A5079761509- Sleep and Wakefulness Research
- Sleep and related disorders
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Sleep and Work-Related Fatigue
- Circadian rhythm and melatonin
- Heart Rate Variability and Autonomic Control
- Neural dynamics and brain function
- Advanced MRI Techniques and Applications
- Obstructive Sleep Apnea Research
- Transcranial Magnetic Stimulation Studies
- Neuroscience of respiration and sleep
- Optical Imaging and Spectroscopy Techniques
- Mind wandering and attention
- Stress Responses and Cortisol
- Pharmacy and Medical Practices
- Human-Automation Interaction and Safety
- Memory and Neural Mechanisms
- Motor Control and Adaptation
- Neuroscience and Music Perception
- Health and Well-being Studies
- Restless Legs Syndrome Research
- Physical Activity and Health
- Youth Substance Use and School Attendance
- Neuroscience and Neuropharmacology Research
Institut Universitaire de Gériatrie de Montréal
2019-2025
Concordia University
2019-2025
Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal
2019-2024
Macquarie University
2024
Woolcock Institute of Medical Research
2024
National University of Singapore
2024
University of Geneva
2018-2021
Sciences Cognitives et Sciences Affectives
2020
Centre National de la Recherche Scientifique
2018
Sorbonne Université
2018
Abstract The use of screen electronic devices in the evening negatively affects sleep. Yet, sleep is known to be essential for brain maturation and a key factor good academic performance, thus particularly critical during childhood adolescence. Although previous studies reported associations between time impairment, their causal relationship adolescents remains unclear. Using actigraphy daily questionnaires large sample students (12 19 years old), we assessed habits over 1 month. This...
Rocking has long been known to promote sleep in infants and, more recently, also adults, increasing NREM stage N2 and enhancing EEG slow waves spindles. Nevertheless, whether rocking promotes other species, what the underlying mechanisms are, yet be explored. In current study, C57BL/6J mice equipped with EMG electrodes were rocked laterally during their main period, i.e., 12-h light phase. We observed that affected a faster optimal rate than humans (1.0 versus 0.25 Hz). Specifically, at 1.0...
To provide a comprehensive assessment of sleep state misperception in insomnia disorder (INS) and good sleepers (GS) by comparing recordings performed for one night in-lab (PSG review) during several nights at-home (actigraphy diaries). Fifty-seven INS 29 GS wore an actigraphy device filled diary two weeks at-home. They subsequently completed PSG recording review in-lab. Sleep perception index (subjective/objective × 100) onset latency (SOL), duration (TST) wake were computed compared...
Nightmares are characterized by the experience of strong negative emotions occurring mainly during REM sleep. Some people suffer from nightmare disorder, which is defined repeated occurrence nightmares and significant distress in wakefulness. Yet, whether frequent relate to a general increase emotional reactivity or arousal sleep remains unclear. To address this question, we recorded heartbeat-evoked potentials (HEPs) wakefulness, NREM patients with disorder healthy participants. The HEP...
Sleep deprivation leads to significant impairments in cognitive performance and changes the interactions between large scale cortical networks, yet hierarchical organization of activity across states is still being explored. We used functional magnetic resonance imaging assess activations connectivity during tasks 20 healthy young adults, three states: (i) following a normal night sleep, (ii) 24hr total sleep deprivation, (iii) after morning recovery nap. Situating along organizing gradients...
Objectives: Our objective was to assess the effect of cognitive-behavioral therapy for insomnia (CBTi) on subjective and sleep quality (including spindles) cognition during a sedative-hypnotics withdrawal program in older adults with disorder. Methods: We performed two-arm randomised controlled trial (RCT) sedative-hypnotic plan alone (WPo group) or combined CBTi (WP+CBTi 47 disorder over sixteen-week period. primary outcomes were change self- reported severity (Insomnia Severity Index...
Objective: Investigate whether auditory closed-loop stimulation (CLAS) applied during sleep could be beneficial for and declarative memory in individuals with chronic insomnia. Methods: We performed a randomized crossover sham-controlled study on 27 insomnia to assess changes between night CLAS (i.e., 2-ON-OFF blocks tones locked slow wave up-states NREM) SHAM night. conducted assessments of (word paired-associate learning task) (morning questionnaire, polysomnographic recordings) both...
Specific brain oscillations can be manipulated during sleep to improve quality and memory performance. We previously demonstrated that continuous rocking stimulation (0.25Hz, lateral movement) applied good sleepers enhanced stable deep sleep, boosted NREM (spindles slow waves), consolidation. Here, we investigated whether nocturnal could benefit individuals suffering from difficulties. recruited sixteen young adults with subjective difficulties initiating and/or maintaining who presented...
ABSTRACT There is growing evidence in humans linking the temporal coupling between spindles and slow oscillations during NREM sleep with overnight stabilization of memories encoded from daytime experiences humans. However, whether type strength learning influence that relationship still unknown. Here we tested amount or verbal word‐pair prior to affects subsequent phase‐amplitude (PAC) (SO). We measured preferred timing such EEG 41 healthy human participants over a post‐learning control...
