Fahad Aftab
A5024779091- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Global Maternal and Child Health
- Preterm Birth and Chorioamnionitis
- Pregnancy and Medication Impact
- Trace Elements in Health
- Maternal and fetal healthcare
- Child Nutrition and Water Access
- Gestational Diabetes Research and Management
- Maternal and Neonatal Healthcare
- Adolescent Sexual and Reproductive Health
- Neonatal Respiratory Health Research
- Reproductive tract infections research
- Ethics in Clinical Research
- Syphilis Diagnosis and Treatment
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Metabolism and Genetic Disorders
- Advanced MRI Techniques and Applications
- Selenium in Biological Systems
- Maternal and Perinatal Health Interventions
Public Health Laboratory Ivo de Carneri
2021-2023
Jersey Shore University Medical Center
2018
<h3>Importance</h3> Worldwide, preterm birth (PTB) is the single largest cause of deaths in perinatal and neonatal period associated with increased morbidity young children. The PTB multifactorial, development generalizable biological models may enable early detection guide therapeutic studies. <h3>Objective</h3> To investigate ability transcriptomics proteomics profiling plasma metabolomics analysis urine to identify measurements PTB. <h3>Design, Setting, Participants</h3> This...
Background Maternal morbidity occurs several times more frequently than mortality, yet data on burden and its effect maternal, foetal, newborn outcomes are limited in low- middle-income countries. We aimed to generate prospective, reliable population-based the of major direct maternal morbidities antenatal, intrapartum, postnatal periods association with neonatal death South Asia sub-Saharan Africa. Methods findings This is a prospective cohort study, conducted 9 research sites 8 countries...
Preterm birth is the leading cause of child mortality. This study aimed to develop and validate programmatically feasible accurate approaches estimate newborn gestational age (GA) in low resource settings.The WHO Alliance for Maternal Newborn Health Improvement (AMANHI) recruited pregnant women from population-based cohorts five countries (Bangladesh, Ghana, Pakistan, Tanzania Zambia). Women <20 weeks gestation by ultrasound-based dating were enrolled. Research staff assessed newborns for:...
Assessment of gestational age (GA) is key to provide optimal care during pregnancy. However, its accurate determination remains challenging in low- and middle-income countries, where access obstetric ultrasound limited. Hence, there an urgent need develop clinical approaches that allow inexpensive estimations GA. We investigated the ability urinary metabolites predict GA at time collection a diverse multi-site cohort healthy pathological pregnancies (n = 99) using broad-spectrum liquid...
This study aimed to determine the persistence of Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Trichomonas vaginalis (TV) and Mycoplasma genitalium (MG) infections during pregnancy after delivery in vaginal swabs women from Pemba Island, Tanzania. In context an earlier biobanking effort, were collected at two timepoints once post-delivery. Detection CT, NG, TV, MG was performed by PCR using validated detection kits samples 441 pregnant aged 16–48 years old. Among those, 202 matched...
Background: Selenium (Se), an essential trace mineral, has been implicated in preterm birth (PTB). We aimed to determine the association of maternal Se concentrations during pregnancy with PTB risk and gestational duration a large number samples collected from diverse populations.Methods: Gestational data plasma or serum 9946 singleton live births were obtained 17 geographically study cohorts. Maternal determined by Inductively coupled mass spectrometry (ICP-MS) analysis. The associations...
Hypertensive disorders of pregnancy (HDP) are a significant cause maternal mortality worldwide. The classification and treatment hypertension in remain debated. We aim to compare the effectiveness revised 2017 ACC/AHA blood pressure threshold predicting adverse outcomes.
ABSTRACT Background Copper (Cu), an essential trace mineral regulating multiple actions of inflammation and oxidative stress, has been implicated in risk for preterm birth (PTB). We aimed to determine the association maternal plasma/serum Cu concentrations during pregnancy with PTB gestational duration a large multi-cohort study including diverse populations. Methods Gestational data plasma or serum samples 10,449 singleton live births were obtained from 18 geographically cohorts. Maternal...