A5101585819- Transportation Planning and Optimization
- Collaboration in agile enterprises
- Evacuation and Crowd Dynamics
- Human Mobility and Location-Based Analysis
- Urban Transport and Accessibility
- COVID-19 epidemiological studies
- Infrastructure Maintenance and Monitoring
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Traffic control and management
- Synthesis and Biological Evaluation
- Anesthesia and Neurotoxicity Research
- Infection Control and Ventilation
- Transportation and Mobility Innovations
- Organizational Leadership and Management Strategies
- Business Strategies and Innovation
- Education and Work Dynamics
- Organic Chemistry Synthesis Methods
- Optical measurement and interference techniques
- Synthesis of heterocyclic compounds
- Geomechanics and Mining Engineering
- Cruise Tourism Development and Management
- Intensive Care Unit Cognitive Disorders
- Synthesis and bioactivity of alkaloids
Shandong Provincial Hospital
2025
Shandong First Medical University
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Shandong University
2025
Chengdu University of Technology
2025
Beijing Normal University
2022-2024
Jianghan University
2024
University of Hong Kong
2022-2023
National Institute of Clean and Low-Carbon Energy
2023
Hong Kong University of Science and Technology
2023
To investigate the role and mechanism of catalpol in brain angiogenesis a rat model stroke, effect (5 mg/kg; i.p) or vehicle administered 24 hours after permanent middle cerebral artery occlusion (pMCAO) on behavior, angiogenesis, ultra-structural integrity capillary endothelial cells, expression EPO VEGF were assessed. Repeated treatments with Catalpol reduced neurological deficits significantly improved while increasing levels without worsening BBB edema. These results suggested that might...
Reduced oocyte quality is a key factor in age-related fertility decline, and there are no effective treatments available. The secretome of mesenchymal stem cells (MSC-sec) contains various bioactive factors has the potential to improve quality. This study aimed investigate component molecular mechanism MSC-sec involved improving from aged mice humans. Immunofluorescence chromosome spread were performed effects human umbilical cord-MSC on spindle assembly aneuploidy mouse oocytes....
This study employs an accounting approach to quantitatively assess Chengdu’s ecological value, focusing on agriculture, forestry, animal husbandry, fisheries, climate regulation, water conservation, quality purification, and air improvement. The value of each indicator is calculated visualized using ArcGIS 10.8, with predictions made for four future time intervals. analysis reveals the spatial distribution patterns across Chengdu. results indicate following: (1) From 2015 2019, indicators...
Introduction: Ketamine is commonly used in pediatric anesthesia but recent studies have shown that it could induce neurotoxicity the developing brain.The inflammatory cytokine, tumor necrosis factor α (TNF-α) involved pathogenesis of various types neurodegenerations.In present study, we examined whether TNF-α may regulate ketamine-induced hippocampus neonatal mouse.Material and methods: The vitro organotypic culture hippocampal slices was to investigate gain-of-function loss-of-function...
Abstract Olaquindox (OLA) has been widely used as an animal feed additive in China for decades; however, its toxicity and toxic mechanisms have not well investigated. In this study, the developmental neurotoxicity of OLA were evaluated zebrafish. Zebrafish embryos exposed to different concentrations (25–1,000 mg/L) from 6 120 hours post fertilization (hpf). exposure resulted many abnormal phenotypes zebrafish, including shortened body length, notochord degeneration, spinal curvature, brain...
The transmission risk of airborne diseases in public transportation systems is a concern. This paper proposes modified Wells-Riley model for analysis to capture the passenger flow characteristics, including spatial and temporal patterns, number boarding alighting passengers, infectors. used assess overall as function origin–destination flows, actual operations, factors such mask-wearing ventilation. integrated with microscopic simulation subway operations (SimMETRO). Using data from system,...
The denitrification catalyst without metal active component has excellent anti-poisoning performance and stability.
Many subway systems operating near capacity face challenges in meeting reliability and level of service targets. This paper examines the effectiveness various strategies to relieve congestion increase using a microscopic, agent-based, urban heavy rail simulation model. The Massachusetts Bay Transportation Authority’s (MBTA) Red Line serves as testbed for analysis. operates very close its capacity. Bottlenecks on possible mitigate them are discussed, including skip-stop, station...
A radical addition/cyclization cascade of o-cyanoarylacrylamides with magnesium nitrate hexahydrate is developed. This reaction exhibits good functional group tolerance and wide substrate scope, provides a highly efficient practical access to nitro-containing quinoline-2,4(1H,3H)-diones.
Diseases affecting cardiovascular system are ranked as a top most cause of morbidity and mortality. Herein, novel class sulphonamides-1,3,5-triazine conjugates have been synthesized tested for inhibitory activity against MMP-2 MMP-9. The results the study showed that these molecules efficiently inhibit MMP-9 than MMP-2, revealing compound 8e potent inhibitor (IC50 = 2.34 ± 0.56 nm). Due to involvement in many diseases, particularly myocardial ischaemia (MI), was further subjected...
Tourism development is one of the important channels to realize economic transformation closed coal mines. The suitability and modes tourism at mining sites resource-based cities are determined by their potentials. How measure potentials mine identify types has become an urgent research topic in field development. In this study, we established a model from three aspects: resources, conditions, urban environment; also completed empirical on China's resourcebased cities. results show that have...
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Non-invasive neuroimaging has revealed specific network-based resting-state dynamics in the human brain, yet underlying neurophysiological mechanism remains unclear. We employed intracranial electroencephalography to characterize local field potentials within default mode network (DMN), frontoparietal (FPN), and salience (SN) 42 participants. identified stronger within-network phase coherence at low frequencies (θ α band) DMN, high (γ FPN. Hidden Markov modeling indicated that DMN exhibited...
The application of the implementation strategy management cognitive practice monitoring system in economics and majors requires team teachers to have a high professional perspective fine practical operation ability. Only through in-depth analysis enterprise practices design truly relevant tools paths can any theoretical framework or model play its proper role achieve objectives talent training. This will require continuous testing improvement promote integration theory gradual formation...
The node-place model has been widely used to classify and evaluate transit stations, which sheds light on individual travel behaviors supports urban planning through effectively integrating land use transportation development. This article adapts this investigate whether how node, place, mobility would be associated with the transmission risks presences of local COVID-19 cases in a city. Similar studies its relevance COVID-19, according our knowledge, have not undertaken before. Moreover,...