A5051257281- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Tracheal and airway disorders
- Neonatal Respiratory Health Research
- Asthma and respiratory diseases
- Pediatric health and respiratory diseases
- Diet and metabolism studies
- Sleep and Wakefulness Research
- Cleft Lip and Palate Research
- Infant Health and Development
- Gastrointestinal motility and disorders
- Respiratory and Cough-Related Research
- Respiratory viral infections research
- Infant Development and Preterm Care
- Cardiovascular and Diving-Related Complications
- Oral and Craniofacial Lesions
- Congenital Diaphragmatic Hernia Studies
- Gut microbiota and health
- Congenital Heart Disease Studies
- Cardiovascular Syncope and Autonomic Disorders
- Omental and Epiploic Conditions
- Migraine and Headache Studies
- Retinal Imaging and Analysis
- Appendicitis Diagnosis and Management
- Colorectal Cancer Screening and Detection
Azienda Ospedaliera Sant'Andrea
2016-2025
Sapienza University of Rome
2016-2025
CTO Andrea Alesini
2017-2023
The Sense Innovation and Research Center
2015
to evaluate the efficacy and safety of co-micronized palmitoylethanolamide (PEA)/polydatin (PD) in treatment abdominal pain symptoms pediatric patients with Irritable Bowel Syndrome (IBS). The study was a multicenter trial conducted at three Italian gastroenterology centers, employing double-blind, placebo-controlled, parallel-arm design. Participants, aged 10 17 years, met Rome IV criteria for IBS. They were randomly allocated receive either PEA/PD or placebo, administered times daily 1:1...
IMPORTANCE Although polysomnographic (PSG) testing is the gold standard for diagnosis of obstructive sleep apnea syndrome (OSAS) in children, number pediatric laboratories limited.Developing new screening methods identifying OSAS may reduce need PSG testing.OBJECTIVE To evaluate combined use clinical record (SCR) and nocturnal oximetry predicting results children with clinically suspected OSAS.DESIGN, SETTING, AND PARTICIPANTS Prospective study over 10 months.A cohort 268 consecutive (mean...
Bronchiolitis is the leading cause of hospitalization in infants under 12 months. Our aims were to analyze epidemiological characteristics with bronchiolitis over 10 consecutive seasons and evaluate whether there are any clinical differences between hospitalized for during epidemic peak months non-peak We enrolled 723 previously healthy term at Paediatric Emergency Department, "Sapienza" University Rome period 2004-2014. Fourteen respiratory viruses detected from nasopharyngeal aspirates by...
In children, the effect of common phenotype obstructive sleep apnea (OSA) on architecture is not adequately documented. The aim this study was to evaluate in a pediatric population with OSA.The prospective cross-sectional included 116 children age range 3 8 years suspected OSA and 51 healthy children. All underwent standard overnight in-laboratory video polysomnography. Patients apnea-hypopnea index ≥ 1, adenotonsillar hypertrophy, long face, narrow palate or minor malocclusions, no obesity...
Background: The gut microbiota plays a pivotal role in gastrointestinal inflammation and immune response since changes may result abnormal neurotransmitter expression, inducing sensory–motor function leading to symptom onset irritable bowel syndrome (IBS) patients. Bifidobacterium adolescentis species has documented immunomodulatory effect through its ability produce γ-aminobutyric acid (GABA), the primary inhibitory mammalian central nervous system, which is reduced IBS Aim Methods: This...
Background: A brief resolved unexplained event (BRUE) is a brief, sudden episode occurring in infants younger than 1 year of age, characterized by some combination absent, decreased, or irregular breathing, an altered level responsiveness, color change, and change muscle tone. Although inappropriate feeding has been suggested as playing role the occurrence BRUEs, only anecdotal reports have described. The main objective our study was to objectively evaluate whether overfeeding may represent...
Obstructive sleep apnea syndrome (OSAS) is a sleep-related breathing disorder that very common in pediatric patients. In the literature, there are few studies concerning association between OSAS and class III malocclusion children. The use of rapid maxillary expander (RME) with Delaire mask treatment protocol for malocclusion. aim this work was to evaluate cephalometric variations upper airway dimensions OSA-related clinical conditions after orthodontic an RME mask, as recorded patients who...