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Contact & Profiles
Research Areas
- Trauma and Emergency Care Studies
- Maternal and fetal healthcare
- Biochemical Analysis and Sensing Techniques
- Regulation of Appetite and Obesity
- Maternal and Perinatal Health Interventions
- Receptor Mechanisms and Signaling
Johns Hopkins University
2012-2018
Johns Hopkins Medicine
2018
Abstract The orexigenic neuropeptide melanin‐concentrating hormone (MCH) is well positioned to play a key role in connecting brain reward and homeostatic systems due its synthesis hypothalamic circuitry receptor expression throughout the cortico‐striatal circuit. Here we examined whether targeted‐deletion of MCH (MCH‐1R) gene‐targeted heterozygote knockout mice (KO), or systemic treatment with pharmacological agents designed antagonise MCH‐1R C57BL/6J would disrupt two putative consequences...
10.1111/j.1460-9568.2012.08207.x
article
EN
European Journal of Neuroscience
2012-07-09
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