- Natural Language Processing Techniques
- Sleep and related disorders
- Cardiac Health and Mental Health
- Cancer survivorship and care
- Dementia and Cognitive Impairment Research
- Topic Modeling
- Pluripotent Stem Cells Research
- Sleep and Wakefulness Research
- Multimodal Machine Learning Applications
- Heart Rate Variability and Autonomic Control
- Circadian rhythm and melatonin
- Photoreceptor and optogenetics research
- Neuroscience and Neural Engineering
- Animal Genetics and Reproduction
- Ubiquitin and proteasome pathways
- Health, psychology, and well-being
- Schizophrenia research and treatment
- Sleep and Work-Related Fatigue
- Attention Deficit Hyperactivity Disorder
- Palliative Care and End-of-Life Issues
- Treatment of Major Depression
- Speech and dialogue systems
- Child and Adolescent Psychosocial and Emotional Development
- Health Systems, Economic Evaluations, Quality of Life
- Obsessive-Compulsive Spectrum Disorders
Leiden University
2025
Leiden University Medical Center
2025
San Diego State University
2017-2020
University of California, San Diego
2017-2020
La Jolla Alcohol Research
2017-2019
Mills (Norway)
2019
California Center for Sleep Disorders
2015
We present LaMDA: Language Models for Dialog Applications. LaMDA is a family of Transformer-based neural language models specialized dialog, which have up to 137B parameters and are pre-trained on 1.56T words public dialog data web text. While model scaling alone can improve quality, it shows less improvements safety factual grounding. demonstrate that fine-tuning with annotated enabling the consult external knowledge sources lead significant towards two key challenges The first challenge,...
Abstract Objective Depression is common among patients diagnosed with cancer. Patients cancer and depression use more health care services compared nondepressed patients. The current study seeks to estimate the added cost of in first year after diagnosis. Methods Health charges were obtained for 2051 depressed 11 182 an International Classification Diseases, Ninth Revision, diagnosis 2014 calendar from University California San Diego Healthcare System. annual without analyzed using...
Elevated blood pressure is a significant public health concern, particularly given its association with cardiovascular disease risk, including stroke. Caring for loved one Alzheimer has been associated physical morbidity, higher pressure. Engagement in adaptive coping strategies may help prevent elevation this population. This 5-year longitudinal study examined whether greater participation pleasant leisure activities was reduced caregivers.Participants were 126 in-home spousal Alzheimer's...
Depression in patients with cancer has been associated increased annual health care use and costs relative to nondepressed patients. Little is known of the potential cost savings receipt mental treatment. This study evaluated association between number visits comorbid major depression.
ABSTRACT Objective Older adults are among the most frequent users of emergency departments (EDs). Nonspecific symptoms, such as fatigue and widespread pain, common symptoms in patients admitted at ED. Interleukin 6 (IL-6) tumor necrosis factor α (TNF-α) inflammation biomarkers associated with chronic stress (i.e., dementia caregiving) nonspecific symptoms. This study aimed to determine whether IL-6 TNF-α were prospectively ED risk caregivers (CGs). Methods Participants 85 CGs, who reported...
The present study evaluated the psychometric properties of scores from Behavioral Activation for Depression Scale Short Form (BADS-SF) in a sample older age, spousal, Alzheimer’s caregivers participating an evaluation (BA) therapy compared to Information Support (IS) group. At baseline assessment, (N = 170) completed BADS-SF, which is comprised two subscales (Activation and Avoidance) that can be summed produce total score. Confirmatory factor analysis was used evaluate structural validity....