Soad Hashad
A5058642529- Autoimmune and Inflammatory Disorders Research
- Adolescent and Pediatric Healthcare
- Family and Disability Support Research
- Inflammasome and immune disorders
- Systemic Lupus Erythematosus Research
- Kawasaki Disease and Coronary Complications
- Acute Lymphoblastic Leukemia research
- Ocular Diseases and Behçet’s Syndrome
- Immunodeficiency and Autoimmune Disorders
- Otitis Media and Relapsing Polychondritis
- Clinical practice guidelines implementation
- Rheumatoid Arthritis Research and Therapies
- Child and Adolescent Health
- Healthcare Systems and Technology
- Telemedicine and Telehealth Implementation
- Spondyloarthritis Studies and Treatments
- Immune Cell Function and Interaction
- Atherosclerosis and Cardiovascular Diseases
- Mechanical Circulatory Support Devices
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lymphadenopathy Diagnosis and Analysis
- Dupuytren's Contracture and Treatments
- Hidradenitis Suppurativa and Treatments
- Transplantation: Methods and Outcomes
- Pharmaceutical studies and practices
University of Tripoli
2021-2025
Tripoli Central Hospital
2014-2024
Children's Hospital
2022
Objective To compare the capacity of 2004 diagnostic guidelines for hemophagocytic lymphohistiocytosis (HLH‐2004) with preliminary systemic juvenile idiopathic arthritis (JIA)–associated macrophage activation syndrome (MAS) to discriminate MAS complicating JIA from 2 potentially confusable conditions, represented by active without and infection. Methods International pediatric rheumatologists hemato‐oncologists were asked retrospectively collect clinical information patients JIA–associated...
Abstract Background Juvenile idiopathic arthritis (JIA) is the most common rheumatologic disease of childhood. The Existing guidelines for polyarticular JIA are typically based on data from non-African populations and may not fully address unique challenges faced in African settings. We aimed to produce updated diagnosis treatment children adolescents with juvenile (poly-JIA). Methods This study was conducted aim reaching a consensus among experts poly-JIA using Delphi technique. first...
The spectrum of Juvenile Idiopathic Arthritis (JIA) in Africa is still largely unknown. We thus set out to illustrate how we up the PAFLAR JIA registry and describe clinical profile across various regions Africa. carried a retrospective observational cohort study where collaborators were trained on use existing REDCAP database enter data for patients currently under their care capturing epidemiological data, features, laboratory investigations, diagnosis therapy at initial diagnosis....
During the last decade, spondyloarthritis (SpA) has increasingly been considered a disease at crossroads between autoimmunity and autoinflammation. Some patients may even present with autoinflammatory-related manifestations, including fever, hidradenitis suppurativa, other neutrophilic dermatoses, an unusually high increase in inflammatory markers. Therefore, subgroup of SpA be identified, specific details about this cluster need to investigated. In regard, AutoInflammatory Disease Alliance...
The study objective was to compare the effectiveness of adalimumab (ADA) in monotherapy and combination with methotrexate (MTX) for paediatric noninfectious uveitis (NIU). Registry-based observational study. Children receiving ADA active were divided into group (group 1) plus MTX 2). Eighty four children enrolled (146 eyes): 22 1 (26.2%) 62 2 (73.8%). complete 48 (57.1%), partial 23 (27.4%) absent 4 (5.3%), without any differences across groups (p = 0.89). Fewer relapses per 100 PY occurred...
To describe tocilizumab (TCZ) effectiveness in 15 children with refractory non-infectious uveitis. Reported outcomes are the number of relapses before and after treatment, steroid-sparing effect drug retention rate. Macular oedema, fluorangiographic findings ocular complications also reported. The mean significantly decreased from 314 per 100 eyes/year to 106 (p=0.016). A significant was detected (p=0.037). TCZ survival 77.4% at 6 months, followed by 61.9% 12, 24 36 months follow-up. oedema...
To report the cumulative articular and extraarticular damage in Arab children with juvenile idiopathic arthritis (JIA) to identify variables that correlate disease damage.We conducted a multicenter, cross-sectional study among 14 pediatric rheumatology centers from 7 countries. JIA patients who met International League of Associations for Rheumatology classification criteria had duration >1 year were enrolled. Disease activity status was assessed using Juvenile Arthritis Multidimensional...
