A5048848751- Thyroid and Parathyroid Surgery
- Parathyroid Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Diversity and Career in Medicine
- Pancreatic and Hepatic Oncology Research
- Neuroblastoma Research and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Pituitary Gland Disorders and Treatments
- Lung Cancer Research Studies
- Thyroid Disorders and Treatments
- Genetic Syndromes and Imprinting
- Medical Imaging and Pathology Studies
- Health and Medical Research Impacts
- Head and Neck Anomalies
- Adrenal and Paraganglionic Tumors
- Innovations in Medical Education
- Surgical Simulation and Training
- Developmental Biology and Gene Regulation
- Hedgehog Signaling Pathway Studies
- Cancer, Hypoxia, and Metabolism
- Healthcare cost, quality, practices
- Global Health Workforce Issues
- Hormonal Regulation and Hypertension
- Bone health and treatments
University of Alabama at Birmingham
2016-2025
American Journal Experts (United States)
2024-2025
Johns Hopkins Medicine
1995-2024
Johns Hopkins University
1995-2024
University of Utah
2024
Mayo Clinic in Florida
2023
American Association of Neurological Surgeons
2023
American College of Surgeons
2005-2023
Linde (United States)
2023
Twitter (United States)
2023
Background: Thyroid disease in pregnancy is a common clinical problem. Since the guidelines for management of these disorders by American Association (ATA) were first published 2011, significant and scientific advances have occurred field. The aim to inform clinicians, patients, researchers, health policy makers on evidence relating diagnosis thyroid women during pregnancy, preconception, postpartum period. Methods: specific questions addressed based prior versions guidelines, stakeholder...
Neuroendocrine tumors are a heterogeneous group of originating in various anatomic locations. The management this disease poses significant challenge because the clinical presentations and varying degrees aggressiveness. recent completion several phase 3 trials, including those evaluating octreotide, sunitinib, everolimus, demonstrate that rigorous evaluation novel agents is possible can lead to practice-changing outcomes. Nevertheless, there many aspects treatment neuroendocrine remain...
Pheochromocytomas, intra-adrenal paraganglioma, and extra-adrenal sympathetic parasympathetic paragangliomas are neuroendocrine tumors derived from adrenal chromaffin cells or similar in paraganglia, respectively. Serious morbidity mortality rates associated with these related to the potent effects of catecholamines on various organs, especially those cardiovascular system. Before any surgical procedure is done, preoperative blockade necessary protect patient against significant release due...
TSH is a known thyroid growth factor, but the pathogenic role of in oncogenesis unclear.The aim was to examine relationship between preoperative and differentiated cancer (DTC).The design retrospective cohort.Between May 1994 January 2007, 1198 patients underwent surgery at single hospital. Data from 843 with serum concentration were recorded.Serum measured sensitive assay. Diagnoses DTC vs. benign disease based on surgical pathology reports.Twenty-nine percent (241 843) had final pathology....
Objective: To develop evidence-based recommendations for safe, effective, and appropriate thyroidectomy. Background: Surgical management of thyroid disease has evolved considerably over several decades leading to variability in rendered care. Over 100,000 operations are performed annually the US. Methods: The medical literature from 1/1/1985 11/9/2018 was reviewed by a panel 19 experts disorders representing multiple disciplines. authors used best available evidence construct surgical...
In Brief Objective: The purpose of this study was to identify the risk factors that predict papillary thyroid microcarcinoma (PTMC)-related death in a large patient population determine which patients need aggressive treatment. Background: management PTMC is controversial and ranges from observation total thyroidectomy. lack consensus predominantly due general excellent overall prognosis, thereby requiring cohort delineate differences outcome. Methods: All cancer with tumor size 1 cm or less...
The achaete-scute genes encode essential transcription factors in normal Drosophila and vertebrate nervous system development. Human homolog-1 (hASH1) is constitutively expressed a human lung cancer with neuroendocrine (NE) features, small cell (SCLC), for development of the pulmonary NE cells that most resemble this neoplasm. Mechanisms regulating homolog expression outside are presently unclear, either context developing or neoplastic features. We now provide evidence protein...
In Brief Objective: To determine the utility of several perioperative adjuncts for parathyroid localization during surgery, we prospectively compared accuracy sestamibi–single photon emission computed tomography (SPECT) scanning, radioguided and intraoperative hormone (ioPTH) testing. Summary Background Data: Minimally invasive parathyroidectomy (MIP) is rapidly becoming procedure choice in patients with primary hyperparathyroidism (HPT). Several can be used to localize adenomas, including...
Medullary thyroid cancer accounts for 5%-10% of all cancers. The majority medullary cancers are sporadic, but 20% cases a result germline mutation in the ret proto-oncogene. Hereditary can be seen as part multiple endocrine neoplasia syndrome type 2A or 2B familial cancer. This article discusses current methods available diagnosis and evaluation patient with suspected management is predominantly surgical excision, consisting total thyroidectomy lymph node dissection. extent timing excision...
All thyroid nodules 4 cm or larger should be surgically removed regardless of fine-needle aspiration biopsy (FNAB) results because an unacceptably high rate false-negative preoperative in these large nodules.Retrospective cohort study.Single-institution, tertiary academic referral center.A retrospective analysis was performed on all patients who underwent surgery for a nodule from May 1, 1994, through January 31, 2007.Preoperative FNAB were correlated with final surgical pathologic results....