A5100636749- Catalytic C–H Functionalization Methods
- Chemical Synthesis and Analysis
- Synthetic Organic Chemistry Methods
- Chemical Synthesis and Reactions
- Click Chemistry and Applications
- Chemical Reaction Mechanisms
- Crystal structures of chemical compounds
- Sulfur-Based Synthesis Techniques
- Inorganic and Organometallic Chemistry
- Oxidative Organic Chemistry Reactions
- Asymmetric Hydrogenation and Catalysis
- Organic Chemistry Cycloaddition Reactions
- Catalytic Alkyne Reactions
- Multicomponent Synthesis of Heterocycles
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Synthesis and biological activity
- Catalytic Cross-Coupling Reactions
- Fluorine in Organic Chemistry
- Synthesis and Catalytic Reactions
- Synthesis of heterocyclic compounds
- Asymmetric Synthesis and Catalysis
- Protein Degradation and Inhibitors
First Affiliated Hospital of Henan University
2022
Tianjin University
2020
Peking University
2010-2018
Tsinghua University
2016
Shenyang University of Technology
2015
Nankai University
2009
Central China Normal University
2005
Acidity effect: Correlations of pKa with catalytic activity and stereoselectivity were determined linear free energy relationships (LFERs) observed for both pKa−log (k) (R/S) correlations in meta- and/or para-substituted aromatic thioureas (see figure). These results provided a basis new catalyst development several improved catalysts identified our initial attempts. Detailed facts importance to specialist readers are published as "Supporting Information". Such documents peer-reviewed, but...
MeOTf-catalyzed arylalkyne–aldehyde metathesis and Nazarov cyclization represent a sustainable atom-economical approach for the construction of indanones with high stereoselectivity.
A one-pot palladium-catalyzed synthesis of fluoronones via decarboxylative cyclization is reported. This protocol offers good yields and tolerates a broad range functional groups. Based on the extensive experimental data, we propose plausible insertion mechanism.
Benefiting from their unique properties, the development of structurally novel and easily accessible medium rings is significant interest in pharmaceutical industry academic research. However, synthetic access to medium-ring scaffolds very difficult due rigid skeleton large-angle strains. In this paper, a new class bearing bitriazolyls (MRBTs) was designed, synthesized, identified as promising ligand for Cu(I)-catalyzed click reaction, used site-special modification protein. One MRBTs, 3aa,...
The highly selective title reaction affords tetrahydroquinoline derivatives under mild conditions using O2 as oxidant.
A series of novel 1,4-bis(alkynyl)benzene derivatives were synthesized from trimethylsilyl-substituted alkynes by the mediation zirconocene with excellent regioselectivity in high yields. The 3,6-bis(trimethylsilyl)-4,5-dialkylphthalic acid dimethyl esters prepared cycloaddition 2,5-bis(trimethylsilyl)zirconacyclopentadienes to acetylenedicarboxylate. After iodination iodine monochloride, 3,6-diiodo-4,5-dialkylphthalic reacted terminal prepare corresponding Sonogashira coupling reactions....
Abstract C 34 H 36 N 4 O 5 , monoclinic, 2/ c (no. 15), a = 29.9636(9) Å, b 20.4000(3) 14.2266(4) β 132.845(5)°, V 6376.0(5) Å 3 Z 8, R gt ( F ) 0.0544, wR ref 2 0.1735, T 293(2) K.