A5032299870- Musculoskeletal pain and rehabilitation
- Trauma and Emergency Care Studies
- Spine and Intervertebral Disc Pathology
- Cardiac Arrest and Resuscitation
- Medical Imaging Techniques and Applications
- Hip and Femur Fractures
- Radiomics and Machine Learning in Medical Imaging
- Emergency and Acute Care Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Medical Imaging and Analysis
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Health Systems, Economic Evaluations, Quality of Life
- Blood transfusion and management
- Radiation Dose and Imaging
- Clinical practice guidelines implementation
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Trauma Management and Diagnosis
- Neurosurgical Procedures and Complications
- Hemoglobin structure and function
- Bone health and osteoporosis research
- Opioid Use Disorder Treatment
- Scoliosis diagnosis and treatment
- Medical Imaging and Pathology Studies
- Anesthesia and Pain Management
- Cardiovascular Syncope and Autonomic Disorders
Seattle University
2012-2025
University of Washington Medical Center
2025
University of Washington
2012-2023
Oregon Health & Science University
2022
University of Chicago
2022
National Assembly
2022
Kaiser Permanente
2021
VA Puget Sound Health Care System
2021
In-Q-Tel
2016
University of Baltimore
2015
<h3>Importance</h3> Traumatic brain injury (TBI) is the leading cause of death and disability due to trauma. Early administration tranexamic acid may benefit patients with TBI. <h3>Objective</h3> To determine whether treatment initiated in out-of-hospital setting within 2 hours improves neurologic outcome moderate or severe <h3>Design, Setting, Participants</h3> Multicenter, double-blinded, randomized clinical trial at 20 trauma centers 39 emergency medical services agencies US Canada from...
BACKGROUND Optimal resuscitation of hypotensive trauma patients has not been defined. This trial was performed to assess the feasibility and safety controlled (CR) versus standard (SR) in patients. METHODS Patients were enrolled randomized out-of-hospital setting. Nineteen emergency medical services (EMS) systems Resuscitation Outcome Consortium participated. Eligible had an systolic blood pressure (SBP) 90 mm Hg or lower. CR received 250 mL fluid if they no radial pulse SBP lower than 70...
Traumatic arrests have historically had poor survival rates. Identifying salvageable patients and ideal management is challenging. We aimed to (1) describe the outcomes of prehospital traumatic arrests; (2) determine regional variation in survival; (3) identify Advanced Life Support (ALS) procedures associated with survival.This was a secondary analysis cases from Resuscitation Outcomes Consortium Epistry-Trauma Prospective Observational Prehospital Hospital Registry for Trauma (PROPHET)...
Reliance on prehospital trauma triage guidelines misses patients with serious injury. Lactate is a biomarker capable of identifying high-risk patients. Our objective was to compare point-of-care lactate (P-LAC) systolic blood pressure (SBP) for predicting the need resuscitative care (RC) in transported by ground emergency medical services.This prospective observational study at nine sites within Resuscitation Outcomes Consortium conducted from March 2011 August 2012. measured SBP 100 mm Hg...
The Radpeer system is central to the quality assurance process in many radiology practices. Previous studies have shown poor agreement between physicians evaluation of their peers. purpose this study was assess reliability scoring system.A sample 25 discrepant cases extracted from our database. Images were made anonymous; associated reports and identities interpreting radiologists removed. Indications for descriptions discrepancies provided. Twenty-one subspecialist attending rated using...
<h3>Importance</h3> Lumbar spine imaging frequently reveals findings that may seem alarming but are likely unrelated to pain. Prior work has suggested inserting data on the prevalence of among asymptomatic individuals into reports reduce unnecessary subsequent interventions. <h3>Objective</h3> To evaluate impact including benchmark in routine spinal spine-related health care utilization and opioid prescriptions. <h3>Design, Setting, Participants</h3> This stepped-wedge, pragmatic randomized...
Low back pain (LBP) is a common condition made up of variety anatomic and clinical subtypes. Lumbar disc herniation (LDH) lumbar spinal stenosis (LSS) are two subtypes highly associated with LBP. Patients LDH/LSS often started non-surgical treatments if those not effective then go on to have decompression surgery. However, recommendation surgery complicated as the outcome may depend patient's health characteristics. We developed deep learning (DL) model predict for patients LDH/LSS.We used...
