A5012849974- Cardiovascular Function and Risk Factors
- Ultrasound in Clinical Applications
- Heart Failure Treatment and Management
- Pulmonary Hypertension Research and Treatments
- COVID-19 Clinical Research Studies
- Cardiac Imaging and Diagnostics
- Heart Rate Variability and Autonomic Control
- Atrial Fibrillation Management and Outcomes
- Respiratory Support and Mechanisms
- Hepatocellular Carcinoma Treatment and Prognosis
- Cardiac electrophysiology and arrhythmias
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Health and Disease Prevention
- Sepsis Diagnosis and Treatment
- Phonocardiography and Auscultation Techniques
- Cardiac Arrhythmias and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Congenital Heart Disease Studies
- Lipoproteins and Cardiovascular Health
- Cardiovascular and exercise physiology
- Optical Imaging and Spectroscopy Techniques
- SARS-CoV-2 and COVID-19 Research
- Renal function and acid-base balance
- demographic modeling and climate adaptation
- Intensive Care Unit Cognitive Disorders
University of Copenhagen
2020-2025
Gentofte Hospital
2020-2025
Copenhagen University Hospital
2024
Brigham and Women's Hospital
2020-2023
Frederiksberg Hospital
2022
Harvard University
2020-2021
Statens Serum Institut
2021
Rigshospitalet
2020-2021
By 9 December 2021, 785 SARS-CoV-2 Omicron variant cases have been identified in Denmark. Most were fully (76%) or booster-vaccinated (7.1%); 34 (4.3%) had a previous infection. The majority of with available information reported symptoms (509/666; 76%) and most infected Denmark (588/644; 91%). One five cannot be linked to cases, indicating widespread community transmission. Nine hospitalised, one required intensive care no deaths registered.
The present study had two aims: (i) compare echocardiographic parameters in COVID-19 patients with matched controls and (2) assess the prognostic value of measures left (LV) right ventricular (RV) function relation to related death.In this prospective multicentre cohort study, 214 consecutive hospitalized underwent an examination (by pre-determined research protocol). All participants were successfully 1:1 from general population on age, sex, hypertension. Mean age sample was 69 years, 55%...
BackgroundLung ultrasound (LUS) is a useful tool for diagnosis and monitoring in patients with active COVID-19-infection. However, less known about the changes LUS findings after hospitalization COVID-19.MethodsIn prospective, longitudinal study COVID-19 enrolled from non-ICU hospital units, adult underwent 8-zone blood sampling both during 2–3 months discharge. images were analyzed blinded to clinical variables outcomes.ResultsA total of 71 interpretable at baseline follow up (mean age 64...
Wall Motion Score Index (WMSI) is a simple method to quantify global and regional systolic function on echocardiography. We sought investigate the prognostic importance of WMSI for development incident heart failure (HF) in general population.We included adults without HF or ischemic disease from 4th Copenhagen City Heart Study (2001-2003). At baseline, participants underwent an echocardiography physical examination completed self-administered health questionnaire. was assessed by...
Abstract Aims We sought to examine sex differences in congestion patients hospitalized for acute heart failure (AHF). Understanding congestive patterns women and men with AHF may provide insights into the presentation prognosis of patients. Methods results In a prospective, two‐site study adults AHF, four‐zone lung ultrasound (LUS) was performed at time echocardiography baseline (LUS1) and, subset, pre‐discharge (LUS2). B‐lines on LUS echocardiographic images were analysed offline, blinded...
As lung ultrasound (LUS) has emerged as a diagnostic tool in patients with COVID-19, we sought to investigate the association between LUS findings and composite in-hospital outcome of ARDS incidence, ICU admission, all-cause mortality.In this prospective, multi-center, observational study, adults laboratory-confirmed SARS-CoV-2 infection were enrolled from non-ICU in-patient units. Subjects underwent an evaluating total 8 zones. Images analyzed off-line, blinded clinical variables outcomes....
