A5101589070- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Ferroptosis and cancer prognosis
- RNA modifications and cancer
- Circular RNAs in diseases
- Cancer Genomics and Diagnostics
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Research and Treatments
Shanghai Tenth People's Hospital
2017-2022
Tongji University
2017-2022
Hepatocellular carcinoma (HCC) is one of the deadliest malignant tumors that are harmful to human health. Increasing evidence has underscored critical role competitive endogenous RNA (ceRNA) regulatory networks among various cancers. However, complexity and behavior characteristics ceRNA network in HCC were still unclear. In this study, we aimed clarify a phosphatase tensin homolog (PTEN)-related identify potential prognostic markers associated with HCC. The expression profiles three RNAs...
Objective This study aims to explore the expression pattern and prognostic significance of miR-33a in non-small cell lung cancer (NSCLC) treated with adjuvant chemotherapy. Methods MiR-33aexpression NSCLC was analyzed silico using GEO database subsequently confirmed by quantitative RT-PCR 147 biopsies. Among these, 32 these biopsies were paired adjacent non-neoplastic tissues. The survival analysis Kaplan-Meier estimates stratified based on expression. In addition, multivariate corresponding...
MicroRNA (miR)‑125a‑3p is derived from the 3'‑end of pre‑miR‑125a, which associated with several types cancer, such as gastric and prostate glioma. The aim present study was to identify prognostic significance miR‑125a‑3p expression levels in patients NSCLC. gene omnibus database used analyze NSCLC silico, 148 samples 30 adjacent normal lung tissue specimens were analyzed for by qPCR. results showed that tissues higher than level tissues. There clinical parameters demonstrated be expression,...
To investigate the expression level of microRNA-101-3p (miR-101-3p) and its possible association with progression, prognosis chemotherapy in patients non-small cell lung cancer (NSCLC), Gene Expression Omnibus (GEO) database was used. Quantitative polymerase chain reaction used to verify 327 NSCLC 42 adjacent normal tissues, which viable tissues were paired nearby tissues. Based on Cox regression model, univariate multivariate analyses address factors that had effects overall survival (OS)...
Background: Dysregulation of microRNAs (miRNAs) in papillary thyroid cancer (PTC) might influence prognosis PTC. This study is aimed to develop a risk score system for predicting Methods: The miRNA and gene expression profiles PTC were obtained from Cancer Genome Atlas database. samples randomly separated into training set (n = 248) validation 248). differentially expressed miRNAs (DE-miRNAs) the screened using limma package. independent prognosis-associated DE-miRNAs identified building...