A5030857518- Cancer, Lipids, and Metabolism
- Bladder and Urothelial Cancer Treatments
- Urinary Bladder and Prostate Research
- Artificial Intelligence in Healthcare and Education
- Cholesterol and Lipid Metabolism
- Phytoestrogen effects and research
- Sexual function and dysfunction studies
- Mobile Health and mHealth Applications
- Urinary Tract Infections Management
- Prostate Cancer Treatment and Research
- Inflammatory Biomarkers in Disease Prognosis
- Prostate Cancer Diagnosis and Treatment
- Hormonal and reproductive studies
- Genital Health and Disease
- Cancer Immunotherapy and Biomarkers
- Urologic and reproductive health conditions
- Digital Mental Health Interventions
- Extracellular vesicles in disease
- Pharmacological Effects and Assays
- Drug Transport and Resistance Mechanisms
- Radiation Dose and Imaging
- Telemedicine and Telehealth Implementation
- Radiology practices and education
- Sulfur Compounds in Biology
- Urinary and Genital Oncology Studies
University of Naples Federico II
2022-2024
Federico II University Hospital
2022-2024
Renal cell carcinoma (RCC) remains a formidable diagnostic challenge, especially in the context of small renal masses. The quest for non-invasive screening tools and biomarkers has steered research towards liquid biopsy, focusing on microRNAs (miRNAs), exosomes, circulating tumor cells (CTCs). MiRNAs, non-coding RNAs, exhibit notable dysregulation RCC, offering promising avenues diagnosis prognosis. Studies underscore their potential across various biofluids, including plasma, serum, urine,...
Lipid alterations may serve as potential tumour biomarkers. The ratio of triglycerides to HDL cholesterol (TG/HDL ratio) is associated with various cancers. Pseudocholinesterase (PChE) activity, involved in TG hydrolysis, plays an important role the metabolism lipoprotein. There scarce data assessing reliability both TG/HDL and PChE levels correctly classifying patients suffering from bladder cancer.Three hundred ninety-six undergoing cystoscopy or transurethral resection (TURB), broken into...
Bacterial prostatitis (BP) is a common prostatic infection characterized by bimodal distribution in young and older men, with prevalence between 5-10% among all cases of high impact on quality life. Although the management bacterial involves use appropriate spectrum antibiotics, which represent first choice treatment, multimodal approach encompassing antibiotics nutraceutical products order to improve efficacy chosen antimicrobial regimen often required.To evaluate Flogofilm® association...
Background and objective: Fibrinogen albumin are two proteins widely used, singularly in combination, cancer patients as biomarkers of nutritional status, inflammation disease prognosis. The aim our study was to investigate the preoperative fibrinogen-to-albumin ratio (FAR) a predictor malignancy well advanced grade with bladder cancer. Materials Methods: A retrospective analysis who underwent TURBT at institution between 2017 2021 conducted. FAR obtained from venous blood samples performed...
Benign prostatic hyperplasia (BPH) is a common urological condition affecting aging men worldwide. Among the treatment options available for BPH, transurethral resection of prostate (TURP) gold-standard invasive intervention. To reduce TURP-related non-negligible morbidity, loss-of-ejaculation rate, hospitalization, blood loss and catheterization time several laser techniques have been developed, such as Thulium Laser Enucleation Prostate (ThuLEP). investigate efficacy outcomes ThuLEP option...
There is a strong clinical need to fill the gap of identifying clinically significant prostate cancer (csPCa) in men with prostate-specific antigen (PSA) gray zone values. Promising, but not definitive results have been obtained using PSA derivatives such as health index (PHI) and PHI density (PHID) percentage (-2)proPSA/free (%p2PSA/fPSA). Thus, this study aimed compare diagnostic value PHI, PHID, %proPSA/fPSA, (-2)proPSA/freePSA (-2pPSA/fPSAD) for csPCa patients within 2-10 ng/mL.
To evaluate the potential advantages of software-assisted structured reporting for radiology residents approaching multiparametric prostate MRI (mpMRI).
Peyronie's disease affects up to 9% of men and is often accompanied by pain and/or erectile dysfunction. It characterized an inflammatory process that the grassroots subsequent fibrosis stage. There unmet need evaluate its onset progression. Among newly proposed biomarkers inflammation, authors developed a novel systemic immune-inflammation index (SII) based on lymphocyte, neutrophil, platelet counts. Similarly, recent study reported neutrophil-to-eosinophil ratio (NER) represents...