A5003041897- Environmental Toxicology and Ecotoxicology
- Pharmaceutical and Antibiotic Environmental Impacts
- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Polyamine Metabolism and Applications
- Meat and Animal Product Quality
- Toxic Organic Pollutants Impact
- Mercury impact and mitigation studies
- Reproductive biology and impacts on aquatic species
- Effects and risks of endocrine disrupting chemicals
- Pesticide and Herbicide Environmental Studies
- Antibiotics Pharmacokinetics and Efficacy
- Pharmacological Effects and Assays
- Analytical chemistry methods development
- Synthesis and Characterization of Heterocyclic Compounds
- Animal Behavior and Welfare Studies
- Advanced Chemical Sensor Technologies
- Veterinary Medicine and Surgery
- Fish Ecology and Management Studies
- Mycotoxins in Agriculture and Food
- Animal Nutrition and Physiology
- Marine animal studies overview
- Per- and polyfluoroalkyl substances research
- Agriculture, Plant Science, Crop Management
- Veterinary Pharmacology and Anesthesia
University of Veterinary Sciences Brno
2015-2025
Animal Welfare Institute
2024
Faculty of Public Health
2013
Veterinary Research Institute
2007
Masaryk University
2002
Pesticides and personal care products are two very important groups of contaminants posing a threat to the aquatic environment organisms living in it.. Therefore, this study aimed describe effects widely used pesticides parabens on non-target biota such as fish (using model
Assessment of diclofenac LC50 reference values in juvenile and embryonic stages the zebrafish ( Danio rerio ) The aim study was to compare acute toxicity ). Acute tests were performed on aquarium fish , which is one model organisms most commonly used testing. using a semi-static method according OECD guideline No. 203 (Fish, test). Embryo embryos compliance with 212 methodology short-term test embryo sac-fry stages). results subjected probit analysis EKO-TOX 5.2 programme determine 96hLC50...
In the present study, effects of sub-lethal sub-chronic doses ibuprofen, diclofenac, and carbamazepine alone, in combination (concentration range 0.02-60 µg/l), on early life stages tench (Tinca tinca) were investigated. The lower concentrations pharmaceuticals tested (0.02, 0.2, 2 µg/l) represent concentration values these substances commonly surface waters or effluents from wastewater treatment plants. Multiple biomarkers biotransformation, antioxidant defence systems, lipid peroxidation...
The aim of study was to evaluate the effect atrazine exposure (5, 15, 20, and 30 mg·L −1 ) on common carp ability regeneration. During 96 h we observed abnormal behavior in fish exposed 20 . Mortality histological alterations were noticed only group Most experimental groups showed significantly (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>P</mml:mi><mml:mo><</mml:mo><mml:mn mathvariant="normal">0.05</mml:mn></mml:math>) lower values haemoglobin, haematocrit,...
The aim of the study was to investigate effects subchronic exposure zebrafish ( Danio rerio ) a fluoroquinolone norfloxacin, using selected oxidative stress parameters as target. Toxicity tests were performed on according OECD Guidelines number 203 and 215. In Subchronic Test, significant (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>P</mml:mi><mml:mo><</mml:mo><mml:mn>0.01</mml:mn></mml:math>) increase in activity glutathione peroxidase, S-transferase,...
The aim of this study was to investigate effects subchronic exposure sublethal levels diclofenac on growth, oxidative stress, and histopathological changes in Danio rerio . juvenile growth tests were performed according OECD method number 215. Fish at the age 20 days exposed environmental concentration commonly detected Czech rivers (0.02 mg L −1 ) range concentrations (5, 15, 30, 60 for 28 days. A significant decrease (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
The present study aimed to evaluate the biochemical and antioxidant responses of common carp after exposure antiepileptic analgesic drug gabapentin at concentrations 0.1, 1, 10, 100 μg/l for 4 weeks. highest two resulted in significant changes plasma indices such as glucose (only group μg/l), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), lipase, creatine kinase (CK), amylase well butyrylcholinesterase (BChE). Similar trends were found both groups exposed environmentally...
Abstract Pollution of the aquatic ecosystem by hormone‐active substances is a frequently discussed topic these days. Such can pass through sewage treatment plant system and affect life. This study tested effect 17α‐ethinylestradiol (EE2) on individual zebrafish ( Danio rerio ) at an environmentally relevant concentration in fish food (10 μg/kg) 100 times higher (1000 μg/kg). experiment revealed significant changes expression reproductive genes, increase vitellogenin levels histopathological...
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Ubiquitous occurrence of pharmaceuticals in aquatic environment results concern about potential adverse the effects on nontarget organisms. In water, drugs are present complex mixtures, which complicated interactions affect toxicity single components. The purpose this study was to examine effect 35-day-long exposure mixture ibuprofen, diclofenac, and carbamazepine mortality, growth, early ontogeny, histopathological changes tench (Tinca tinca). Early life stage test carried out using a...
Polycyclic musk compounds are commonly used in personal care products to replace expensive natural fragrances. Due their huge consumption, they have become a part of the aquatic environment. In present study, two-month exposure effect tonalide on juvenile zebrafish (Danio rerio) was investigated. We determined vitellogenin concentration define potential endocrine-disrupting and also analysed selected indices evaluate induction oxidative stress. The environmentally relevant (i.e., 500 ng/l)...