A5030866405- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Ovarian cancer diagnosis and treatment
- Prenatal Screening and Diagnostics
- Gynecological conditions and treatments
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- AI in cancer detection
- Ethics and Legal Issues in Pediatric Healthcare
- Patient-Provider Communication in Healthcare
- Family and Disability Support Research
- Urologic and reproductive health conditions
- Child and Adolescent Health
- Mechanical Circulatory Support Devices
- Medical and Health Sciences Research
- Workplace Health and Well-being
- Ethics in Clinical Research
- Maternal and Perinatal Health Interventions
- Estrogen and related hormone effects
- Lymphatic System and Diseases
- Emergency and Acute Care Studies
- Public Health and Social Inequalities
- Testicular diseases and treatments
- Sarcoma Diagnosis and Treatment
- Health and Medical Studies
Aarhus University Hospital
2010-2024
Aarhus University
2006-2014
Boehringer Ingelheim (Germany)
1969
Abstract Objectives To study associations between pregnant women's knowledge of prenatal screening and decisional conflict in deciding whether to participate first‐trimester for Down syndrome a setting required informed consent, personal wellbeing, worries pregnancy. Methods A population‐based cross‐sectional with 6427 women consecutively included before the time nuchal translucency scan. Participants were recruited from three Danish obstetric departments offering free charge. The results...
The SENTIREC-endo study aims to investigate risks and benefits of a national protocolled adoption sentinel lymph node (SLN) mapping in women with early-stage low-grade endometrial cancer (EC) low- (LR) intermediate-risk (IR) metastases.We performed multicenter prospective SLN-mapping LR IR EC from March 2017-February 2022. Postoperative complications were classified according Clavien-Dindo. Lymphedema was assessed as change score incidence swelling heaviness evaluated by validated...
It is unclear if sentinel node (SLN) mapping can replace pelvic- (PLD) and paraaortic lymphadenectomy (PALD) for high-risk endometrial cancer (EC). A diagnostically safe surgical algorithm, taking failed cases into account, not defined. We aimed to investigate the diagnostic accuracy of SLN algorithms in women with exclusively EC.
The primary aim of this study was to assess pregnant women's knowledge first-trimester combined Down syndrome screening in a setting required informed consent. As the secondary aim, we wanted identify relevant differences level among subgroups women, including those different ways about prenatal examinations.Data stem from population-based cross-sectional questionnaire 15 multiple-choice questions assessing aspects screening. Included were 6427 women three Danish obstetric departments...
Sentinel lymph node mapping is a minimally invasive surgical staging procedure that allows identification of macro- and micrometastases. The implementation sentinel to women with low-grade endometrial cancer detection metastases avoids the morbidity radical pelvic lymphadenectomy. extent myometrial invasion highly predictive but hard determine precisely preoperatively. exact rate in large group <50% low unknown. benefit detecting this should balance risk lymphedema. There limited knowledge...
Dynamic spectral imaging (DSI) colposcopy has previously been found to improve sensitivity of CIN2+ detection. The aim this study was compare the histological diagnosis colposcopic-directed biopsies (CDB) with that DSI-directed in women undergoing conization, using conization specimen as gold standard.Women referred for were included a prospective cohort at Randers Regional Hospital, Denmark, from January 2016 February 2019. All had four cervical punch taken. first biopsy taken area appeared...
ObjectiveTo identify women with high-risk endometrial cancers using expert and non-expert transvaginal ultrasonography (TVS) MRI.Study designMyometrial involvement was prospectively evaluated in patients atypical hyperplasia or cancer on ultrasound by non-experts at first visit (non-expert-TVS: n = 266) experts (expert-TVS: 188) second visit. MRI (n 175) performed when suspected non-expert-TVS. Preoperatively, defined as myometrial ≥50 %, preoperative unfavorable tumor histology (grade 3...
