A5026341453- Chemokine receptors and signaling
- Virology and Viral Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Immunotherapy and Immune Responses
- Systemic Sclerosis and Related Diseases
- Immunodeficiency and Autoimmune Disorders
- Eosinophilic Disorders and Syndromes
- Multiple Myeloma Research and Treatments
- SARS-CoV-2 and COVID-19 Research
Azienda Unita' Sanitaria Locale Di Modena
2024-2025
Multiple Myeloma (MM) typically originates from underlying precursor conditions, known as Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering (SMM). Validated risk factors, related to the main features clonal plasma cells, are employed in current prognostic models assess long-term probabilities progression MM. In addition, new immunologic parameters, measuring protective MM-specific T-cell responses, could help identify patients with shorter time-to-progression. this...
Abstract Background Upon infection activated plasma cells produce large quantities of antibodies which can lead to the emergence a monoclonal component (MC), detectable by serum protein electrophoresis (SPEP). This study aims investigate any correlation between SARS‐CoV‐2 and MC development and, if identified, whether it persists during follow‐up. Methods SPEPs 786 patients admitted hospitals March 01 2020 31 2022 were evaluated. Positive (SARS‐CoV‐2+) negative (SARS‐CoV‐2−) nasopharyngeal...