A5063753394- Psychedelics and Drug Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Chemical synthesis and alkaloids
- Nutrition and Health in Aging
- Parkinson's Disease Mechanisms and Treatments
- Balance, Gait, and Falls Prevention
- Health disparities and outcomes
- Global Health Care Issues
- Complementary and Alternative Medicine Studies
- Global Maternal and Child Health
- Grief, Bereavement, and Mental Health
- Neurological disorders and treatments
- Biochemical Analysis and Sensing Techniques
- Physical Activity and Health
- Child Nutrition and Water Access
- Functional Brain Connectivity Studies
- Frailty in Older Adults
- Restless Legs Syndrome Research
- Nutritional Studies and Diet
- Migration, Health and Trauma
- Economic and Financial Impacts of Cancer
- Long-Term Effects of COVID-19
- Health, psychology, and well-being
- Meta-analysis and systematic reviews
- Ophthalmology and Visual Impairment Studies
Johns Hopkins University
2016-2025
Johns Hopkins Medicine
2017-2025
Multidisciplinary Association for Psychedelic Studies
2025
University of Pittsburgh
2020-2024
Kelly Services (United States)
2024
National Cancer Institute
2019
University of Washington
2017
INCLIVA Health Research Institute
2017
Universitat de València
2017
Centro de Investigación Biomédica en Red de Salud Mental
2017
The burden of cardiovascular diseases (CVDs) remains unclear in many regions the world. GBD (Global Burden Disease) 2015 study integrated data on disease incidence, prevalence, and mortality to produce consistent, up-to-date estimates for burden. CVD was estimated from vital registration verbal autopsy data. prevalence using modeling software health surveys, prospective cohorts, system administrative data, registries. Years lived with disability (YLD) were by multiplying weights. life lost...
An understanding of the trends in tuberculosis incidence, prevalence, and mortality is crucial to tracking success control programmes identification remaining challenges. We assessed fatal non-fatal burden over past 25 years for 195 countries territories.
Rationale: Psychedelic research re-emerged from a period of suppression into the so-called psychedelic renaissance. In parallel, most media reporting has shifted overstatement risks psychedelics to overly positive hype. As empirical evidence is more equivocal than frequently portrayed, conclusions about effectiveness should be considered preliminary. Poor science communication psychedelics’ therapeutic potential may lead participants or patients feel misled and policy decisions misinformed....
Research has demonstrated both risks and benefits to using psychedelics as a therapeutic intervention for variety of mental health conditions. In recent years, the public discourse around psychedelic treatments been largely positive focused on more than risks. We believe field would benefit from balanced attention well within scientific community broader public. Coverage science swung between pendulum extremes, fearmongering in past decades effusive optimism today. Public about can should...
Randomized controlled trials (RCTs) are considered the gold standard for demonstrating efficacy of a treatment or intervention; however, RCT study design alone is insufficient to prevent all forms bias. In this paper, we review conflicts interest and other biases that pose challenges methodological rigor psychedelic RCTs, explore recommended bias mitigation measures. We focus on special relevance RCTs methods mitigating believe actionable urgent practices implement in research: (1)...
Background Cancer screening in the USA is suboptimal, particularly for individuals living vulnerable communities. This study aimed to understand how rurality and racial segregation are independently interactively associated with cancer fatalism. Methods We used data from a nationally representative sample of adults (n=17 736) National Institute’s Health Information Trends Survey, 2011–2017, including (colorectal, breast, cervical, prostate) among eligible participants These were linked...
Abstract Background The purpose was to examine whether longitudinal changes in self‐reported energy predict incident mobility disability and mortality. We further explored energy‐related behaviors (physical activity, appetite, or sleep quality) would explain these associations. Methods N = 2021 participants from the Health, Aging Body Composition Study free with at least three assessments years 2 10. Measurements outcomes were time first inability walk a quarter of mile (mobility disability)...
Declining energy and increasing fatigue, common in older age, predict neurodegenerative conditions, but their neural substrates are not known. We examined brain resting state connectivity relation to declining self-reported levels (SEL) occurrence of fatigue over time.
