A5101834265- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Intraocular Surgery and Lenses
- Preterm Birth and Chorioamnionitis
- Lung Cancer Research Studies
- Neonatal Respiratory Health Research
- Lung Cancer Treatments and Mutations
- Head and Neck Cancer Studies
- Ocular Diseases and Behçet’s Syndrome
- Plant Genetic and Mutation Studies
- Cancer Treatment and Pharmacology
- Traumatic Ocular and Foreign Body Injuries
- Colorectal and Anal Carcinomas
- Metabolism and Genetic Disorders
- Gestational Diabetes Research and Management
- MRI in cancer diagnosis
- Ocular Infections and Treatments
- Infant Development and Preterm Care
- Bariatric Surgery and Outcomes
- Fluid Dynamics and Thin Films
- Anomaly Detection Techniques and Applications
- Coccidia and coccidiosis research
- Arsenic contamination and mitigation
- Ocular Disorders and Treatments
- Organ Transplantation Techniques and Outcomes
Homi Bhabha National Institute
2024
Nethradhama Superspeciality Eye Hospital
2023-2024
Cancer Institute (WIA)
2023-2024
Narayana Health
2023-2024
University of Petroleum and Energy Studies
2023
Jawaharlal Nehru University
2023
Translational Health Science and Technology Institute
2022
Center for Disease Dynamics, Economics and Policy
2021-2022
University of Kalyani
2022
Pacific Dental College and Hospital
2021
<h3>Importance</h3> Worldwide, preterm birth (PTB) is the single largest cause of deaths in perinatal and neonatal period associated with increased morbidity young children. The PTB multifactorial, development generalizable biological models may enable early detection guide therapeutic studies. <h3>Objective</h3> To investigate ability transcriptomics proteomics profiling plasma metabolomics analysis urine to identify measurements PTB. <h3>Design, Setting, Participants</h3> This...
Preterm birth (PTB) is the leading cause of death in children under five, yet comprehensive studies are hindered by its multiple complex etiologies. Epidemiological associations between PTB and maternal characteristics have been previously described. This work used multiomic profiling multivariate modeling to investigate biological signatures these characteristics. Maternal covariates were collected during pregnancy from 13,841 pregnant women across five sites. Plasma samples 231...
The Mycobacterium tuberculosis genome harbors nine toxin-antitoxin (TA) systems that are members of the
<ns3:p>Background First line (1L) TP-Ex-like regimen followed by 2nd-line (2L) immunotherapy represents one of the standards care in platinum-sensitive recurrent and/or metastatic squamous cell carcinoma head and neck (R/M SCCHN). We report our experience from 2 tertiary institutions India. Methods This is a retrospective analysis consecutive patients R/M SCCHN treated with 1L weekly paclitaxel, carboplatin, cetuximab (PCC) maintenance (if non-progressive) or 2L nivolumab oral metronomic...
ABSTRACT Background: The European Organization for the Research and Treatment of Cancer (EORTC) has developed a commonly used validated questionnaire specific to anal cancer (EORTC QLQ-ANL27). It is as an adjunct core EORTC quality-of-life (QoL) QLQ-C30. This was not available in any Indian language, therefore, patients familiar with English could fill it. Objective: We aimed translate validate QLQ-ANL27 module Hindi, Marathi, Bangla languages. Materials Methods: study conducted Department...
Women experience high rates of depression, particularly during pregnancy and the postpartum periods. Using population-based data from Bangladesh Pakistan, we estimated burden antenatal its risk factors, effect on preterm birth.
Babies born early and/or small for gestational age in Low and Middle-income countries (LMICs) contribute substantially to global neonatal infant mortality. Tracking this metric is critical at a population level informed policy, advocacy, resources allocation program evaluation an individual targeted care. Early prenatal ultrasound examination not available these settings, (GA) estimated using new-born assessment, last menstrual period (LMP) recalls birth weight, which are unreliable....
