surfaces are crucial for Marine applications. However, achieving a long-lasting marine coating that combines both properties high transmittance remains significant challenge. In this study, we present novel high-adhesion, self-healing Slippery Liquid-Infused Porous Surface (SLIPS) with unique three-arm structure, designed from poly(dimethylsiloxane) supramolecular polymer, inspired by the design of natural spider webs. This structure leverages...

10.1021/acsami.5c02695 article EN ACS Applied Materials & Interfaces 2025-04-15

A simple and reliable analytical method for the simultaneous determination of alternariol (AOH), altenuene (ALT), tentoxin (TEN), altenusin (ALS), tenuazonic acid (TeA), monomethyl ether (AME) in grapes was developed by ultra-high-performance liquid chromatography–tandem mass spectrometry (UHPLC-MS/MS). modified QuEChERS (quick, easy, cheap, effective, rugged, safe) procedure with extraction acetonitrile purification sodium chloride (0.5 g) anhydrous magnesium sulfate established to recover...

10.3390/toxins11020087 article EN cc-by Toxins 2019-02-01

Intracellularly degradable, self-assembled amphiphilic biotin-poly(ethylene glycol)-b-poly(curcumin-dithiodipropionic acid) nanoparticles are developed. They display excellent in vivo anticancer efficacy, benefitted from their high tumor-targeted accumulation and stimuli-triggered intracellular drug release. can be loaded with other drugs (e.g., doxorubicin) to exploit the synergy of combinational dual-drug therapy further enhance efficacy. As a service our authors readers, this journal...

10.1002/adhm.201500075 article EN Advanced Healthcare Materials 2015-06-01

Adding μ-opioid receptor agonists to local anesthetics are usually used for labor analgesia, while they associated with pruritus. Kappa opioid (dezocine) widely pain management. Recently, have emerged as a novel type of potent antipruritic agents. The purpose this study was investigate the effects dezocine ropivacaine on epidural analgesia during labor. A total 120 parturients were randomly divided into two groups (60 cases each). group D received 0.1% 0.2 mg/mL control sufentanil 0.4 μg/mL...

10.3389/fphar.2025.1586393 article EN cc-by Frontiers in Pharmacology 2025-04-28
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