A5076825501- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
- Advancements in Transdermal Drug Delivery
- Nanoparticles: synthesis and applications
- Electrospun Nanofibers in Biomedical Applications
- Estrogen and related hormone effects
- Nitric Oxide and Endothelin Effects
- Neuroendocrine regulation and behavior
- Reproductive System and Pregnancy
- Inflammatory mediators and NSAID effects
- Essential Oils and Antimicrobial Activity
- Central Venous Catheters and Hemodialysis
- Proteins in Food Systems
- Silk-based biomaterials and applications
- Wound Healing and Treatments
- Curcumin's Biomedical Applications
- Analytical Chemistry and Chromatography
- Tissue Engineering and Regenerative Medicine
- Nanocomposite Films for Food Packaging
- Public Health in Brazil
- Nanoparticle-Based Drug Delivery
- Research on Leishmaniasis Studies
- Parasites and Host Interactions
- Eicosanoids and Hypertension Pharmacology
- Fatty Acid Research and Health
Universidade de Sorocaba
2015-2024
Methodist University of Piracicaba
2005-2021
University of Somalia
2011-2021
Methodist University
2021
Universidade de São Paulo
2002-2017
Universidade Federal de São Carlos
2002-2013
Cambridge University Press
2009
New York University Press
2009
Universidade Federal de São Paulo
1999-2008
Consejo Nacional de Investigaciones Científicas y Técnicas
1986-1998
Polymer hydrogels have been suggested as dressing materials for the treatment of cutaneous wounds and tissue revitalization. In this work, we report development a hydrogel composed natural polymers (sodium alginate gelatin) silver nanoparticles (AgNPs) with recognized antimicrobial activity healing lesions. For hydrogel, different ratios sodium gelatin tested, while concentrations AgNO3 precursor (1.0, 2.0, 4.0 mM) were assayed production AgNPs. The obtained AgNPs exhibited characteristic...
Cosmetics composed of synthetic and/or semi-synthetic polymers, associated or not with natural exhibit a dashing design, thermal and chemo-sensitive properties. Cosmetic polymers are also used for the preparation nanoparticles delivery of, e.g., fragrances, purpose to modify their release profile reducing risk evaporation. Besides, other cosmetically active nutrients, dermal permeation enhancers, have been loaded into improve bioactivities on skin. The use in cosmetic formulations is...
Bacterial nanocellulose (BNC) has desirable properties for wound healing such as high purity, good shape retention, and water binding capacity. Bromelain is a protease found in pineapple tissues been applied several fields, it anti-inflammatory anticancer properties, promotes cell apoptosis, amongst others. In this work, BNC based device the controlled release of bromelain was developed. were submersed sterilized solution incubated at 25 °C under 100 rpm 24 h. Physical-chemical protein...
Cholinergic stimulation of vascular endothelin activates NO synthase (NOS), leading to generation from arginine. This diffuses the overlying smooth muscle and causes vasodilatation. NOS has also been found in central peripheral nervous systems it is clear now that plays an important role as a neurotransmitter. Here we investigate controlling contraction uterine muscle. Our previous work showed cyclooxygenase enzyme hypothalamus, production prostaglandin E2 (PGE2). We began by determining...
The properties of an Fe3+−peptide complex containing 5.6% Fe, obtained by the reaction ferric chloride with enzymatic hydrolysate casein, are described. major site iron binding corresponds primarily to carboxylate groups and a lesser extent peptide bonds. is insoluble at acid pH completely soluble neutral alkaline pH. When soluble, Fe3+ tightly bound mixture but can be displaced complexed low molecular weight ligand such as cysteine. Its efficacy in relation sulfate was compared rats. Both...
The regular intake of tomatoes or its products has been associated with a reduced risk chronic diseases and these effects have mainly attributed to lycopene. Here, we evaluated the anti-inflammatory properties lycopene protective on organ injury in two experimental models inflammation. In order study local inflammation, carrageenan-induced paw oedema model rats was performed. Lycopene administered as an acute (1, 10, 25 50 mg/kg, intraperitoneally, 15 min before carrageenan injection)...
Mucoadhesive membranes were proposed in this study as drug delivery system for betamethasone-17-valerate (BMV) the treatment of recurrent aphthous stomatitis (RAS). The obtained by using polymers chitosan (CHI) both presence and absence polyvinilpyrrolidone (PVP), following solvent evaporation method. PVP causes significant modifications its thermal properties. Changes events at 114 193 °C (related to BMV melting point), losses mass (39.38 30.68% CH:PVP CH:PVP-B, respectively), suggests...
The aim of this study was to develop a phytocosmetic sunscreen emulsion with antioxidant effect, containing blend flavonoid-enriched plant extracts. In vitro sun protection factor, activity, skin irritation, photostability, cutaneous permeation, and retention flavonoids were evaluated. Thermodynamically stable emulsions obtained tested for sensorial analysis after loading the selected when stored at low temperatures (5 °C), which 120 days concentration quercetin rutin above their limit...