Angela Mauro
A5057191809- Kawasaki Disease and Coronary Complications
- Autoimmune and Inflammatory Disorders Research
- Inflammasome and immune disorders
- Ocular Diseases and Behçet’s Syndrome
- Systemic Lupus Erythematosus Research
- Vasculitis and related conditions
- Streptococcal Infections and Treatments
- Coronary Artery Anomalies
- Eosinophilic Esophagitis
- Retinal and Optic Conditions
- Diabetes and associated disorders
- Adolescent and Pediatric Healthcare
- Celiac Disease Research and Management
- COVID-19 Clinical Research Studies
- Immunodeficiency and Autoimmune Disorders
- Intestinal Malrotation and Obstruction Disorders
- Rheumatoid Arthritis Research and Therapies
- Gastrointestinal disorders and treatments
- Otitis Media and Relapsing Polychondritis
- Child and Adolescent Health
- Hernia repair and management
- Neonatal Health and Biochemistry
- Emergency and Acute Care Studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Eosinophilic Disorders and Syndromes
ASST Fatebenefratelli Sacco
2022-2025
Fatebenefratelli Hospital
2023-2024
Santobono Children's Hospital
2020-2023
Mylan (Switzerland)
2023
Meyer Children's Hospital
2015-2018
University of Florence
2017-2018
University of Campania "Luigi Vanvitelli"
2010-2017
University of Naples Federico II
2010-2017
Ospedale San Giacomo Apostolo
2017
to evaluate the efficacy and safety of co-micronized palmitoylethanolamide (PEA)/polydatin (PD) in treatment abdominal pain symptoms pediatric patients with Irritable Bowel Syndrome (IBS). The study was a multicenter trial conducted at three Italian gastroenterology centers, employing double-blind, placebo-controlled, parallel-arm design. Participants, aged 10 17 years, met Rome IV criteria for IBS. They were randomly allocated receive either PEA/PD or placebo, administered times daily 1:1...
Behçet's disease is a rare multi-systemic inflammatory with unknown etiology which involves principally oral and genital mucosa, skin eyes. Average age at onset of the about 25-30 years, but it may be diagnosed before 16. It not very in Italy, even though there are limited data concerning epidemiology. Aim this study to describe baseline an Italian cohort patients as having BD or probable BD. We described first national epidemiological on children coming from 16 Pediatric Rheumatologic...
Objectives: The aim of this study was to assess the impact COVID-19 pandemic and population lockdown on pediatric ED consultations. Methods: A cross-sectional emergency department consultations before during current (March -May 2019 vs March - May 2020) performed in two hospitals Campania region (Southern Italy), i.e. Salerno University Hospital (Salerno) Pediatric Regional Referral Emergency Hub "AORN Santobono-Pausillipon" (Naples). Results: 29,368 consecutive patients (13,430 females;...
Still's disease is more frequently observed in the paediatric context, but a delayed onset not exceptional both adulthood and elderly. However, whether paediatric-onset, adult-onset elderly-onset represent expressions of same continuum or different clinical entities still matter controversy. The aim this study to search for any differences demographic, features response treatment between pediatric-onset, disease.Subjects included were drawn from International AutoInflammatory Disease...
Abstract Objective The main aim of this study was to define the best treatment option for multisystem inflammatory syndrome in children (MIS-C) and analyse role anakinra. Methods This is a multicentre retrospective cohort study. Patients were treated according attending physician’s decision. patients divided into four groups on basis first at time admittance: (i) IVIG, (ii) IVIG methylprednisolone (≤2 mg/kg/day), (iii) with high-dose (>2 mg/kg/day) (iv) anakinra or without and/or...
Scientific evidence of the effectiveness tumor necrosis factor inhibitor adalimumab (ADA) in pediatric patients with non-infectious non-anterior uveitis is still limited. The aim this study to investigate therapeutic role ADA a cohort uveitis. This an international multicenter analyzing real-life data referred treated for intermediate uveitis/pars planitis, posterior and panuveitis. Data were drawn from AutoInflammatory Disease Alliance (AIDA) registry Twenty-one (36 affected eyes) enrolled,...
To evaluate the potential role of Streptococcus salivarius K12 (SSK12) in controlling febrile flares patients with Periodic Fever, Aphthous stomatitis, Pharyngitis, and cervical Adenitis (PFAPA) syndrome. Further aims were to assess impact SSK12 on (i) flare duration, (ii) variation degree highest body temperature during flares, (iii) steroid-sparing effect, (iv) change PFAPA accompanying symptoms before after introduction.The medical charts from 85 pediatric syndrome (49 males 36 females)...
Involvement of the temporomandibular joint (TMJ) in patients with juvenile idiopathic arthritis (JIA) has been increasingly reported, affecting up to 87% cases. This involvement generally occurs after diagnosis JIA established; however, authors' cases, as a few others documented literature, presented isolated TMJ sole involvement. The authors performed narrative literature review on and reported 2 cases that initial manifestation JIA. Although may be rare, it can lead severe complications,...
This study aims to characterize ocular manifestations of juvenile Behçet's disease (jBD).
The study objective was to compare the effectiveness of adalimumab (ADA) in monotherapy and combination with methotrexate (MTX) for paediatric noninfectious uveitis (NIU). Registry-based observational study. Children receiving ADA active were divided into group (group 1) plus MTX 2). Eighty four children enrolled (146 eyes): 22 1 (26.2%) 62 2 (73.8%). complete 48 (57.1%), partial 23 (27.4%) absent 4 (5.3%), without any differences across groups (p = 0.89). Fewer relapses per 100 PY occurred...
Kawasaki disease (KD) is a systemic vasculitis with an acute and self-limited course. The incidence of KD differs widely among ethnic groups higher in the Asian population. In Italy, no recent data are available. Our purpose to define epidemiology years 2008–2013 children aged < 14 Italian regions Tuscany Emilia Romagna through administrative data. We studied 0–14 old resident using hospital ICD-9 discharge codes thorough cleaning for duplicates. distribution patients across ages was similar...
Since many biological drug patents have expired, biosimilar agents (BIOs) been developed; however, there are still some reservations in their use, especially childhood. The aim of the current study is to evaluate efficacy and safety tumor necrosis factor (TNF) inhibitors BIOs as treatment for pediatric non-infectious uveitis (NIU).
Background: Multisystem inflammatory syndrome in children (MIS-C) is a disease temporally related to severe acute respiratory coronavirus 2 (SARS-CoV-2) and it characterized by fever, conjunctival injections, rash, gastrointestinal symptoms, cardiovascular complications. We evaluated the clinical presentation, laboratory findings, imaging features, therapeutic interventions, hospital course of monocentric cohort, we analyzed these findings according two age groups. Methods: Patients with...