A5043412893- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Ultrasound Imaging and Elastography
- Ultrasound and Hyperthermia Applications
- AI in cancer detection
- Global Cancer Incidence and Screening
- Photoacoustic and Ultrasonic Imaging
- Radiomics and Machine Learning in Medical Imaging
- Breast Implant and Reconstruction
- Digital Radiography and Breast Imaging
- Ultrasonics and Acoustic Wave Propagation
- HER2/EGFR in Cancer Research
- Cancer Genomics and Diagnostics
- Infrared Thermography in Medicine
- Reconstructive Surgery and Microvascular Techniques
- Medical Imaging Techniques and Applications
- Molecular Biology Techniques and Applications
- MRI in cancer diagnosis
- Bone fractures and treatments
- Bone health and osteoporosis research
- Oral and Maxillofacial Pathology
- BRCA gene mutations in cancer
- Health and Medical Studies
- Occupational and environmental lung diseases
- Thermoelastic and Magnetoelastic Phenomena
Klinikum Bielefeld
2021-2024
Francis Hospital
2010-2021
Leibniz University Hannover
2015
Medizinische Hochschule Hannover
2011-2014
St. Franziskus Hospital
2009-2014
Klinik für Frauenheilkunde
2007-2013
Olgahospital
2009-2010
Universitätsklinikum des Saarlandes
2007
Ziel: Die Hitachi Real-time Tissue Elastography (HI-RTE) erlaubt eine sonografische Abschätzung der Gewebeelastizität. Wir haben untersucht, ob durch die Sonoelastografie exaktere Vorhersage Dignität von Brustläsionen möglich ist. Material und Methoden: In einer multizentrischen Studie wurden 779 sonografisch untersucht anschließend histologisch gesichert. präsentieren Ergebnisse 3 Studienzentren (Berlin, Bielefeld, Homburg/Saar) in Hinblick auf Sensitivität (SE), Spezifität (SP) prädiktive...
Neoadjuvant systemic treatment (NST) elicits a pathologic complete response in 40%-70% of women with breast cancer. These patients may not need surgery as all local tumor has already been eradicated by NST. However, nonsurgical approaches, including imaging or vacuum-assisted biopsy (VAB), were able to accurately identify without residual cancer the axilla. We evaluated feasibility machine learning algorithm (intelligent VAB) exceptional responders NST.We trained, tested, and validated using...
Abstract: The idea of an automated whole breast ultrasound was developed three decades ago. We present our initial experiences with the latest technical advance in this technique, volume scanner (ABVS) ACUSON S2000 TM . Volume data sets were collected from 50 patients and a database containing 23 women no detectable lesions conventional (BI-RADS ® -US 1), 13 clearly benign 2), 14 known cancer 5) created. An independent examiner evaluated ABVS on separate workstation without any prior...
Triple-negative breast cancer (TNBC) is known to have unique molecular, clinical, and pathologic characteristics. The growth pattern of this may also affect its appearance on sonography. Our study evaluated the sonographic features TNBC according American College Radiology Breast Imaging Reporting Data System classification system compared these with those non-TNBC.Data from 315 consecutive cases were collected. images reevaluated by an examiner blinded patients' characteristics histologic...
Objective: We evaluated the ability of minimally invasive, image-guided vacuum-assisted biopsy (VAB) to reliably diagnose a pathologic complete response in breast (pCR-B). Summary Background Data: Neoadjuvant systemic treatment (NST) elicits up 80% women with cancer. In such cases, surgery, gold standard for confirming pCR-B, may be considered overtreatment. Methods: This multicenter, prospective trial enrolled 452 presenting initial stage 1-3 cancer all biological subtypes. Fifty-four...
Ziel: Das Ziel der Studie war es, die Messung Strain-Ratio von Brustläsionen innerhalb eines Elastogramms zu evaluieren, deren diagnostische Treffsicherheit bestimmen und Empfehlungen zur standardisierten Durchführung erarbeiten. Material Methoden: 117 98 Patientinnen wurden untersucht. Von allen Läsionen wurde eine B-Bild-Auswertung nach den BI-RADS-analogen Ultraschallkriterien DEGUM Elastogrammauswertung durch Ermittlung durchgeführt. Die Befunde abschließend histopathologisch...