In the prehospital tranexamic acid (TXA) for traumatic brain injury (TBI) trial, TXA administered within 2 hours of in out-of-hospital setting did not reduce mortality all patients with moderate/severe (TBI). We examined association between dosing arms, neurologic outcome, and intracranial hemorrhage (ICH) on computed tomography (CT).
Abstract Background: There is disagreement regarding use of hip orthoses after arthroscopic surgery for femoroacetabular impingement syndrome (FAIS). We sought to test whether bracing affects patient outcomes. hypothesized that at 3 and 6 weeks FAIS, patients wearing a brace would have lower mean Numerical Pain Ranking Scales (NPRS) compared who did not wear brace. Secondary goals included comparison additional reported outcome measures, physical exam findings, complications, narcotics,...
Tranexamic acid (TXA) is an antifibrinolytic that has shown some promise in improving outcomes traumatic brain injury (TBI), but only when given early after injury. We examined the association between timing of prehospital TXA administration and patients with moderate to severe TBI.
Among trauma patients with out-of-hospital hypotension, we evaluated the predictive value of systolic blood pressure (SBP) and without other physiologic compromise for identifying requiring early critical resources.This was a secondary analysis prospective cohort injured 13 years or older hypotension (SBP ≤ 90 mm Hg) who were transported by 114 emergency medical service agencies to 56 Level I II centers in 11 regions United States Canada from January 1, 2010, through June 30, 2011. The...
To evaluate the effect of inserting epidemiological information into lumbar spine imaging reports on subsequent nonsurgical and surgical procedures involving thoracolumbosacral sacroiliac joints.Analysis secondary outcomes from Lumbar Imaging with Reporting Epidemiology (LIRE) pragmatic stepped-wedge randomized trial.Primary care clinics within four integrated health systems in United States.238,886 patients ≥18 years age who received diagnostic between 2013 2016.Clinics were to receive text...
Pre-hospital resuscitation of critically injured patients traditionally includes supplemental oxygen therapy to address potential hypoxemia. The objective this study was explore the association between pre-hospital hypoxemia, hyperoxemia, and mortality in with traumatic brain injury (TBI) shock. We hypothesized that both hypoxemia hyperoxemia would be associated increased mortality. used Resuscitation Outcomes Consortium Prospective Observational Prehospital Hospital Registry for Trauma (ROC...
Abstract Background Chronic low back pain (cLBP) is widespread, costly, and burdensome to patients health systems. Little known about non-pharmacological treatments for the secondary prevention of cLBP. There some evidence that addressing psychosocial factors in higher risk are more effective than usual care. However, most clinical trials on acute subacute LBP have evaluated interventions irrespective prognosis. Methods We designed a phase 3 randomized trial with 2 × factorial design. The...
A 2-g bolus of tranexamic acid (TXA) has been shown to reduce 28-day mortality in a randomized controlled trial. This study investigates whether out-of-hospital TXA use is associated with adverse events or unfavorable outcomes suspected traumatic brain injury (TBI) when intracranial hemorrhage (ICH) absent on initial computed tomography.This used data from 2015 2017, multicenter, trial studying the effect following doses moderate severe TBI: bolus, 1-g plus infusion over 8 hours, and placebo...
Background: Prehospital vital signs are the basis of many triage and transport guidelines. They serve to activate prehospital in-hospital trauma systems, direct resuscitation efforts other interventions. Objective: The purpose this study was determine relationship systolic blood pressure with emergent procedures mortality. Methods: Included in secondary analysis Resuscitation Outcomes Consortium (ROC) Hypertonic Saline Clinical Trial patients 15 years or older who were enrolled shock cohort....
<h3>Background:</h3> To describe characteristics of patients, providers, and clinics associated with opioid or non-opioid pain medication prescribing patterns for patients who received lower spine imaging in primary care clinics. <h3>Methods:</h3> In these secondary analyses the Lumbar Imaging Reporting Epidemiology (LIRE) study, a randomized controlled trial conducted 4 health systems United States, we evaluated receipt prescriptions. The outcomes were prescriptions or, separately,...