Marilia Ambiel Dagostin
A5040038857- Autoimmune and Inflammatory Disorders Research
- Vasculitis and related conditions
- Otitis Media and Relapsing Polychondritis
- Inflammasome and immune disorders
- Adolescent and Pediatric Healthcare
- Kawasaki Disease and Coronary Complications
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Bone Metabolism and Diseases
- Family and Disability Support Research
- Acute Lymphoblastic Leukemia research
- Nosocomial Infections in ICU
- Oral Health Pathology and Treatment
- Immune Cell Function and Interaction
- Sinusitis and nasal conditions
- Drug-Induced Adverse Reactions
- Biomarkers in Disease Mechanisms
- Clostridium difficile and Clostridium perfringens research
- Inflammatory Myopathies and Dermatomyositis
- Retinal Diseases and Treatments
- interferon and immune responses
- Skin Diseases and Diabetes
- Cell Adhesion Molecules Research
- Heparin-Induced Thrombocytopenia and Thrombosis
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2021-2024
Universidade de São Paulo
2018-2024
Hospital Universitário da Universidade de São Paulo
2023
Still's disease is more frequently observed in the paediatric context, but a delayed onset not exceptional both adulthood and elderly. However, whether paediatric-onset, adult-onset elderly-onset represent expressions of same continuum or different clinical entities still matter controversy. The aim this study to search for any differences demographic, features response treatment between pediatric-onset, disease.Subjects included were drawn from International AutoInflammatory Disease...
Objective The aim of this paper is to present the AutoInflammatory Disease Alliance (AIDA) international Registry dedicated Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic (VEXAS) syndrome, describing its design, construction, and modalities dissemination. Methods This a clinical, physician-driven, population- electronic-based instrument designed for retrospective prospective collection real-life data. Data gathering based on Research Electronic Capture (REDCap) tool intended obtain...
The aim of this paper is to point out the design, development and deployment AutoInflammatory Disease Alliance (AIDA) International Registry for paediatric adult patients with non-infectious uveitis (NIU).This a physician-driven, population- electronic-based registry implemented both retrospective prospective collection real-world demographics, clinical, laboratory, instrumental socioeconomic data other inflammatory ocular diseases recruited through AIDA Network. Data recruitment, based on...
Aim of this paper is to present the design, construction, and modalities dissemination AutoInflammatory Disease Alliance (AIDA) International Registry for patients with systemic juvenile idiopathic arthritis (sJIA) adult-onset Still's disease (AOSD), which are pediatric adult forms same autoinflammatory disorder.This a clinical, physician-driven, population- electronic-based instrument implemented retrospective prospective collection real-world data. The data based on Research Electronic...
Abstract Purpose of the present paper is to point out design, development and deployment AutoInflammatory Disease Alliance (AIDA) International Registry dedicated pediatric adult patients with Behçet’s disease (BD). The a clinical physician-driven non-population- electronic-based instrument implemented for retrospective prospective collection real-life data about demographics, clinical, therapeutic, laboratory, instrumental socioeconomic information from BD patients; based on Research...
Objective We aimed to evaluate the clinical usefulness of systemic score in prediction life‐threatening evolution Still disease. also assess relevance each component predicting and derive patient subsets accordingly. Methods A multicenter, observational, prospective study was designed including patients included Gruppo Italiano Di Ricerca Reumatologia Clinica e Sperimentale Adult‐Onset Disease Study Group Autoinflammatory Alliance Network Registry. Patients were assessed see if variables...
The mortality rate of patients with anti-neutrophil cytoplasm antibody -associated vasculitis (AAV) is higher than the general population. To date, no studies have evaluated factors associated unfavorable outcomes in Brazilian patients, who represent a miscegenated Our objective was to identify clinical and laboratory features AAV.One hundred twenty eight fulfilling American College Rheumatology Chapel Hill Classification Criteria followed between 2000 2018 our Outpatient Clinics were...