To determine the general appearance of normal axillary lymph nodes (LNs) in real-time tissue sonoelastography and to explore method′s potential value prediction LN metastases. Axillary LNs healthy probands (n=165) metastatic breast cancer patients (n=15) were examined with palpation, B-mode ultrasound, Doppler (assessment elasticity cortex medulla). The distributions compared sensitivity (SE) specificity (SP) calculated. In an exploratory analysis, positive negative predictive values (PPV,...
Automated whole breast ultrasound scanners of the latest generation have reached a level comfortable application and high quality volume acquisition. Nevertheless, there is lack data concerning this technology. We investigated diagnostic performance inter-observer concordance Breast Volume Scanner (ABVS) ACUSON S2000™ questioned its implications in cancer diagnostics. collected 100 sets created database containing 52 scans with no detectable lesions conventional (BI-RADS®-US 1), 30 benign 2)...
Lesions of the breast that are classified BI-RADS®-US 3 by ultrasound probably benign and observation is recommended, although malignancy may occasionally occur. In our study, we focus exclusively on lesions hypothesize sonoelastography as an adjunct to conventional can identify a high-risk-group low-risk-group within these patients.A group 177 were additionally examined with real-time sonoelastography. Elastograms evaluated according Tsukuba Elasticity Score. Pretest posttest probability...
Acoustic radiation force impulse imaging (ARFI) with Virtual Touch™ tissue quantification (VTTQ) enables the determination of shear wave velocity (SWV) in meters per second (m/s). The aim our study was to describe mean SWV normal breast and various masses. We performed measurements ARFI VTTQ 145 masses (57 malignant, 88 benign) adjacent parenchyma adipose tissue. as well rate successful were analyzed. difference between statistically significant (3.05 versus 3.65 m/s) (P < 0.001). Focusing...
Abstract Objectives AI-based algorithms for medical image analysis showed comparable performance to human readers. However, in practice, diagnoses are made using multiple imaging modalities alongside other data sources. We determined the importance of this multi-modal information and compared diagnostic routine breast cancer diagnosis ultrasound interpretations by humans or algorithms. Methods Patients were recruited as part a multicenter trial (NCT02638935). The enrolled 1288 women...
Breast ultrasound has been established for many years as an important method in addition to mammography clarifying breast findings. The goal of the Best Practice Guidelines Part III DEGUM working group is provide colleagues senology with information regarding specific medical indications current criteria and assessment categories published part I additional optional sonographic diagnostic methods described II. value including follow-up, evaluation implants, workup dense tissue, during...
Breast ultrasound has been established for many years as an important method in addition to mammography clarifying breast findings. The goal of the Best Practice Guidelines Part III DEGUM working group is provide colleagues senology with information regarding specific medical indications current criteria and assessment categories published part I additional optional sonographic diagnostic methods described II. value including follow-up, evaluation implants, workup dense tissue, during...
The aim of this study was to evaluate the relation some ultrasound morphological parameters biological characteristics in breast carcinoma. Ultrasound data from 315 masses were collected. We analyzed features tumors according ACR BI-RADS®-US classification system stratified by hormone receptor status, HER2 histology grade, tumor type (ductal versus lobular), triple-negativity, density, size, lymph node involvement and patient's age. found a variety that varied between groups. Invasive...
In this prospective, multicenter trial we evaluated whether additional shear wave elastography (SWE) for patients with BI-RADS 3 or 4 lesions on breast ultrasound could further refine the assessment B-mode cancer diagnosis. We analyzed multicenter, international data from 1288 women rated by conventional 2 D as to 4c and undergoing 2D-SWE. After reclassification SWE proportion of undetected malignancies should be < %. All underwent histopathologic evaluation (reference standard)....
Alongside mammography, breast ultrasound is an important and well-established method in assessment of lesions. With the "Best Practice Guideline", DEGUM Breast Ultrasound (in German, "Mammasonografie") working group, intends to describe additional optional application modalities for diagnostic confirmation findings express recommendations this Part II, addition current dignity criteria categories published I, order facilitate differential diagnosis ambiguous lesions.The present Guideline"...
The purpose of this study was to determine the dependence breast tissue elasticity on menstrual cycle healthy volunteers by means real-time sonoelastography.Twenty-two (aged 18-33 years) were examined once weekly during two consecutive cycles using sonoelastography. Group 1 (n= 10) not taking hormonal medication; group 2 (n = 12) oral contraceptives.The parenchyma appeared softer than dermis and harder adipose tissue, varied over between groups. (no hormone intake) showed continuously...