A5087519851- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Radiopharmaceutical Chemistry and Applications
- Endometrial and Cervical Cancer Treatments
- Lung Cancer Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Medical Imaging and Pathology Studies
- MRI in cancer diagnosis
- Advanced X-ray and CT Imaging
- Cervical Cancer and HPV Research
- Artificial Intelligence in Healthcare and Education
- Ovarian cancer diagnosis and treatment
- Cardiac Imaging and Diagnostics
- Cancer Immunotherapy and Biomarkers
- Radiation Dose and Imaging
- Cancer Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Statistical Methods in Clinical Trials
- Treatment of Major Depression
- Prostate Cancer Treatment and Research
- Cerebrovascular and Carotid Artery Diseases
- Lymphatic System and Diseases
- Patient-Provider Communication in Healthcare
- Cancer Cells and Metastasis
University of Southern Denmark
2003-2025
Klinik und Poliklinik für Nuklearmedizin
2012-2025
Odense University Hospital
2015-2024
University of Copenhagen
2017
Rigshospitalet
2017
Copenhagen University Hospital
2017
To prospectively investigate the diagnostic accuracy of [(18)F]fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed (CT) with dual-time-point imaging, contrast-enhanced CT (ceCT), and bone scintigraphy (BS) in patients suspected breast cancer recurrence.One hundred women recurrence underwent 1-hour 3-hour FDG-PET/CT, ceCT, BS within approximately 10 days. The study was powered to estimate precision individual imaging tests. Images were visually interpreted using a four-point...
The gastrin-releasing peptide receptor (GRPR) is known to be overexpressed in breast cancer, making it a promising target for both imaging and therapy within theranostic framework. Various radioligands targeting GRPR have undergone investigation preclinical clinical studies related cancer. This systematic scoping review aimed assess the current evidence on GRPR-targeted diagnostic therapeutic applications methodology followed PRISMA-ScR protocol. literature search was conducted September...
Gender differences in antidepressant treatment response, side effects, dropout rates, and plasma concentrations were examined patients with major predominantly melancholic depression.The study included a subgroup of 292 inpatients (96 men, 196 women) from three Danish double-blind, randomized, controlled trials. All completed 5-week period fulfilled the DSM-III or DSM-III-R criteria for depression. Clomipramine (150 mg/day) was reference treatment, comparable treatments citalopram (40...
This study aimed to compare contrast-enhanced CT (CE-CT) and 18F-FDG PET/CT for response monitoring in metastatic breast cancer using the standardized evaluation criteria RECIST 1.1 PERCIST. The objective was examine whether progressive disease detected systematically earlier by one of modalities. Methods: Women with biopsy-verified were enrolled prospectively monitored combined CE-CT every 9-12 wk evaluate first-line treatment. scans used clinical decision-making without accessing scans. At...
Abstract This study aimed to compare CE-CT and 2-[ 18 F]FDG-PET/CT for response monitoring metastatic breast cancer (MBC). The primary objective was predict progression-free disease-specific survival responders vs. non-responders on F]FDG-PET/CT. secondary assess agreement between categorization the two modalities. Treatment in women with MBC monitored prospectively by simultaneous F]FDG-PET/CT, allowing participants serve as their own controls. standardized evaluation criteria solid tumors...
It is unclear if sentinel node (SLN) mapping can replace pelvic- (PLD) and paraaortic lymphadenectomy (PALD) for high-risk endometrial cancer (EC). A diagnostically safe surgical algorithm, taking failed cases into account, not defined. We aimed to investigate the diagnostic accuracy of SLN algorithms in women with exclusively EC.
This study aimed to determine the organ-specific accuracy of [18F]FDG-PET/CT in identifying immune-related adverse events (irAEs) patients with high-risk (stage III/IV) surgically resected melanoma treated an adjuvant immune checkpoint inhibitor (ICI) and incidence irAEs within first year after starting treatment. registry-based included individuals who had undergone surgical removal were undergoing ICI treatment (either nivolumab or pembrolizumab). The specifically enrolled both a baseline...
Despite increasing interest in patient involvement health care research, researchers may be uncertain about the benefits of involving patients design and conduction clinical studies. We aimed to evaluate impact on recruitment retention a study PET/CT women with advanced breast cancer. Further, we report our experience regarding researchers' attitudes towards as partners research process.Two representatives from Danish Breast Cancer Organization were invited team. These asked contribute...
We compared lesion-based sensitivity of dual-time-point FDG-PET/CT, bone scintigraphy (BS), and low-dose CT (LDCT) for detection various types metastases in patients with metastatic breast cancer. Prospectively, we included 18 recurrent cancer who underwent FDG-PET/CT LDCT BS within a median time interval three days. A total 488 lesions were detected on any the modalities categorized by into osteolytic, osteosclerotic, mixed morphologic, CT-negative lesions. Lesion-based was 98.2%...
Abstract Background [ 18 F]-fluorodeoxyglucose-positron emission tomography/computed tomography ([ F]FDG-PET/CT) has been implemented sporadically in hospital settings as the standard of care examination for recurrent breast cancer. We aimed to explore clinical impact implementing F]FDG-PET/CT patients with clinically suspected cancer and validate diagnostic accuracy. Methods Women distant were prospectively enrolled study between September 2017 August 2019. was performed, appearance...
<i>Background:</i> Studies of gender differences in the clinical presentation depression have provided divergent results. This study aimed at analyzing severity, symptomatology and distribution melancholia major depression. <i>Sampling Methods:</i> The comprised 930 in- out-patients (652 women, 278 men) from 6 randomized controlled trials. All patients fulfilled DSM-III or DSM-III-R criteria for 17-item Hamilton Depression Scale (HDS) was applied to all patients. A...