This article points out the design, methods, development and deployment of international registry promoted by AutoInflammatory Disease Alliance (AIDA) Network with aim to define assess paediatric adult patients immune-mediated scleritis. collects both retrospective prospective real-world data from non-infectious scleritis through Research Electronic Data Capture (REDCap) tool aims promote knowledge real-life evidence enrolled worldwide; also allows collection standardised data, ensuring...
The effectiveness of canakinumab may change according to the different times it is used after Still's disease onset. This study aimed investigate whether (CAN) shows differences in short- and long-term therapeutic outcomes, its use as lines biologic treatment.Patients included this were retrospectively enrolled from AutoInflammatory Disease Alliance (AIDA) International Registry dedicated disease. Seventy-seven (51 females 26 males) patients with present study. In total, 39 (50.6%) underwent...
To characterize clinical and laboratory signs of patients with Still's disease experiencing macrophage activation syndrome (MAS) identify factors associated MAS development. Patients classified according to internationally accepted criteria were enrolled in the AutoInflammatory Disease Alliance (AIDA) Registry. Clinical features observed during inflammatory attack complicated by included univariate multivariate logistic regression analysis A total 414 included; 39 (9.4%) them developed...
The present paper describes the design, development, and implementation of AutoInflammatory Disease Alliance (AIDA) International Registry specifically dedicated to patients with Schnitzler's syndrome.This is a clinical physician-driven, population- electronic-based registry implemented for retrospective prospective collection real-life data from syndrome; based on Research Electronic Data Capture (REDCap) tool, which designed collect standardized information research, has been realized...
To evaluate inactivated CoronaVac prime vaccination, antibody decay, booster dose, and safety in ANCA-Associated Vasculitis (AAV) patients.
Chronic invasive rhinosinusitis with facial bone damage is a common cause of functional and social impairment in granulomatosis polyangiitis (GPA) patients. To the best our knowledge, there no clinical or laboratory biomarker to predict damage. This case-control study included 90 patients GPA 270 health controls (HCs). Patients were categorized according presence tomographic erosions. Frequency RANKL osteoprotegerin single nucleotide polymorphisms (SNPs), analyzed by real-time polymerase...
Objectives: To describe clinical characteristics of patients with Still’s disease treated methotrexate (MTX) and to assess drug effectiveness evaluating change in activity, reduction inflammatory markers, glucocorticoid (GC)-sparing effect.Methods: Patients MTX were assessed among those included AIDA Network Still Disease Registry.Results: In this registry, 171 (males 43.3%, age 37.1±16.0 years) out 374 MTX. They mainly characterised by joint features fever without a prominent multiorgan...
Objectives Chronic invasive rhinosinusitis with bone damage is a common cause of functional and social impairment in patients granulomatosis polyangiitis (GPA). To the best our knowledge, there no clinical or laboratory biomarker to predict damage.Methods This case-control study included 90 GPA 270 health controls (HCs). Patients were divided according presence tomographic damage. Frequency RANKL osteoprotegerin single nucleotide polymorphisms (SNPs), analyzed by real-time polymerase chain...
Inflammatory myopathy with abundant macrophages (IMAM) is a rare entity and has been described in some systemic autoimmune diseases such as dermatomyositis lupus erythematous. To the best of our knowledge, IMAM not reported before juvenile erythematosus (jSLE).
Mortality of patients with ANCA-associated vasculitis (AAV) is higher than the general population. There are few papers in literature regarding factors associated this unfavorable outcome, most them eastern population or from nephrology centers. To date, there no study approach Latin-American patients, a miscegenated Our objective was to identify clinical and laboratory features mortality AAV.
Background: There are no reports focusing specifically on ANCA-associated vasculitis(AAV) vaccinated with COVID-19 vaccine. This condition raises special concern regarding SARS-CoV-2 complications due to its typical airway and kidney involvement. The aim of this study was evaluate CoronaVac immunogenicity safety in these patients, also assess the impact disease activity immunosuppressive drugs(IS) vaccine response.Method: We analyzed 53 naive AAV patients 106 controls from CoronavRheum phase...