Abstract Background Medical literature searches provide critical information for clinicians. However, the best strategy identifying relevant high‐quality is unknown. Objectives We compared search results using P ub M ed and G oogle S cholar on four clinical questions analysed these with respect to article relevance quality. Methods Abstracts from first 20 citations each were classified into three categories. used weighted kappa statistic analyse reviewer agreement nonparametric rank tests...

Radon is an established human lung carcinogen naturally released as odorless, colorless gas from soil and rocks. It a major environmental source of ionizing radiation can cause oxidative damage to DNA, increasing the risk cancer. Although association between radon cancer well established, other cancers not. Based on reported studies, there no consistent evidence indicating non-solid solid cancers, but limited literature, heterogenous study design, confounding variables preclude definitive...

Cardiopulmonary exercise testing (CPET) provides important information for the assessment and management of patients with heart failure. This measures respiratory cardiac responses to allows measurement oxygen uptake (V˙O2) max relationship between minute ventilation (V˙E) carbon dioxide excretion (V˙CO2). These two parameters help classify into categories that predict prognosis, a V˙O2 < 14 mL/kg/min V˙E/V˙CO2 slope >35 have poor prognosis. has been used in drug trials determine...

Virus replication and interstitial pneumonia were studied in BALB/c mice inoculated intranasally with murine cytomegalovirus (MCMV). In normal MCMV replicated lung tissue but did not produce any consistent histologic abnormalities through day 21. The addition of a single dose cyclophosphamide (0.20 mg/g) 24 hr after virus inoculation resulted slight increase titers on 10. No noted before However, 22 32 virus-infected treated only two 26 simultaneously mock-infected, cyclophosphamide-treated...

COVID-19 vaccination related adverse events is an evolving field. Here we present a case of acute myocardial injury that developed as result immune response following the second dose (Moderna) in 67-year-old man who presented congestive heart failure. His clinical course improved over 3 days. Review Vaccine Adverse Events Reporting System (VAERS) Centers for Disease Control and Prevention websites identified 37 vaccine recipients myocarditis event vaccination. With mass expansion...

The 2020 COVID-19 pandemic has produced an unprecedented amount of scientific research, with over 100,000 articles on the SARS-COV2 virus or associated published within first year. To effectively disseminate such a large volume some academic journal publishers altered their review criteria, and many were made available before undergoing traditional process. However, this rapid influx information, multiple have been retracted withdrawn. Some researchers expressed concern that these...

According to the World Health Organization, approximately 20 million people worldwide are infected annually with hepatitis E virus (HEV). There 4 main genotypes of HEV. Genotype 1 and genotype 2 common in developing countries transmitted by contaminated water from a fecal-oral route. 3 developed can lead occasional transmission humans undercooked meat. Hepatitis HEV3 fulminant hepatitis, chronic cirrhosis immunocompromised patients. The majority patients HEV infection asymptomatic usually...

Hepatitis B virus (HBV) infections affect approximately 296 million people around the world, and prevalence of any past or present HBV infection during years 2015–2018 was as high 4.3%. Acute often presents with nonspecific symptoms is usually self-limited, but 5% patients can have persistent leading to chronic risk turning into significantly higher in babies vertical transmission (95%). Patients are asymptomatic, 15 40% carriers develop cirrhosis and/or hepatocellular carcinoma. In addition...