Abstract Background Effects of fatigue on health in older age are well studied, yet little is known about the clinical relevance energy perception. Aims To explore cross-sectional associations self-reported with physical and mental metrics Health, Aging, Body Composition Study. Methods Participants rated their from 0 to 10; outcome was dichotomized at median (≥ 7 = higher energy). Four domains were assessed: depressive symptoms (Center for Epidemiologic Studies Depression Scale); performance...
Recent discussions about the methodological rigor of psychedelic clinical trials have focused on potential underreporting or misreporting adverse events (AEs), with many calling for their systematic assessment to help mitigate these issues. In recent paper, Palitsky et al. offer a comprehensive framework AEs in psychedelic-assisted therapies, consideration spiritual, existential, religious, and theological impacts that psychedelics can have. this commentary, we respond al.’s proposal,...
Background: As classic psychedelics’ therapeutic potential is studied and their popularity continues to rise, it important establish relative risks benefits. Previous surveys have tended use convenience sampling on social media, select participants who had either extremely positive or negative effects, not compared the risk/benefit profile of psychedelics other substances. Aims: To address these limitations, we gathered samples from an opt-in panel service using quota-based approximate...
To identify potential differences between age-related macular degeneration (AMD) patients and controls in fall-relevant gait characteristics.Spatiotemporal characteristics using the GAITRite walkway were collected from 29 AMD 20 controls, aged 60 to 90 years, at Wilmer Eye Institute. Multiple linear regressions, controlling for age, sex, body mass index (BMI), comorbidities used assess associations AMD.Study participants predominantly white (86%) female (55%). Mean age of full study...
Abstract Background Mild parkinsonian signs (MPS), highly prevalent in older adults, predict disability. It is unknown whether energy decline, a predictor of mobility disability, also associated with MPS. We hypothesized that those MPS had greater decline self-reported level (SEL) than without MPS, and SEL share neural substrates. Method Using data from the Health, Aging Body Composition Study, we analyzed 293 Parkinson’s disease-free participants (83 ± 3 years old, 39% Black, 58% women)...
Overly restrictive clinical trial eligibility criteria can reduce generalizability, slow enrollment, and disproportionately exclude historically underrepresented populations. The for 196 Alzheimer's Disease Related Dementias (AD/ADRD) trials funded by the National Institute on Aging were analyzed to identify common their potential participants race/ethnicity. categorized type (48 Phase I/II pharmacological, 7 III/IV 128 non-pharmacological, diagnostic, 6 neuropsychiatric) target population...
Abstract Background Older adults reporting higher energy levels have better physical function. It is not known if these associations persist among older fatigue or associated with cognitive We examined longitudinal between self-reported energy, gait speed, and cognition, stratified by fatigue, in 2 613 participants (aged 74.6 ± 2.87 years) the Health, Aging Body Composition Study. Methods Self-reported (0–10, dichotomized at median) (present/absent) were measured baseline. Usual rapid-paced...
Welcome to Annals of Global Health,Annals Health is a peer-reviewed, fully open access, online journal dedicated publishing high quality articles all aspects global health. The journal's mission advance health, promote research, and foster the prevention treatment disease worldwide. Its goals are improve health well-being people, equity, wise stewardship earth's environment. latest impact factor 3.64.Annals supported by Program for Public Common Good at Boston College. It was founded in 1934...
Abstract While fatigue in older age is well studied, the clinical relevance of maintaining higher energy late life less understood. We explored associations self-reported with cognitive performance, depressive symptoms, and physical function Health, Aging Body Composition study (n=2,529, mean =75.9, 63.5% white, 44.9% men). Self-reported over past month was recorded from 0-10 (least to most energy) dichotomized at median (≥7=high energy). Cognitive performance measured using Modified...
Abstract Energy is an important concept in human health and diseases. Self-reported energy has been described as “the individual’s potential to perform physical mental activity” availability”. However, little empirical data exists on whether self-reported level related objectively measured level. Prior research suggests that more availability associated with higher activity It remains unclear would be level, such active expenditure total expenditure. Using from the Health, Aging Body...