A5008583745- Circadian rhythm and melatonin
- Sleep and related disorders
- Genetic Associations and Epidemiology
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Impact of Light on Environment and Health
- Alzheimer's disease research and treatments
- Mental Health Research Topics
- Diet and metabolism studies
- Physical Activity and Health
- Diet, Metabolism, and Disease
- Cardiovascular Health and Risk Factors
- Pancreatic and Hepatic Oncology Research
- Adipokines, Inflammation, and Metabolic Diseases
- Heart Rate Variability and Autonomic Control
- Epigenetics and DNA Methylation
- Health and Lifestyle Studies
- Dementia and Cognitive Impairment Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Consumer Attitudes and Food Labeling
- Drug Transport and Resistance Mechanisms
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Food composition and properties
- Growth Hormone and Insulin-like Growth Factors
- Systemic Lupus Erythematosus Research
The University of Texas Health Science Center at Houston
2022-2024
University of Hong Kong
2017-2023
Faculty of Public Health
2019
Systemic inflammation has been suggested to be associated with Alzheimer's-disease progression, although whether it is a cause or downstream effect still controversial. This study aims assess the of systemic inflammatory regulators on Alzheimer's disease within bidirectional Mendelian-randomization design.Genetic associations were obtained from largest and most up-to-date genome-wide association (GWAS) (cases proxy cases: 71 880; controls: 383 378) two recent GWASs human proteome cytokines....
OBJECTIVE The alignment between environmental stimuli (e.g., dark, light) and behavior cycles rest, activity) is an essential feature of the circadian timing system, a key contributor to metabolic health. However, no previous studies have investigated light-activity in relation glycemic control human populations. RESEARCH DESIGN AND METHODS analysis included ∼7,000 adults (aged 20–80 years) from National Health Nutrition Examination Survey (NHANES) (2011–2014) with actigraphy-measured,...
Food reformulation has been suggested to be one of the strategies reduce population added sugar (AS) intake. This study aims investigate untested assumption that a reduction in AS through will result intakes and energy. Plausible dietary data from 4,140 respondents an Australian national nutrition survey were used. Dietary modelling was performed at reductions 10%, 15%, 25% using four strategies: simple removal or replacement with non-nutritive sweeteners (NNS), NNS either: polyols, 50%...
Abstract Proper alignment of activity-rest and light–dark patterns allows for healthy bodily functions to occur at optimal times the day. Disruptions this may cause poor sleep as well physical, mental, cognitive problems. The purpose cross-sectional study was determine if poorer circadian associated with decreased functioning among older (> 60 years) participants in National Health Nutrition Examination Survey. We utilized actigraphy-based rest-activity dark-light measurements calculate...
People with disrupted circadian rhythms, such as shift workers, have shown a higher risk of hypertension. However, it is unclear whether more subtle differences in diurnal rest-activity rhythms the population are associated Clarifying association between rhythm, modifiable behavioural factor, and hypertension could provide insight into preventing possibly cardiovascular diseases. In this study, we investigated rhythm characteristics large representative sample United States adults....
Immune system functioning is relevant to vulnerability coronavirus disease (COVID-19). Cytokines are important immunity. To further elucidate the role of immune in COVID-19, we used Mendelian randomization (MR) assess comprehensively and bi-directionally cytokines COVID-19.We assessed primarily whether genetically different levels 41 affected risk any COVID-19 (laboratory confirmed, physician confirmed or self-reported, 36,590 cases, 1,668,938 controls), conversely if genetic liability these...
Abstract Background Suboptimal rest-activity patterns in adolescence are associated with worse health outcomes adulthood. Understanding sociodemographic factors rhythms may help identify subgroups who benefit from interventions. This study aimed to investigate the association of rhythm demographic and socioeconomic characteristics adolescents. Methods Using cross-sectional data nationally representative National Health Nutrition Examination Survey (NHANES) 2011–2014 adolescents (N = 1814),...
Liver functions are regulated by the circadian rhythm; however, whether a weakened rhythm is associated with impaired liver function unclear. This study aims to investigate association of characteristics rest–activity rhythms abnormal levels biomarkers function. Data were obtained from National Health and Nutrition Examination Survey 2011–2014. Seven parameters derived 24 h actigraphy data using extended cosine model non-parametric methods. Multiple logistic regression multiple linear models...
This study aims to examine whether there were changes between 1995–2012 in the dietary glycaemic index (dGI) and load (dGL) Australian children (<16 years) according three national surveys 1995 (1995NS), 2007 (2007NS), 2011–2012 (2012NS). Glycaemic (GI) values of foods assigned using published methodology. Plausible 24-h recall data from 1995NS, 2007NS 2012NS (weighted n = 2475, 4373 1691 respectively) compared for differences dGI dGL, contribution dGL different one-way ANOVA with...
Abstract Introduction Diet, sleep, and rest-activity rhythms (RAR) influence cardiometabolic health but the relationship among these behaviors is less clear. Evidence of associations between sleep diet have focused on self-reported duration quality, rarely investigated timing, regularity, RAR metrics. This study assessed cross-sectional regularity timing with overall quality. Methods Multi-ethnic Study Atherosclerosis (MESA) participants who completed validated food frequency questionnaires...
<p dir="ltr">Objective</p><p dir="ltr">The alignment between environmental stimuli (e.g., light) and behavior cycles rest-activity) is an essential feature of the circadian timing system, a key contributor to metabolic health. However, no previous studies have investigated light-activity in relation glycemic control human populations.</p><p dir="ltr">Research Design Methods</p><p analysis included ~7000 adults (age 20-80) from National Health Nutrition...
<p dir="ltr">Objective</p><p dir="ltr">The alignment between environmental stimuli (e.g., light) and behavior cycles rest-activity) is an essential feature of the circadian timing system, a key contributor to metabolic health. However, no previous studies have investigated light-activity in relation glycemic control human populations.</p><p dir="ltr">Research Design Methods</p><p analysis included ~7000 adults (age 20-80) from National Health Nutrition...