A5070594888- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Intensive Care Unit Cognitive Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Pain Management
- Antibiotic Resistance in Bacteria
- Anesthesia and Sedative Agents
- Trauma and Emergency Care Studies
- Antibiotic Use and Resistance
- Nosocomial Infections in ICU
- Dialysis and Renal Disease Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Blood Coagulation and Thrombosis Mechanisms
- Nausea and vomiting management
- Cardiac Structural Anomalies and Repair
- Pharmaceutical studies and practices
- Central Venous Catheters and Hemodialysis
- Antifungal resistance and susceptibility
- Cardiac and Coronary Surgery Techniques
- Venous Thromboembolism Diagnosis and Management
- Antibiotics Pharmacokinetics and Efficacy
- Heart Failure Treatment and Management
- Renal function and acid-base balance
Smile Train
2024
Tunis El Manar University
2016-2024
Military Hospital of Tunis
2010-2024
Tunis University
2017-2022
Hôpital Militaire Moulay Ismail
2013-2020
Faculté de médecine de Tunis
2020
Hôpital Saint Eloi
2013
Université de Montpellier
2013
Children's Hospital
2006
Patients liberated from invasive mechanical ventilation are at risk of extubation failure, including inability to breathe without a tracheal tube (airway failure) or (non-airway failure). We sought identify respective factors for airway failure and non-airway following extubation.The primary endpoint this prospective, observational, multicenter study in 26 intensive care units was defined as need reintubation within 48 h extubation. A multinomial logistic regression model used...
Abstract Introduction Procalcitonin (PCT) biomarker is suggested to tailor antibiotic therapy in the medical intensive care unit (ICU) but studies perioperative medicine are scarce. The aim of this study was determine whether PCT reported thresholds associated with initial treatment response septic shock secondary intra-abdominal infection. Methods This single ICU, observational included patients shocks Demographics, at days 0, 1, 3, 5, and outcome were collected. Treatment failure death...
Mitochondrial dysfunction and consequent cellular energetic failure play a key role in the development of sepsis-related organs failure. Evidence suggests that pleiotropic effects levosimendan may positively affect metabolism during septic shock.To investigate changes concentration glucose, lactate, pyruvate, glycerol extracellular fluid skeletal muscle following administration patients with shock.The study was designed as prospective, double-blind, controlled, clinical pilot trial performed...
We describe a case of 58-year-old man with septic shock due to Carbapenem-resistant Klebsiella pneumoniae (CR-Kp) bloodstream infections (BSI) who was successfully treated high dose association amikacin and imipenem combined continuous venovenous hemodiafiltration (CVVHDF). A (Kp) isolated from the catheter culture two blood samples, drawn before removal peripheral vein. The Kp intermediate Amikacin (MIC = 16 μg/ml) resistant all other antibiotics including Imipenem 4 μg/ml), Colistin...
The aim of this study was to compare the effectiveness and safety ultrasound-guided out-of-plane internal jugular vein (OOP-IJV) in-plane supraclavicular subclavian (IP-SSCV) catheterization in adult intensive care unit.A total 250 consecutive patients requiring central venous catheterization, were randomly assigned undergo either OOP-IJV or IP-SSCV cannulation. All catheterizations carried out by three physicians. primary outcome first attempt success rate. Ultrasound scanning time,...
Background: Kodamaea ohmeri or Pichia is relatively rare yeast that belongs to ascomycete group and Saccharomycetaceae family. It recognized as an important pathogenic fungus in immunocompromised hosts. Methodology: Herein, we describe three cases where was isolated peripheral samples: nasal one case auricular two cases. The identification carried out by Vitek®2 YST ID card confirmed PCR sequencing. Susceptibility antifungal made E-test. Results: These yeasts were identified K. using...
Linezolid was introduced in clinical practice the early 2000s. It considered to be an ideal reserve drug for treatment of vancomycin-resistant Enterococcus spp. (VRE) and Staphylococcus aureus (VRSA). The aim our study describe evaluate use linezolid at intensive care unit (ICU) Tunisian military hospital. This is a thirty-month retrospective including patients treated with ICU Data collection realized using patients' medical files prescriptions. A pharmacist conducted extended medication...
Background. The detection of antiphospholipid antibodies (aPL) is interest because their importance in the pathogenesis arterial or venous thrombosis. They could be a “second hit” an inflammatory event such as infection. aim our study was to assess performance antibody biomarker predict in-hospital mortality intensive care unit (ICU) septic patients. Methods. We conducted prospective single-center observational including consecutive critically ill adults admitted unit. Clinical and...
ABSTRACT Introduction Injuries caused by terrorism attacks are one of the urgent problems society and health system. In this work, we aimed to assess injury severity score (ISS) trauma (TRISS) in Tunisian military combatants injured during attacks. Materials Methods A total 153 victims admitted Military Hospital Tunis between January 2012 2017 were included. Among them, 107 survived 46 died (43 at terrorist attack scene 3 hospital). All dead patients autopsied. Injury scores TRISSs then...
A prospective, observational, feasibility study was carried out on four patients with end-stage renal failure undergoing bicarbonate hemodialysis to the of an on-line hemodiafiltration technique using a citrate dialysate pre-dilutional infusion as for regional anticoagulation. All had contraindication systemic heparin The dialysis consisted without calcium Fresenius 4008S machine and Polysulfone F60 dialyzers. solution procured directly from infused into arterial line. To avoid risk...
Septic patients need a prompt normalization of macrohemodynamic parameters. Unfortunately, this optimization sometimes does not protect from organ failure development. in addition, there are data showing that microcirculatory dysfunction and Cellular metabolic alterations associated with mortality can fuel tissue distress leading to [1].
Mitochondrial dysfunction and consequent cellular energetic failure play a key role in the development of sepsis-related organs failure. Levosimendan, by calcium-sensitizing mechanism increases myocardial contractility while simultaneously exerting vasodilatory properties via activation ATP-dependent potassium channels (KATP) [1].
The study emphasizes the importance of high risk thromboembolism with inherited thrombophilic factors. Transesophageal echocardiography revealed large biatrial masses in an 87-year-old woman history nonvalvular atrial fibrillation, pulmonary embolism, and prescribed oral anticoagulation for prophylaxis embolic events. surgical removal presumed thrombus was declined by patient intravenous unfractionated heparin initiated. Treatment complicated additional events succumbed after 14 days due to...
Le syndrome d’hypersensibilité médicamenteuse ou <i>drug reaction with eosinophilia and systemic symptoms<i/> (DRESS) est une toxidermie grave associée à un nombre limité de médicaments. Il survient au bout d’une huit semaines traitement. Nous rapportons deux observations malades ayant développé DRESS, quatre après la prise carbamazépine réactivation virale cytomégalovirus. L’évolution était favorable l’arrêt du médicament incriminé, sous corticothérapie et traitement par ganciclovir. Au...
Autoimmune encephalitis is a dysimmune disease characterized by widely clinical polymorphism, ranging from the insidious onset of cognitive disorder to more complex forms with refractory status epilepticus. We are dealing here case limbic encephalitis, which initially presented sudden convulsions preceded essentially some psychiatric manifestations (episodes disorientation, mood and bizarre behaviors). The classic paraneoplastic investigation was negative. Cerebrospinal fluid (CSF) serum...