A5011642615- Advanced Drug Delivery Systems
- Liquid Crystal Research Advancements
- Essential Oils and Antimicrobial Activity
- Electrospun Nanofibers in Biomedical Applications
- Pomegranate: compositions and health benefits
- Business and Management Studies
- Surfactants and Colloidal Systems
- Tissue Engineering and Regenerative Medicine
- Bone Tissue Engineering Materials
- biodegradable polymer synthesis and properties
- Education and Digital Technologies
- Education Pedagogy and Practices
- Bone health and treatments
- Advanced Materials and Mechanics
- Nanoparticle-Based Drug Delivery
- Curcumin's Biomedical Applications
- Medical Imaging and Pathology Studies
- Phytoestrogen effects and research
- Antiplatelet Therapy and Cardiovascular Diseases
- Advancements in Transdermal Drug Delivery
- Phytochemistry and biological activity of medicinal plants
- Adenosine and Purinergic Signaling
- Plant Toxicity and Pharmacological Properties
- Seaweed-derived Bioactive Compounds
- Collagen: Extraction and Characterization
Universidade de Sorocaba
2014-2024
Universidade Estadual do Ceará
2020
The aim of this study was to investigate the influence extraction method on dry extract yield guava leaves, correlating total phenolic content (TPC) with antioxidant activity. extracts were obtained from hydroethanolic (50 and 70%) using ultrasound-assisted method. Folin-Ciocalteau reagent used determine TPC. DPPH (2,2-diphenyl-1-picrylhydrazyl) in vitro assay ability scavenge free radicals. results analyses demonstrated that produced a higher both (11%), contrast conventional 50% solvent...
Oral hyaluronic acid (HA) is a ubiquitous biopolymer that has gained attention as treatment for local or systemic diseases. Here, we prepared and characterized structures of free HA (f-HA) with high (>105 Da), intermediate (≤105 low (≤104 Da) average molar mass (MM); nanoparticles crosslinked adipic dihydrazide (n-HA); mixed formulations (mixed-HA) containing f-HA n-HA. MM distribution determined the structure, hydrodynamic diameter, zeta potential f-HAs. Crosslinking changed...
The design and development of an effective medicine are, however, often faced with a number challenges. One them is the close relationship drug's bioavailability solubility, dissolution rate permeability. use curcumin's (CUR) therapeutic potential limited by its poor water solubility low chemical stability. purpose was to evaluate effect polymer solid dispersion (SD) preparation techniques enhance aqueous stability CUR. recent patents on curcumin SD were reported as (i) polyvinylpyrrolidone...
Abstract The aim of this work was to develop a dense lamellar scaffold, as biomimetic material with potential applications in the regeneration tracheal tissue after surgical tumor resection. scaffolds were produced by plastic compression technique, exploiting use total phenolic compounds (TPC) from Psidium guajava Linn cross-linking agent polymeric mixture based on collagen (COL), silk fibroin (SF), and polyethylene glycol 400 (PEG 400). Fourier transform infrared spectroscopy (FTIR)...
The aim of this study was to develop a dense lamellar scaffolding composed by collagen (COL), silk fibroin (SF) and polyethylene glycol 400 (PEG 400) evaluate the influence freezing parameters (−80, −50, −18 °C) associated with its plastic compression. physicochemical characterization developed scaffolds done mechanical morphological properties. Fourier Transform Infrared Spectroscopy (FTIR) Differential scanning calorimetry (DSC) showed crosslinking between PEG polymers, change in COL...
Regenerative medicine is an emerging field that aims in healing damaged tissue. The choice of the crosslinking agent one most critical requirements for development three-dimensional scaffold devices. This study aimed to investigate effects proanthocyanidins (PA) and glutaraldehyde (GA) associated with plastic compression method on properties dense lamellar. physiomechanical physical–chemical scaffolds were evaluated. antioxidant activity was investigated by 2,2-diphenyl-1-picrylhydrazyl...
A mortalidade infantil é um indicador da qualidade assistência prestada a crianças ao redor do mundo, independente de classe social. As causas, quase sempre relacionadas algum aspecto materno ou gestacional, são consideradas simples prevenção e tratamento. Com isso, forma reduzir as taxas morbimortalidade, atenção à criança ganhou espaço dentre políticas públicas saúde. estratégia principal se desenvolveu através Programa Saúde Família acompanhamento sistemático que este sugere, com destaque...
Burns injuries induce a state of immunodepression that predisposes to bacterial infectious complication leads several comorbid diseases and high mortality rate. Previous studies about anti-inflammatory, antimicrobial antioxidant properties <em>Aloe vera</em> (L.) Burm., <em>Calendula officinalis</em> L. <em>Matricaria recutita</em> are acknowledge by effects.
The chemical processing of polymeric mixtures is a promising alternative for designing materials with new characteristics biomedical applications. This work proposed to produce and characterize obtained using polyethylene glycol (PEG400 or PEG4000) poly (L-co-D, L lactic acid)/PLDLA use. were prepared by the casting method. Characterizations performed Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), mechanical properties (perforation, resilience,...
<title>Abstract</title> Ulvan belongs to the class of sulfated heteropolysaccharide and is main component seaweed <italic>Ulva ohnoi</italic> (<italic>U. ohnoi</italic>). has a chemical structure similar fucoidan, chondroitin sulfate, hyaluronic acid, which are commonly used develop drug delivery systems. Due potential biomedical applications non-sulfated polysaccharides, this work aimed an environmentally friendly method for extracting ulvan from U. ohnoi with high yield purity. A novel...
This study has been undertaken to investigate the influence of copolymers poly-L-co-D, L-lactic acid (PLDLA) 70:30 and Poly (ethylene glycol)-block-poly (propylene glycol) (P407) in transmural transport 3'-azido-3'-deoxythymidine (azidothymidine (AZT), zidovudine).Based on anterior studies we use proximal duodenum evaluate, vitro, apparent intestinal permeability.The binary solid dispersion (SD) was prepared with, AZT, PLDLA, P407.The supercritical antisolvent (SAS) technique used obtain SD,...
Introdução : A histoplasmose pulmonar, conhecida também como “doença de Darling” e das cavernas” foi descrita pela primeira vez no Panamá entre 1905 1906 por Samuel Darling, onde necropsiou três quadros dissipados da doença Apresentação do caso: Paciente KDS, 41 anos idade, sexo feminino, natural procedente Goiânia, Goiás, com queixa tosse febre sendo aventado a hipótese pneumona tratado antimicrobianos. paciente não apresentou melhora quadro encaminhada para um serviço referência realizada...