Hend Alkwai, M.D., Reem Alshammari, Abdwani, Muna Almutairi, Raed Alzyoud, Thaschawee Arkachaisri, Sumaira Farman, Soad Hashad, Rebecca James, Khulood Khawaja, Hala Lotfy, Swee Ping Tang, Soamarat Vilaiyuk, Sulaiman M Al-Mayouf, M.D.. J Rheum Dis -0001;0:. https://doi.org/10.4078/jrd.2023.0071
To evaluate the impact of family history autoimmune diseases (FHADs) on clinical characteristics and outcome juvenile idiopathic arthritis (JIA).We retrospectively reviewed children with JIA seen in 7 pediatric rheumatology clinics from 6 Arab countries. All included patients met International League Associations for Rheumatology classification criteria had a disease duration greater than 1 year. Data were collected at last follow-up visit comprised findings, including FHADs. Disease...
<title>Abstract</title> Background The spectrum of Juvenile Idiopathic Arthritis (JIA) in Africa is still largely unknown. We thus set out to describe the clinical-epidemiological profile across various regions Africa. Methods carried a retrospective observational cohort study where collaborators were trained on use existing PAFLAR REDCAP database enter data for JIA patients currently under their care capturing epidemiological data, clinical features, laboratory investigations, diagnosis and...
To assess concordance among criteria for inactive disease (ID) and low activity (LDA) in juvenile idiopathic arthritis (JIA) to seek factors driving discordance.The frequency of fulfillment existing was evaluated information on 10,186 patients extracted from 3 cross-sectional data sets. Patients were divided up according the functional phenotypes oligoarthritis polyarthritis. Concordance between examined using weighted Venn diagrams. The role each individual component explaining discordance...
The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient reported outcome measure that enables thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report results cross-cultural adaptation and validation parent patient versions JAMAR Libyan Arabic language. reading comprehension questionnaire was tested 10 JIA parents patients. Each participating centre asked to collect demographic, clinical data, 100 consecutive...
Abstract Background Macrophage Activation Syndrome (MAS) in Systemic Juvenile Idiopathic Arthritis (SoJIA) is a potentially life-threatening condition. The prevalence of MAS SoJIA population estimated to be 10%. However, reports suggested that the number patients with subclinical may as high 40%. Early recognition crucial because timely treatment important for survival. Objective To describe clinical and laboratory features associated Methods Data from cohort 38 without January 2006 2020...
Abstract Systemic juvenile idiopathic arthritis (sJIA) constitutes a small part of (JIA), yet has disproportionally higher rate mortality. In comparison to the other systemic many distinct clinical features that may be non-prominent and/or delayed manifestation. The Pediatric Rheumatology International Trial Organization (PRINTO), currently is developing new criterion for JIA classification which will allow better identification sJIA cases with onset and fail fulfil used League Against...
<h3>Background:</h3> The treatment for non-systemic Juvenile Idiopathic Arthritis (JIA) patients is guided by "treat to target" principle with progressive intensification of reach optimal disease control. It not known if patients' adverse event (AE) profile worsens, as their intensified. <h3>Objectives:</h3> Our goal was report AEs at least moderate intensity, serious AE and events special interest (ESI) in non-systemic-JIA they progressed from less intensive non-steroidal anti-inflammatory...
Systemic lupus erythematosus (SLE) is a chronic inflammatory multisystemic disease. Monitoring disease activity thoughtout the course important for effective management and assessment of outcome.
Objective We aimed to (1) evaluate the cardiac involvement, with a focus on myocarditis, in patients Still disease included multicenter Autoinflammatory Disease Alliance (AIDA) Network registry; and (2) assess predictive factors for myocarditis by deriving clinical risk patient profile this severe manifestation. Methods A observational study was established, which consecutive AIDA registry were characterized involvement. Cardiac involvement defined according presence of pericarditis,...
Abstract Background Telehealth use is increasing and will undeniably continue to play a role beyond the COVID-19 era. Best practice guidelines (BPG) for telehealth add credibility, standardize approaches, facilitate reimbursement, decrease liability. Objectives To develop BPG of In Rheumatology in Arab region, identify top barriers facilitators provide rheumatologists with practical toolkit implementation telehealth. Methods Guidelines were drafted by core steering committee from League...
Abstract Background Juvenile psoriatic arthritis (JPsA) is a relatively rare condition in childhood as it represents ∼5% of the whole Idiopathic Arthritis (JIA). There are fewer reports describing characteristics and outcome patients with JPsA. Aim To describe characteristic features treatment modalities JPsA among Libyan children pediatric rheumatology clinic at Tripoli Children Hospital which only referral covering western, northern southern part Libya to compare our results other...
Abstract Introduction Primary vasculitis syndromes are rare in childhood. The clinical manifestations depend on the vessels involved and can lead to significant mortality morbidity. Aim To study demographic characteristics of patients with diagnosed other than Kawazaki disease Henoch-Schonlein purpora (HSP) report outcome patients. Materials methods This is a case series conducted by reviewing files followed up at pediatric rheumatology unit Tripoli Children Hospital, Libya from year...