Sen Guo

ORCID: 0000-0003-2740-0744
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Research Areas
  • Cutaneous Melanoma Detection and Management
  • Melanoma and MAPK Pathways
  • Protein Degradation and Inhibitors
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Cerebrospinal fluid and hydrocephalus
  • Phytochemicals and Antioxidant Activities
  • Natural product bioactivities and synthesis
  • Viral Infectious Diseases and Gene Expression in Insects
  • Cancer, Lipids, and Metabolism
  • Spinal Dysraphism and Malformations
  • Nanoplatforms for cancer theranostics
  • MicroRNA in disease regulation
  • Energy, Environment, Agriculture Analysis
  • Natural Antidiabetic Agents Studies
  • Phytochemistry and Biological Activities
  • Advanced Neuroimaging Techniques and Applications
  • Pancreatic and Hepatic Oncology Research
  • Ferroptosis and cancer prognosis
  • Atherosclerosis and Cardiovascular Diseases
  • Chalcogenide Semiconductor Thin Films
  • Pregnancy-related medical research
  • 2D Materials and Applications
  • Environmental and Social Impact Assessments
  • Traditional Chinese Medicine Analysis

First Affiliated Hospital of Zhengzhou University
2025

North China Electric Power University
2021-2025

Air Force Medical University
2025

Xijing Hospital
2025

Juntendo University
2023-2024

Northwest University
2022-2024

Qilu Hospital of Shandong University
2017-2022

Shaanxi Normal University
2021

Guangdong University of Technology
2021

Chengde Medical University
2020

Twenty glycoside derivatives and nine flavonoids from the leaves of Pueraria (P. thomsonii) were isolated by column chromatography characterized nuclear magnetic resonance spectroscopy (NMR) high performance liquid (HPLC). The contents twenty glycosides extract P. thomsonii leaf (PL) 173.3 mg g-1 134.7 g-1, respectively. Two with highest content robinin (49.28 g-1) puerarin (42.87 g-1). Six flavonoids, i.e. puerarin, robinin, rutin, quercetin, quercitrin, kaempferol showed more inhibitory...

10.1039/d1fo04170c article EN Food & Function 2022-01-01

Low-carbon development (LCD) in China has become the critical measure to achieve sustainable and handle climate change. This investigation evaluates 30 provincial regions’ LCD quality from dimensions of low-carbon (LC) economy, resources utilization, LC environment, society. According integrated weights combined subjective identified through best–worst method (BWM) objective attained anti-entropy weight (AEW) method, top five sub-criteria 2021 were coal consumption relative total primary...

10.3390/su17062425 article EN Sustainability 2025-03-10

Hepatocellular carcinoma (HCC) is a well-described complication of Budd-Chiari syndrome (BCS). However, the risk factors BCS in developing HCC and clinical characteristics imaging features BCS-associated still to be determined.Data from 113 consecutive patients with primary Qilu hospital were retrospectively studied. The 12 associated also analyzed. Chi-square analysis was performed analyze differences characteristics. treatment regime CT illustrated.113 admitted our between January 2009...

10.3389/fonc.2022.1075685 article EN cc-by Frontiers in Oncology 2022-12-08

Todani classification is extensively used to guide the surgical strategy of choledochal cysts, but no systematic investigations on distal management intrapancreatic cysts have been conducted. This study reports and in adults based relation between cyst pancreatic duct. Patients with who underwent operation, including management, our department from January 2009 December 2014 were retrospectively reviewed. presenting symptoms, coexisting diseases, treatment, perioperative complications,...

10.1097/md.0000000000006350 article EN cc-by-nc Medicine 2017-03-01

Abstract Objective This study aimed to explore alterations in diffusion tensor image analysis along the perivascular space (DTI-ALPS) method and choroid plexus volume (CPV), which could be biomarkers of glymphatic system older adults with poor sleep quality (PSQ). Methods Fifty-two Japanese Pittsburgh Sleep Quality Index (PSQI) scores > 5 (22 men 30 women; mean age ± SD = 73.10 5.67 years) 52 healthy controls (HCs; PSQI score ≤ 5) were included. Diffusion-weighted imaging (DWI) 3D...

10.21203/rs.3.rs-4244404/v2 preprint EN cc-by Research Square (Research Square) 2024-04-11

Motivation: Our previous study revealed abnormalities in aquaporin 4, which works at the cerebrospinal–interstitial fluid exchange postmortem brains of patients with bipolar disorder (BP). However, glymphatic system (GS) alterations BP are still unclear. Goal(s): This aims to assess GS function patients. Approach: We used diffusion tensor image analysis along perivascular space (DTI–ALPS) method subjects and healthy controls (HCs). Results: The ALPS index was...

10.58530/2024/2637 article EN Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition 2024-11-26

Motivation: Although multi-site DWI with large sample size has high statistical power and is sensitive to the subtle microstructural tissue changes, different models or protocols-induced measurement biases affect reliability reproducibility of study. Therefore, harmonization necessary improve this issue. Goal(s): The goal our study evaluate effectiveness ComBat in mitigating FBA measures. Approach: Our utilized a traveling-subject dataset, while various measures were calculated subsequently...

10.58530/2024/3002 article EN Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition 2024-11-26

ABSTRACT This study included 52 Japanese older adults with Pittsburgh Sleep Quality Index (PSQI) scores > 5 and healthy controls (HCs) PSQI score ≤ 5. Diffusion‐weighted imaging (DWI) 3D T1‐weighted were acquired using 3T magnetic resonance imaging. The diffusion tensor image analysis along the perivascular space (DTI‐ALPS) index was calculated preprocessed DWI. choroid plexus volume (CPV) FreeSurfer 6.0. mean ALPS CPV compared between poor sleep quality (PSQ) HCs a general linear model,...

10.1002/jnr.70005 article EN Journal of Neuroscience Research 2024-11-29

Separate electron and hole dynamic processes during the formation process of lowest excitons at <italic>K</italic>-valley in few-layer WS<sub>2</sub>.

10.1039/d1cp00250c article EN Physical Chemistry Chemical Physics 2021-01-01

Previous studies have validated that participants can distinguish different origins of objects' shape features, teasing apart features caused by transformation (causal history) from those the original shape. Considering bite as a example, two experiments were designed to investigate effect causal history on allocation visual attention. Participants presented with regular and familiar complete or bitten shapes in Experiment 1 unfamiliar irregular 2 over range stimulus onset asynchronies...

10.1167/jov.21.11.17 article EN cc-by-nc-nd Journal of Vision 2021-10-25

With the internationalization of RMB and openness China’s capital account, amount foreign institutions investing in China has increased significantly. Based on daily data from January 2007 to September 2021, this study investigated factors that affect carry-trade return for sustainability. By comparing results carry before after foreign-exchange reform 11 August 2015, found become more traceable exchange-rate reform. Meanwhile, model fitting degree explaining was higher, there were fewer...

10.3390/su132413533 article EN Sustainability 2021-12-07

Fraxinus mandshurica is widely distributed around the world, which has significant economic value and pharmacological effects. However, its roots are often overlooked during processing use. In this study, preliminary identification of chemical components in F. was carried out using UPLC-ESI-Q-TOF-MS technique, a total 37 characteristic were identified, including 13 secoiridoids, 7 lignans, 6 coumarins, 4 flavonoids, phenylethanols, 1 terpenoids 2 other compounds. Meanwhile, to evaluate major...

10.2139/ssrn.4374039 article EN 2023-01-01
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