A5045847080- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiac Arrest and Resuscitation
- Cardiac pacing and defibrillation studies
- Aortic aneurysm repair treatments
- Health Systems, Economic Evaluations, Quality of Life
- Transplantation: Methods and Outcomes
- Cardiac Imaging and Diagnostics
- Pulmonary Hypertension Research and Treatments
- Cardiomyopathy and Myosin Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Neuroendocrine Tumor Research Advances
- Neuroblastoma Research and Treatments
- Breast Implant and Reconstruction
- Pituitary Gland Disorders and Treatments
- Delphi Technique in Research
- Statistical Methods in Clinical Trials
- Blood Pressure and Hypertension Studies
- Infectious Aortic and Vascular Conditions
Erasmus University Rotterdam
2017-2025
Erasmus MC
2017-2025
Centre Hospitalier Universitaire de Rennes
2025
Sorbonne Université
2025
Valve (United States)
2025
Lung Institute
2025
Rotterdam University of Applied Sciences
2020
In the third report of European Registry for Patients with Mechanical Circulatory Support Association Cardio-Thoracic Surgery, outcomes patients receiving mechanical circulatory support are reviewed in relation to implant era.Procedures adult (January 2011-June 2020) were included. from centres <60% follow-ups completed excluded. Outcomes stratified into 3 eras (2011-2013, 2014-2017 and 2018-2020). Adverse event rates (AERs) calculated early phase (<3 months) late (>3 months). Risk factors...
Abstract OBJECTIVES This fourth report aimed to provide insights into patient characteristics, outcomes, and standardized outcome ratios of patients implanted with durable Mechanical Circulatory Support across participating centers in the European Registry for Patients (EUROMACS) registry. METHODS All registered receiving mechanical circulatory support up August 2024 were included. Expected number events predicted using penalized logistic regression. Standardized (Observed/Expected events)...
Abstract Aims Sufficient myocardial recovery with the subsequent explantation of a left ventricular assist device (LVAD) occurs in approximately 1–2% cases. However, follow‐up data about this condition are scarcely available literature. This study aimed to report long‐term outcomes and clinical management following LVAD explantation. Methods results An analysis European Registry for Patients Mechanical Circulatory Support was performed identify all adult patients successful Pre‐implant...
Tricuspid regurgitation (TR) is a frequent and complex problem, commonly combined with left-sided heart disease, such as mitral regurgitation. Significant TR associated increased mortality if left untreated or recurrent after therapy. was historically often disregarded remained undertreated. Surgery currently the only Class I Guideline recommended therapy for TR, in form of annuloplasty, leaflet repair, valve replacement. As growing experience transcatheter structural many dedicated...
Abstract OBJECTIVES Data on the impact and course of uncorrected tricuspid regurgitation (TR) during left ventricular assist device (LVAD) implantation are scarce inconsistent. This study explores clinical natural TR in patients after LVAD implantation. METHODS The European Registry for Patients with Mechanical Circulatory Support was used to identify adult implants without concomitant valve surgery. A mediation model developed assess association 30-day mortality via other risk factors....
To explore male-female differences in aneurysm growth and clinical outcomes a two-centre retrospective Dutch cohort study of adult patients with ascending aortic (AscAA). Adult whom imaging an AscAA (root and/or ascending: ≥40 mm) was performed between 2007 2022 were included. Aneurysm analysed using repeated measurements at the sinuses Valsalva (SoV) tubular aorta. Male-female explored presentation, characteristics, treatment strategy, survival, outcomes. One thousand eight hundred...
Observed patient survival after cardiothoracic interventions should ideally be placed in the context of matched-general-population survival. This study outlines several methodologies matching general population mortality to sample, subsequently calculating cumulative survival, highlighting their respective advantages, disadvantages, and limitations. A multicenter data set containing Ross procedure was used for methodological illustration. General extracted from country-specific life tables...
Abstract Objective Aortic valve repair/sparing have been established as effective treatments for aortic regurgitation and/or aneurysms. However, concerns remain regarding long-term durability, reproducibility, and patient selection. This study aims to asses clinical echocardiographic outcomes, with a focus on grade left ventricular ejection fraction evolution, in adults undergoing these procedures. Methods Adult patients the Heart Valve Society Database, any technique were included....
Proof-of-concept to determine the direct biomechanical effects of cardiac contractility modulation (CCM) on living myocardial slices (LMS) from patients with end-stage heart failure (HF). Left ventricular LMS HF were produced and cultured in a biomimetic system mechanical loading electrical stimulation. CCM stimulation (80 mA, 40 ms delay, 21 duration) enhanced maximum contractile force (CCM: 1229 µN (587-2658) vs. baseline: 1066 (529-2128), p = 0.05) area under curve 297 (151-562) 243...
Globally significant variation in treatment and course of heart valve disease (HVD) exists, outcome measurement is procedure focused instead patient focused. This article describes the development a patient-related (International Consortium for Health Outcomes Measurement) standard set outcomes case mix to be measured patients with HVD. A multisociety working group was formed that included representatives from scientific cardiology cardiothoracic surgery societies publish current guidelines...
Globally significant variation in treatment and course of heart valve disease (HVD) exists, outcome measurement is procedure focused instead patient focused. This article describes the development a patient-related (International Consortium for Health Outcomes Measurement) standard set outcomes case mix to be measured patients with HVD. A multisociety working group was formed that included representatives from scientific cardiology cardiothoracic surgery societies publish current guidelines...
Tricuspid regurgitation (TR) is common in patients receiving a left ventricular assist device (LVAD). Controversy exists as to whether concomitant tricuspid valve surgery (TVS) beneficial currently treated patients. Therefore, our goal was investigate the effect of TVS with LVAD implant.The European Registry for Patients Mechanical Circulatory Support used identify adult Matched and without were compared using propensity score matching strategy.In total, 3323 underwent implantation which 299...
Many patients undergoing durable left ventricular assist device (LVAD) implantation suffer from chronic kidney disease (CKD). Therefore, we investigated the effect of LVAD support on CKD.A retrospective multicenter cohort study, including all (HeartMate II (n = 330), HeartMate 3 22) and HeartWare 48) implantation. In total, 227 (56.8%) were implanted as bridge-to-transplantation; 154 (38.5%) destination therapy; 19 (4.7%) bridge-to-decision. Serum creatinine measurements collected over a...
Renal denervation (RDN) proved to significantly lower blood pressure (BP) at 2-6 months in patients on and off antihypertensive drugs. Given a lack of longer-term follow-up data, our aim was assess the safety efficacy RDN up five years taking into account drug regimen changes over time.In present single-center study, underwent for (therapy resistant) hypertension. Patients protocolized yearly out years. Data were collected 24-h ambulatory BP office monitoring, renal function, regimen,...
Globally significant variation in treatment and course of heart valve disease (HVD) exists, outcome measurement is procedure focused instead patient focused. This article describes the development a patient-related (International Consortium for Health Outcomes Measurement) standard set outcomes case mix to be measured patients with HVD. A multisociety working group was formed that included representatives from scientific cardiology cardiothoracic surgery societies publish current guidelines...
Abstract BACKGROUND Globally significant variation in treatment and course of heart valve disease (HVD) exists, outcome measurement is procedure focused instead patient focused. This article describes the development a patient-related (International Consortium for Health Outcomes Measurement) standard set outcomes case mix to be measured patients with HVD. METHODS A multisociety working group was formed that included representatives from scientific cardiology cardiothoracic surgery societies...