A5073331917- Spaceflight effects on biology
- 3D Printing in Biomedical Research
- Tissue Engineering and Regenerative Medicine
- Force Microscopy Techniques and Applications
- Electromagnetic Fields and Biological Effects
- Bone Tissue Engineering Materials
- Neuroscience and Neural Engineering
- Electrospun Nanofibers in Biomedical Applications
- Metal and Thin Film Mechanics
- Diamond and Carbon-based Materials Research
- Space Exploration and Technology
- Orthopaedic implants and arthroplasty
- Magnetic and Electromagnetic Effects
- Orthopedic Surgery and Rehabilitation
- Additive Manufacturing and 3D Printing Technologies
- Biomedical and Engineering Education
- Medical and Biological Ozone Research
- Geophysics and Sensor Technology
- Planarian Biology and Electrostimulation
- Structural Health Monitoring Techniques
- Optical Imaging and Spectroscopy Techniques
- Muscle activation and electromyography studies
- Shoulder Injury and Treatment
Polytechnic University of Turin
2020-2024
In bone tissue engineering research, bioreactors designed for replicating the main features of complex native environment represent powerful investigation tools. Moreover, when equipped with automation, their use allows reducing user intervention and dependence, increasing reproducibility overall quality culture process. this study, an automated uni-/bi-directional perfusion bioreactor combinable pulsed electromagnetic field (PEMF) stimulation culturing 3D models is proposed. A user-friendly...
The application of biomimetic physical stimuli replicating the in vivo dynamic microenvironment is crucial for vitro development functional cardiac tissues. In particular, pulsed electrical stimulation (ES) has been shown to improve properties cultured cardiomyocytes. However, commercially available stimulators are expensive and cumbersome devices while customized solutions often allow limited parameter tunability, constraining investigation different ES protocols. goal this study was...
Abstract Intrinsic permeability describes the ability of a porous medium to be penetrated by fluid. Considering scaffolds for tissue engineering (TE) applications, this macroscopic variable can strongly influence transport oxygen and nutrients, cell seeding process, transmission fluid forces cells, playing crucial role in determining scaffold efficacy. Thus, accurately measuring could represent an essential step their optimization process. In literature, several methods have been proposed...
In this article, a system to measure the evolution of load in time and space during indoor climbing is described. The based on set dedicated multiaxial cells, which each hold an wall. When climber hangs hold, signal read sent digital acquisition processing system. Sensor design allows for measurement force components applied holds, regardless application point hold. Local deformations were measured through strain gauges. Based electrical configuration gauges, values forces can be computed,...
Human mesenchymal stem cells (hMSCs) sense and respond to biomechanical biophysical stimuli, yet the involved signaling pathways are not fully identified. The clinical application of stimulation including pulsed electromagnetic field (PEMF) has gained momentum in musculoskeletal disorders bone tissue engineering.
Micromechanical characterization by nanoindentation of PDMS substrates for cardiac mechanobiology studies.
In the perspective of reliable methods alternative to in vivo animal testing for cardiac tissue engineering (CTE) research, versatile electrical stimulator ELETTRA has been developed. delivers controlled and stable cardiac-like impulses, it can be coupled already existing bioreactors providing vitro combined biomimetic culture conditions. Designed cost-effective easy use, this device could contribute reduction replacement experiments CTE.
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IntroductionHuman mesenchymal stem cells (hMSCs) sense and respond to biomechanical biophysical stimuli, yet the involved signaling pathways are not fully identified. The clinical application of stimulation including pulsed electromagnetic field (PEMF) has gained momentum in musculoskeletal disorders bone tissue engineering. MethodologyWe herein aim explore role PEMF regeneration by developing trabecular bone-like tissues, then, culturing them under mechanical an automated perfusion...
The ICE Cubes Facility is a capable experiment platform on board the Columbus Module of International Space Station that offers flexibility to host many different experiments. suited for any scientific research and technological demonstrator requires study effects microgravity radiation exposure in pressurised volume. Cube Service also open schooling levels (primary, secondary, universities) STEAM curricula University students (Master PhD) opportunity design, develop, test operate real ISS...
The Artery in Microgravity (AIM) project was the first experiment to be selected for “Orbit Your Thesis!” programme of European Space Agency Academy. It is a 2U cube that will operated International Commercial Experiment (ICE) Cubes facility onboard Station. expected launched on SpaceX-25 mid-2022. being developed by an international group students from ISAE-SUPAERO and Politecnico di Torino. objective study haemodynamics space environment applied coronary heart disease. outcomes this...
Micromechanical characterization by nanoindentation of PDMS substrates for cardiac mechanobiology studies.