A5015446291- Endoplasmic Reticulum Stress and Disease
- RNA regulation and disease
- Orthodontics and Dentofacial Orthopedics
- RNA and protein synthesis mechanisms
- Oral Health Pathology and Treatment
- Cleft Lip and Palate Research
- Salivary Gland Tumors Diagnosis and Treatment
- Craniofacial Disorders and Treatments
- Protein Structure and Dynamics
- Salivary Gland Disorders and Functions
- Pancreatic function and diabetes
- CRISPR and Genetic Engineering
- Racial and Ethnic Identity Research
- Fungal and yeast genetics research
- Autophagy in Disease and Therapy
- Yeasts and Rust Fungi Studies
- Glycosylation and Glycoproteins Research
- Fermentation and Sensory Analysis
Universidade Federal do Rio de Janeiro
2022
University of California, San Francisco
2013-2019
Howard Hughes Medical Institute
2013-2019
Brown University
2014
University of California, Berkeley
2013
QB3
2013
The unfolded protein response (UPR) detects and restores deficits in the endoplasmic reticulum (ER) folding capacity. Ceapins specifically inhibit UPR sensor ATF6α, an ER-tethered transcription factor, by retaining it at ER through unknown mechanism. Our genome-wide CRISPR interference (CRISPRi) screen reveals that function is completely dependent on ABCD3 peroxisomal transporter. Proteomics studies establish physically associates with ER-resident ATF6α cells vitro a Ceapin-dependent manner....
The aim of this retrospective cross-sectional study was to verify the association between salivary flow rates (SFR) and histopathologic aspects labial glands (LSG) in patients with rheumatoid arthritis (RA). Patients presenting rheumatologic diseases referred for oral evaluation were included if they had RA SFR measured LSG biopsy performed. excluded systemic conditions that affect or being treated hyposalivation. Cases without enough material analysis also excluded. Data collected through...
Introdução: em pacientes que apresentam mordida cruzada posterior e/ou atresia maxilar, a expansão rápida da maxila (ERM) é, geralmente, o tratamento ortodôntico de escolha, seja crianças, adolescentes ou adultos jovens. Esse tipo terapia requer confecção aparelho ortodôntico/ortopédico, muitas vezes dentomucossuportado e com ativações diárias. Objetivo: presente trabalho teve como objetivo descrever quatro casos clínicos apresentaram complicações decorrentes do procedimento ERM, formação...