Background In this study we aimed to assess if a focused lung ultrasound examination predicts the need for mechanical ventilation, admission an intensive care unit, high-flow oxygen treatment, death from COVID-19 within 30 days and 30-day all-cause mortality in patients with clinical suspicion of or PCR-verified SARS-CoV-2 infection. Methods A multicentre prospective cohort trial was performed. Film clips examinations were recorded rated by blinded observers using different scoring systems....
Pulmonary vascular abnormalities, quantified from computed tomography scans, have frequently been observed in patients with pulmonary diseases. However, little is known about changes cardiac disease. Thus, we aimed to examine the cardiopulmonary relation atrial fibrillation (AF) by comparing volume (PVV) echocardiographic measures and AF severity. A total of 742 (median age 63 years, 70% men) who underwent ablation for were included. Preprocedural was used measure small-vessel PVV, along...
Abstract Aim To promote the implementation of right ventricular (RV) longitudinal strain in clinical practice, we sought to propose normal values for RV free wall (RVFWLS) and four-chamber (RV4CLS) investigate association with echocardiographic parameters participants from general population. Methods Results Participants 5th Copenhagen City Heart Study (2011–2015)—a prospective cohort study—with available measurements were included. RVFWLS RV4CLS assessed using two-dimensional...
Of the more than 550,000 patients receiving maintenance hemodialysis (HD) in United States, each has an average of 1.6 admissions annually (>880,000 inpatient HD sessions). Little is known about temporal changes laboratory values, ECGs, and intravascular extravascular volume during sessions.In this prospective cohort study hospitalized patients, we assessed intradialytic values (metabolic panels, blood gases, ionized calcium levels), sonographic measures status.Among 30 participants...
The cardiac time intervals include the isovolumic contraction (IVCT), left ventricular ejection (LVET), relaxation (IVRT) and combination of all in myocardial performance index (MPI) (defined as [(IVCT+IVRT)/LVET)]. Whether change over which clinical factors that accelerate these changes is not well-established. Additionally, whether are associated with subsequent heart failure (HF), remains unknown.We investigated participants from general population (n = 1064) who had an echocardiographic...
Abstract Aims Right ventricular free wall (RVFWLS) and four-chamber longitudinal strain (RV4CLS) are associated with adverse events in various patient populations including patients heart failure (HF). We sought to investigate the prognostic value of RVFWLS RV4CLS for development incident HF participants from general population. Methods results Participants 5th Copenhagen City Heart Study (2011–2015) without known chronic ischaemic disease or at baseline were included. obtained using...
Abstract Background Lipoprotein(a) [Lp(a)] is a genetically determined risk factor for myocardial infarction and aortic valve stenosis, elevated Lp(a) levels are associated with increased of heart failure. While part this failure mediated through atherosclerotic valvular disease, other pathological pathways may also contribute to the association between Purpose To assess if corresponding LPA genotypes echocardiographic measures left ventricular structure function in general population....
Abstract Background B-lines on lung ultrasound (LUS) are non-specific signs of increased density within tissue, which can be secondary to pulmonary congestion, pneumonia, or fibrosis. LUS is recommended for managing acute heart failure (HF); however, its value in non-HF populations less clear. Purpose To identify clinical, laboratory, and echocardiographic predictors a population with Coronavirus disease 2019 (COVID-19). Methods In the ECHOVID-19 study, hospitalized non-ICU patients ≥18...
Abstract Background Frailty is a major risk factor for adverse cardiovascular events. Influenza vaccination has been shown to protect against fatal and nonfatal However, limited data exist on the added benefit of high-dose versus standard-dose influenza according frailty status. Purpose We sought assess relative effectiveness (QIV-HD) (QIV-SD) quadrivalent status in elderly individuals. Methods This post-hoc analysis randomized controlled feasibility trial QIV-HD QIV-SD conducted during...