A5083798398- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Dental materials and restorations
- Additive Manufacturing and 3D Printing Technologies
- Facial Trauma and Fracture Management
- Orthopaedic implants and arthroplasty
- Laser-Ablation Synthesis of Nanoparticles
- Calcium Carbonate Crystallization and Inhibition
- Glass properties and applications
- 3D Printing in Biomedical Research
- Engineering Technology and Methodologies
- Collagen: Extraction and Characterization
- TiO2 Photocatalysis and Solar Cells
- Thermal and Kinetic Analysis
- Nanoplatforms for cancer theranostics
- Recycling and utilization of industrial and municipal waste in materials production
- Luminescence Properties of Advanced Materials
- Innovations in Concrete and Construction Materials
- Advanced Nanomaterials in Catalysis
- Advanced Radiotherapy Techniques
- Advanced Photocatalysis Techniques
- Graphene and Nanomaterials Applications
- Ocular Disorders and Treatments
- Pickering emulsions and particle stabilization
- Spaceflight effects on biology
Polytechnic University of Turin
2018-2023
National Interuniversity Consortium of Materials Science and Technology
2023
McGill University
2019
Tampere University
2019
Calcium phosphates (CaPs) are biocompatible and biodegradable materials showing a great promise in bone regeneration as good alternative to the use of auto- allografts guide support tissue critically-sized defects. This can be certainly attributed their similarity mineral phase natural bone. Among CaPs, hydroxyapatite (HA) deserves special attention it, actually is main inorganic component tissue. review offers comprehensive overview past current trends HA grafting material, with focus on...
Abstract Sol‐gel route has shown its enormous potential in tissue engineering applications as an advantageous method for the production of bioactive glasses aimed at regenerating both hard and soft tissues. This review discusses chemical aspects with emphasis on morphological, chemical, mechanical, biological properties sol‐gel derived materials. The attention will be particularly focused foam scaffolds bone regeneration. advantages deriving from versatility compared to traditional...
Abstract Bioactive glasses exhibit the unique ability of bone bonding, thus creating a stable interface by stimulating cells toward mechanisms regeneration and self‐repair activated ionic dissolution products. Therefore, 3D glass‐derived scaffolds can be considered ideal porous templates to used in tissue engineering strategies regenerative medicine. This review provides comprehensive overview all technological aspects relevant fabrication bioactive glass scaffolds, including fundamentals...
Abstract This work deals with the additive manufacturing and characterization of hydroxyapatite scaffolds mimicking trabecular architecture cancellous bone. A novel approach was proposed relying on stereolithographic technology, which builds foam‐like ceramic by using three‐dimensional (3D) micro‐tomographic reconstructions polymeric sponges as virtual templates for process. The layer‐by‐layer fabrication process involves selective polymerization a photocurable resin in particles are...
Bioactive sol-gel glasses are attractive biomaterials from both technological and functional viewpoints as they require lower processing temperatures compared to their melt-derived counterparts exhibit a high specific surface area due inherent nanoporosity. However, most of these materials based on relatively simple binary or ternary oxide systems since the synthesis multicomponent via still is challenge. This work reports for first time production characterization six-oxide basic system...
This work deals with the synthesis and characterization of novel Fe-containing sol-gel materials obtained by modifying composition a binary SiO2-CaO parent glass addition Fe2O3. The effect different processing conditions (calcination in air vs. argon flowing) on formation magnetic crystalline phases was investigated. produced were analyzed from thermal (hot-stage microscopy, differential analysis, calorimetry) microstructural (X-ray diffraction) viewpoints to assess both behavior upon...
Additive manufacturing of bioactive glasses has recently attracted high interest in the field regenerative medicine as a versatile class fabrication methods to process bone substitute materials. In this study, melt-derived glass particles from SiO2-P2O5-CaO-MgO-Na2O-K2O system were used fabricate scaffolds with graded porosity by robocasting. A printable ink made powder and Pluronic F-127 (binder) was extruded into grid-like three-dimensional structure bimodal porosity, i.e., inner part...
In bone tissue engineering research, bioreactors designed for replicating the main features of complex native environment represent powerful investigation tools. Moreover, when equipped with automation, their use allows reducing user intervention and dependence, increasing reproducibility overall quality culture process. this study, an automated uni-/bi-directional perfusion bioreactor combinable pulsed electromagnetic field (PEMF) stimulation culturing 3D models is proposed. A user-friendly...
In recent years, bioactive glasses gained increasing scientific interest in bone tissue engineering due to their capability chemically bond with the host and induce osteogenesis. As a result, several efforts have been addressed use production of three-dimensional (3D) porous scaffolds for regeneration. this work, we creatively combine typical concepts glass processing those waste management propose, first time, bread as new sacrificial template fabrication scaffolds. Preliminary SEM...
Porosity is recognized to play a key role in dictating the functional properties of bioactive scaffolds, especially mechanical performance material. The suitability brittle ceramic and glass scaffolds for bone tissue engineering applications usually evaluated on basis compressive strength alone, which relatively easy assess. This work aims investigate porosity dependence elastic silicate based 45S5 composition. Highly porous glass-ceramic foams were fabricated by sponge replica method their...
Bioactive silicate glass scaffolds were fabricated by a robocasting process in which all the movements of printing head programmed compiling script (text file). A printable ink made powder and Pluronic F-127, acting as binder, was extruded to obtain macroporous with grid-like three-dimensional structure. The scaffold architecture investigated scanning electron microscopy microtomographic analysis, allowed quantifying microstructural parameters (pore size 150-180 μm strut diameter 300 μm). In...
The use of three-dimensional (3D) scaffolds is recognized worldwide as a valuable biomedical approach for promoting tissue regeneration in critical-size bone defects. Over the last 50 years, bioactive glasses have been intensively investigated wide range different clinical applications, from orthopedics to soft healing. Bioactive exhibit unique capability chemically bond host and, furthermore, their processing versatility makes them very appealing due availability manufacturing techniques...
Additive manufacturing has brought about a real revolution in the manufacture of objects variety application areas, overturning traditional paradigm based on subtractive approaches. The potential benefits deriving from these techniques field ceramic materials extend to different industrial sectors, leading shorter, more accurate and cost-effective processes. Within present review, we provide transversal analysis state-of-the-art applications vat-photopolymerization technologies, namely,...
Bioactive glasses are often designed as porous implantable templates in which newly-formed bone can grow three dimensions (3D). This research work aims to investigate the regenerative capability of silicate bioactive glass scaffolds produced by robocasting comparison with powder and granule-like materials (oxide system: 47.5SiO2-10Na2O-10K2O-10MgO-20CaO-2.5P2O5, mol.%). Morphological compositional analyses performed scanning electron microscopy (SEM), combined energy dispersive spectroscopy...