The aim of the study was to evaluate sensitivity dynamic spectral imaging (DSI) colposcopy compared with regular for women referred high-grade cervical cytology.In a prospective, nonrandomized, multicenter study, we included at hospital gynecology clinics cytology. Women were examined using either or DSI colposcope. In both groups, colposcopists located 1 area viewed as most suspicious. group, this done before viewing map. Subsequently, an chosen based on worst color map, and further...
Introduction: A rare case of dysgerminoma led to the prolonged and complex diagnostic journey a young woman. Methods: The process involved various imaging modalities, including ultrasound, FDG-PET/CT scan MRI, alongside laparoscopy. Additionally, methotrexate was administered based on provisional diagnosis manage patient’s condition. Results: Initial investigations suggested pregnancy unknown location due inconclusive ultrasound findings. Subsequent with initially appeared normal, but...
Abstract Background Colposcopy serves as a subjective examination of the cervix with low sensitivity to detect cervical intraepithelial dysplasia (CIN) grade 2 or worse (CIN2 +). Dynamic spectral imaging (DSI) colposcopy has been developed provide an objective element examinations and proven increase detecting CIN2 + . We aimed assess performance DSI color map compared it histological diagnoses biopsies in determining CIN present. Methods Women were included consecutive, prospective manner...
To evaluate efficiency of pattern diagnosis endometrial cancer obtained by use the risk (REC) score transvaginal sonography (TVS) and gelinfusion (GIS) in women with postmenopausal bleeding (PMB). Consecutive (950) PMB had TVS. In 457 TVS findings were indefinite GIS added. Women evaluated residencies supervised trained sonographers. Endometrial was scored according to (REC-score) system adding scores for: BMI (30+ = 1), thickness(ET) (10-14 ET (15+ vascularity, but not a single/double...
<h3>Background</h3> Improved work participation is an important goal in rehabilitation, and has socio-economic benefits. Despite this, there limited knowledge about how rehabilitation impacts ability across different diagnostic groups. <h3>Objectives</h3> To examine whether personal disease-related factors predict changes self-perceived one year after rehabilitation. <h3>Methods</h3> In a longitudinal multicenter cohort (RehabNytte) 17 centers Norway recruited more than 3700 patients with...
<h3>Introduction/Background</h3> Surgical staging of endometrial cancer (EC) serves to allocate women with lymph node metastases adjuvant treatment. Sentinel (SLN) mapping has shown high accuracy detect in EC low- or intermediate-risk (LR IR) metastases. The SENTIREC-endo study aims investigate risks and benefits a national protocolled adoption SLN LR IR EC, real-life clinical setting. <h3>Methodology</h3> Preceded by surgeon proficiency study, we performed multicenter prospective...
<h3>Introduction/Background</h3> Sentinel lymph node (SLN) mapping is suggested to be a safe surgical staging method for women with high-risk (grade 3 or non-endometrioid histology) endometrial cancer (EC). However, approximately 20% of do not have bilateral mapping, leaving need consensus on the choice algorithm in cases non-mapping. We aimed assess safety SLN algorithms EC. <h3>Methodology</h3> conducted national prospective study EC from March 2017- January 2023. A power calculation was...
<h3>Introduction</h3> Surgical staging of endometrial cancer (EC) serves to allocate women with lymph node metastases adjuvant treatment. Sentinel (SLN) mapping can accurately detect in EC low- or intermediate-risk (LR IR) metastases. We aim investigate risks and benefits a national protocolled adoption SLN LR IR EC, real-life clinical setting. <h3>Methods</h3> A multicenter prospective study SLN-mapping from March 2017-February 2022. Postoperative complications were classified according...
<h3>Introduction</h3> Sentinel lymph node (SLN) mapping is suggested to be a safe staging method for women with high-risk endometrial cancer (EC). However, approximately 20–45% of have failed mapping, leaving need consensus on the choice surgical algorithm in case non-mapping. We aimed assess safety SLN-mapping algorithms EC. <h3>Methods</h3> undertook national prospective diagnostic accuracy study EC from March 2017- January 2023. A power calculation was based negative predictive value...