Sleep deprivation (SD) leads to impairments in cognitive function. Here, we tested the hypothesis that changes sleep-deprived brain can be explained by information processing within and between large-scale cortical networks. We acquired functional magnetic resonance imaging (fMRI) scans of 20 healthy volunteers during attention executive tasks following a regular night sleep, SD, recovery nap containing nonrapid eye movement (NREM) sleep. Overall, SD was associated with increased cortex-wide...
Abstract Motor imagery (MI) is known to engage motor networks and increasingly used as a relevant strategy in functional rehabilitation following immobilization, whereas its effects when applied during immobilization remain underexplored. Here, we hypothesized that MI practice 11 h of arm-immobilization prevents immobilization-related changes at the sensorimotor cortical representations hand, well on sleep features. Fourteen participants were tested after normal day (without immobilization),...
Evidence from animal and human research shows that established memories can undergo changes after reactivation through a process called reconsolidation. Alterations of the level stress hormone cortisol may provide way to manipulate reconsolidation in humans. Here, double-blind, within-subject design, we reactivated 3-d-old memory at 3:55 A.M. sixteen men four women, immediately followed by oral administration metyrapone versus placebo, examine whether metyrapone-induced suppression morning...
ABSTRACT Rationale High rates of insomnia in older adults lead to widespread benzodiazepine (BZD) and receptor agonist (BZRA) use, even though chronic use has been shown disrupt sleep regulation impact cognition. Little is known about sedative-hypnotic effects on NREM slow oscillations (SO) spindles, including their coupling, which crucial for memory, especially the elderly. Objectives Our objective was investigate effect macro-architecture, EEG relative power, as well SO spindle...
Abstract Simultaneous recording of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) is a very promising non‐invasive neuroimaging technique. However, EEG data obtained from the simultaneous EEG–fMRI are strongly influenced by MRI‐related artefacts, namely gradient artefacts (GA) ballistocardiogram (BCG) artefacts. When compared to GA correction, BCG correction more challenging remove due its inherent variabilities dynamic changes over time. The standard (i.e.,...
Sleep is essential for optimal functioning and health. Interconnected to multiple biological, psychological socio-environmental factors (i.e., biopsychosocial factors), the multidimensional nature of sleep rarely capitalized on in research. Here, we deployed a data-driven approach identify sleep-biopsychosocial profiles that linked self-reported patterns inter-individual variability health, cognition, lifestyle 770 healthy young adults. We uncovered five profiles, including two reflecting...
<title>Abstract</title> Sleep is essential for optimal functioning and health. Interconnected to multiple biological, psychological socio-environmental factors (i.e., biopsychosocial factors), the multidimensional nature of sleep rarely capitalized on in research. Here, we deployed a data-driven approach identify sleep-biopsychosocial profiles that linked self-reported patterns inter-individual variability health, cognition, lifestyle 770 healthy young adults. We uncovered five profiles,...
ABSTRACT Background Delayed recovery following cardiopulmonary exercise testing (CPET) is associated with cardiac morbidity and mortality. Recovery kinetics of oxygen uptake have not been described in people comorbid obstructive sleep apnea insomnia (COMISA) who an increased risk cardiovascular disease. Our objectives were to (a) describe heart rate (HRR), slopes (V˙O2/t), time half V˙O2max (T1/2) CPET COMISA; (b) investigate their response 8 weeks relaxation control intervention (Relax) or...
Insomnia treatment among individuals with comorbid insomnia and obstructive sleep apnea is suboptimal. In a pilot randomized controlled trial, 19 were allocated to one of two arms: EX + EX, consisting 8-week phases exercise training (EX), or RE CBTiEX, encompassing 8 weeks relaxation (RE) followed by combined cognitive-behavioral therapy (CBTiEX). Outcomes included Severity Index (ISI), polysomnography, cardiorespiratory fitness measures. A mixed-model analysis variance revealed Group × Time...
Decrease in cognitive performance after sleep deprivation followed by recovery suggests its key role, and especially non-rapid eye movement (NREM) sleep, the maintenance of cognition. It remains unknown whether brain network reorganization NREM stages N2 N3 can uniquely be mapped onto individual differences a nap following deprivation. Using resting state functional magnetic resonance imaging (fMRI), we quantified integration segregation networks during while participants took 1-hour 24-hour...
Abstract Simultaneous recording of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) is a widely used non-invasive neuroimaging technique in sleep studies. However, EEG data are strongly influenced by two types MRI-related artefacts: gradient artefacts (GA) ballistocardiogram (BCG). If correction suboptimal, the BCG obscures signals below 20Hz could make it difficult to investigate oscillations, especially spindles, specific oscillations occurring within 11-16Hz...