Bibhuti Bhusan Champati

ORCID: 0000-0003-2792-0280
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Research Areas
  • Essential Oils and Antimicrobial Activity
  • Natural product bioactivities and synthesis
  • Andrographolide Research and Applications
  • Phytochemicals and Antioxidant Activities
  • Phytochemistry and Biological Activities
  • Medicinal Plants and Neuroprotection
  • Phytochemical Studies and Bioactivities
  • Ginseng Biological Effects and Applications
  • Streptococcal Infections and Treatments
  • Traditional Chinese Medicine Analysis
  • Traditional and Medicinal Uses of Annonaceae
  • Medicinal Plant Research
  • Dermatological and COVID-19 studies
  • Leaf Properties and Growth Measurement
  • Cancer therapeutics and mechanisms
  • Bioactive Compounds and Antitumor Agents
  • Nanoparticles: synthesis and applications
  • Plant biochemistry and biosynthesis
  • Ginger and Zingiberaceae research
  • Magnolia and Illicium research
  • Moringa oleifera research and applications
  • Computational Drug Discovery Methods
  • Synthesis and bioactivity of alkaloids
  • Morinda citrifolia extract uses
  • Laser-Ablation Synthesis of Nanoparticles

Siksha O Anusandhan University
2020-2024

Cinnamomum tamala (Buch.-Ham.) T.Nees & Eberm., or Indian Bay Leaf, is a well-known traditional ayurvedic medicine used to treat various ailments. However, the molecular mechanism of action essential oil (CTEO) against non-small cell lung cancer (NSCLC) remains elusive. The present study aims decipher targets and CTEO in treating NSCLC. GC-MS analysis detected 49 constituents; 44 successfully passed drug-likeness screening were identified as active compounds. A total 3961 4588...

10.1016/j.heliyon.2024.e28026 article EN cc-by-nc Heliyon 2024-03-01

Inside the biological milieu, nanoparticles with photocatalytic activity have potential to trigger cell death non-specifically due production of reactive oxygen species (ROS) upon reacting entities. Silver nanoparticle (AgNP) possessing narrow band gap energy can exhibit high light absorption property and significant activity. This study intends explore effects ROS generated AgNP on antimicrobial cytotoxic propensities. To this end, was synthesized using principle green chemistry from peel...

10.1002/tox.23787 article EN Environmental Toxicology 2023-03-29

Magnolia champaca (L.) Baill. ex Pierre of family Magnoliaceae, is a perennial tree with aromatic, ethnobotanical, and medicinal uses. The M. leaf reported to have myriad therapeutic activities, however, there are limited reports available on the chemical composition essential oil champaca. present study explored variation in yield isolated from 52 accessions Through hydrodistillation, was obtained, varied range 0.06 ± 0.003% 0.31 0.015% (v/w) fresh weight basis. GC-MS analysis identified...

10.3390/molecules27217302 article EN cc-by Molecules 2022-10-27

Elettaria cardamomum (L.) Maton (Zingiberaceae), commonly known as green or true cardamom, is a commercially important species, the seeds of which are extensively used in pharmaceutical, cosmetic and food industries. In spite increasing demand for cardamom essential oil international market, chemical profiling volatile compounds different plant parts not well explored. Though there few studies on characteristics its leaf from other phytogeographical regions, presence composition stems have...

10.1080/0972060x.2021.1937335 article EN Journal of Essential Oil Bearing Plants 2021-05-04

Andrographolide, the principal secondary metabolite of Andrographis paniculata, displays a wide spectrum medicinal activities. The content andrographolide varies significantly in species collected from different geographical regions. Therefore, this study aims at investigating role abiotic factors and selecting suitable sites for cultivation A. paniculata with high using multilayer perceptron artificial neural network (MLP-ANN) approach. A total 150 accessions regions Odisha West Bengal...

10.3390/molecules27092765 article EN cc-by Molecules 2022-04-26

The current research aims to elucidate the drug environment Interactions and predict a suitable growing condition for Bacopa monnieri (L.) Wettst with maximum bacoside A content using an artificial neural network (ANN) model. An experimental dataset was generated by collecting B. wild accessions from 81 locations across different geographical regions of eastern Indian (Odisha West Bengal). obtained ANN results specified that single hidden layer containing 11 neurons namely 13-11-1 structure...

10.1080/11263504.2022.2048278 article EN Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology 2022-03-02

Asparagus racemosus Willd. is a valuable medicinal plant which used all over the world. There are several marketed products of A. racemosus. The high demand for this herb has increased risk adulteration in its commercial products. adulterated herbal might pose serious ill effects on health. Therefore, it necessary to check quality terms presence their major bioactive compounds. present study aimed carry out qualitative and quantitative analysis Shatavarin IV through validated performance...

10.14719/pst.2206 article EN Plant Science Today 2023-03-19

The steroidal saponin, Shatavarin IV is the major bioactive compound present in root of Asparagus racemosus. contributes for a wide range biological activities like antioxidant, antitussive, antidyspepsia, antiulcer and anticancer activity. investigation aimed to identify five different species genus Asparagus. For very first time, was identified four densiflorus, setaceus, plumosus sprengeri. identification quantification done by HPTLC analysis. pre-coated silica gel 60 F254 plates were...

10.52711/0974-360x.2023.00429 article EN Research Journal of Pharmacy and Technology 2023-06-26

Andrographis paniculata (Burm. f.) Nees is a potential medicinal herb used to treat wide range of diseases. Various geographical origins this might lead the diversity herbal quality. The research aims establish chemical fingerprint for quality control and find out markers discrimination from different origin through chemometrics approach. A high performance liquid chromatography photo diode array method was developed simultaneous quantification five marker compounds establishing 28 locations...

10.36468/pharmaceutical-sciences.868 article EN Indian Journal of Pharmaceutical Sciences 2021-01-01

Bacopa monnieri (L.) Wettst is a very high-value medicinal plant that commonly used for improving cognitive functions. However, the availability of limited information on drying method B. has prompted to optimize suitable method. The present study therefore aimed evaluate influence following six treatments quality sample: microwave at 300 W and 600 W, hot air-drying 50°C 70°C, solar drying, freeze-drying (FD). attributes dried samples were comparatively analyzed in terms color, total color...

10.5114/bta.2021.111105 article EN cc-by-nc-nd BioTechnologia 2021-01-01

Andrographis paniculata is one of the most important medicinal plants having several pharmaceutical properties. Various products and raw powders this herb are sold in market. The high demand for A. poses problem adulteration their products. Therefore, it becomes necessary to check quality terms major bioactive compounds. In present study, marketed were analyzed assessment i.e. presence desired constituent, andrographolide. Ten tested showed A validated High Performance Thin Layer...

10.25303/1812rjbt067070 article EN Research Journal of Biotechnology 2023-11-05

Abstract Andrographis paniculata is an Indian medicinal plant with tremendous therapeutic values due to the presence of active diterpenoids in its aerial parts. However, high domestic and export demand has led overexploitation wild populations this species. With a view bringing A. into cultivation reduce pressure on populations, present study was undertaken identify elite germplasm from different locations eastern India by analysing intraspecific variation content four major diterpenoids. A...

10.1017/s1479262121000575 article EN Plant Genetic Resources 2021-12-01
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