Assessment of gestational age (GA) is key to provide optimal care during pregnancy. However, its accurate determination remains challenging in low- and middle-income countries, where access obstetric ultrasound limited. Hence, there an urgent need develop clinical approaches that allow inexpensive estimations GA. We investigated the ability urinary metabolites predict GA at time collection a diverse multi-site cohort healthy pathological pregnancies (n = 99) using broad-spectrum liquid...
The Mycobacterium tuberculosis genome harbours nine toxin-antitoxin (TA) systems of the mazEF family. These consist two proteins, a toxin and an antitoxin, encoded in operon. While has conserved fold, antitoxins are structurally diverse binding region is typically intrinsically disordered before binding. We describe high throughput methodology for accurate mapping interfacial residues apply it to three MazEF complexes. method involves screening one partner protein against panel chemically...
Abstract Background Hyperglycemia during pregnancy leads to adverse maternal and fetal outcomes. Thus, strict monitoring of blood glucose levels is warranted. This study aims determine the association early mid-pregnancy HbA1c with development complications in women from three countries South Asia Sub-Saharan Africa. Methods We performed a secondary analysis AMANHI (Alliance for Maternal Newborn Health Improvement) cohort, which enrolled 10,001 pregnant between May 2014 June 2018 across...
ABSTRACT Aim: To translate and validate the European Organization for Research Treatment Cancer (EORTC) module assessing sexual health-related quality of life in cancer patients (QLQ-SH22), Hindi, Marathi, Bangla languages clinical use. Methods Results: The EORTC QLQ-SH-22 was translated into by adopting standard guidelines given EORTC. Initially, original questionnaire forward two separate translators, followed reconciliation translations a third person. This back reconciled version English...
<ns4:p><ns4:bold>Background:</ns4:bold> First line (1L) TP-Ex-like regimen followed by 2nd-line (2L) immunotherapy represents one of the standards care in platinum-sensitive recurrent and/or metastatic squamous cell carcinoma head and neck (R/M SCCHN). We report our experience from 2 tertiary institutions India. <ns4:bold>Methods:</ns4:bold> This is a retrospective analysis consecutive patients R/M SCCHN treated with 1L weekly paclitaxel, carboplatin, cetuximab (PCC) maintenance (if...
Globally, 15 million infants are born preterm and another 23.2 small for gestational age (SGA). Determining burden of SGA births, is essential effective planning, modification health policies targeting interventions reducing these outcomes which accurate estimation (GA) crucial. Early pregnancy ultrasound measurements, last menstrual period post-natal neonatal examinations have proven to be not feasible or inaccurate. Proposed algorithms GA in western populations, based on routine new-born...
Introduction: To achieve MDG4 (Millennium Developmental Goals-4), a substantial reduction inearly neonatal deaths will be required. The first steps in improving early survival are todocument the number and rate of identify their common causes. As per NationalFamily Health Survey-3 report, current mortality (NMR) India is 39 1000 livebirths, account for nearly 77% all infant (57/1000) half ofunder-five child (74/1000). This study was undertaken to disease pattern andoutcome neonates admitted...
Background: In the treatment of critically ill children needing specialized airway, respiratory, and hemodynamic assistance, intensive care has become very necessary is typically admitted into pediatric unit (PICU) in order to ensure a better result than if patients were other sections hospital. To audit admissions their findings are significant, which may help change procedures after extensive introspection appropriate, leading improved patient outcomes. Objective examine pattern admission...
The aim of this study was to translate and validate the European Organization for Research Treatment Cancer (EORTC) “Radiation Proctitis” (PRT-20) module in Hindi, Marathi, Bangla languages. EORTC PRT-20 translated into using guidelines. Two separate translators first original questionnaire three regional languages, following which a reconciled forward translation compiled. This version each language then back-translated English by two other translators. compared with correctness,...
Knowledge of gestational age is critical for guiding preterm neonatal care. In the last decade, metabolic dating approaches emerged in response to a global health need; because most developing world, accurate antenatal estimates are not feasible. These methods initially developed North America have now been externally validated two studies countries, however, require shipment samples at sub-zero temperature.A subset 330 pairs heel prick dried blood spot were shipped on dry ice and ambient...