A5112843744- Hepatocellular Carcinoma Treatment and Prognosis
- Sarcoma Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Oral and Maxillofacial Pathology
- Eicosanoids and Hypertension Pharmacology
- Atrial Fibrillation Management and Outcomes
- Sepsis Diagnosis and Treatment
- Nerve injury and regeneration
- Antiplatelet Therapy and Cardiovascular Diseases
- Cancer, Hypoxia, and Metabolism
- Spaceflight effects on biology
- Advanced Malware Detection Techniques
- Anatomy and Medical Technology
- Network Security and Intrusion Detection
- Traumatic Brain Injury and Neurovascular Disturbances
- High Altitude and Hypoxia
- Cerebrospinal fluid and hydrocephalus
- ATP Synthase and ATPases Research
- Parkinson's Disease Mechanisms and Treatments
- Nuclear Receptors and Signaling
- Venous Thromboembolism Diagnosis and Management
- Digital and Cyber Forensics
- Pancreatic and Hepatic Oncology Research
- Intensive Care Unit Cognitive Disorders
- Appendicitis Diagnosis and Management
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
University of Electronic Science and Technology of China
2022-2024
Peking Union Medical College Hospital
2024
Soochow University
2023
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2022
Southern Medical University
2020
Parkinson's disease (PD) is a common neurodegenerative movement disorder characterized by dopaminergic neuron loss in the substantia nigra pars compacta and striatal dopamine depletion. The NUS1 gene, which encodes neurite outgrowth inhibitor B receptor (NgBR), has been recently identified as novel risk gene for PD. However, its roles mechanism neurodegeneration are still unclear. Here, we demonstrate that NgBR deficiency triggers neuronal damage through KAT7/RFX1/FGF1 axis. RNA sequencing...
Objective: To investigate the role and regulation mechanism of X box binding protein 1 (XBP1) for hypoxia/reoxygenation(H/R) injury in mouse renal tubular epithelial cells (TCMK-1) through thioredoxin interacting (TXNIP)-nucleotide-binding domain (NOD)-like receptor (TXNIP-NLRP3) signaling pathway. Methods: The were divided into 4 groups: si-NC group transfected with negative control siRNA (si-NC), si-XBP1 targeting XBP1 (si-XBP1), si-NC+H/R exposed to H/R, si-XBP1+H/R H/R. Annexin Ⅴ/PI...