A5036891893- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- CNS Lymphoma Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Monoclonal and Polyclonal Antibodies Research
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Healthcare and Venom Research
- Insect and Pesticide Research
- Chronic Myeloid Leukemia Treatments
- Immune Cell Function and Interaction
- Acute Lymphoblastic Leukemia research
- Insect Pest Control Strategies
- Sympathectomy and Hyperhidrosis Treatments
- Immunodeficiency and Autoimmune Disorders
- Ophthalmology and Eye Disorders
- Ocular Surface and Contact Lens
ACT Government
2019-2024
Australian National University
2013-2024
Canberra Hospital
2019-2024
University of Canberra
2022
Centenary Institute
2021
The Ohio State University Wexner Medical Center
2016-2020
Summary De novo diffuse large B‐cell lymphoma (DLBCL) presenting with synchronous central nervous system (CNS) and systemic disease (synDLBCL) is not well described excluded from clinical trials. We performed a retrospective analysis of 80 synDLBCL patients treated across 10 Australian UK centres. Of these patients, 96% had extranodal disease. CNS‐directed treatment combination intravenous cytarabine high‐dose methotrexate (“CNS‐intensive”) ( n = 38) was associated favourable survival...
Mutations of the IGH variable region in patients with chronic lymphocytic leukemia (CLL) are associated a favorable prognosis. Cytogenetic complexity (>3 unrelated aberrations) and translocations have been an unfavorable While mutational status IGHV is stable, cytogenetic aberrations frequently evolve. However, relationships these features as prognosticators at diagnosis unknown. We examined CpG-stimulated metaphase detected within one year CLL correlated outcome other clinical including...
To examine the potential utility of five multifocal pupillographic objective perimetry (mfPOP) protocols, in assessment early diabetic retinopathy (DR) and generalised diabetes-related tissue injury subjects with type 1 diabetes (T1D).Twenty-five T1D (age 41.8 ± 12.1 (SD) years, 13 male) either no DR (n = 13) or non-proliferative 12), 23 age gender-matched control 39.7 12.9 9 were examined by mfPOP using different stimulus methods differing visual field eccentricity (central 30° 60°), colour...
Abstract Background Despite recent advances, optimal therapeutic approaches applicable to subpopulations with primary central nervous system (CNS) lymphoma outside of clinical trials remain be determined. Methods We performed a retrospective study immunocompetent, adult patients histologically confirmed diffuse large B‐cell the CNS (PCNSL). 190/204 (93%) (median age: 65) received one five high‐dose methotrexate (HD‐MTX) containing chemotherapy regimens: MPV/Ara‐C (HD‐MTX, procarbazine, and...
Abstract Background Diffuse large B cell lymphoma (DLBCL) is the commonest that highly aggressive where one-third of patients relapse despite effective treatment. Interaction between cells and non-clonal immune within bone marrow microenvironment thought to play a critical role in pathogenesis DLBCL. Methods We used flow cytometry characterize proportion subpopulations ( N = 47) peripheral blood 54) 75 DLBCL at diagnosis study their impact on survival. Results Anergic (BM), characterized as...